supported by grants from the National Key R&D Program of China (No.2022YFC2703701 to Qiji Liu);the National Natural Science Foundation of China (No.82271901,32070586);the Shandong Provincial Natural Science Foundation,China (No.ZR2020MH086);Taishan Scholar Program of Shandong Province (tsqn202211318);NHC Key Laboratory of Birth Defects Prevention,China (No.ZD202101).
Triple-negative breast cancer(TNBC)is defined by the lack of estrogen receptor(ER),progesterone receptor,and amplified human epidermal growth factor receptor expression.TNBC accounts for~15%of all breast cancer cases ...
supported by grants from the National Key Research and Development Program of China(No.2023YFC3503400);the National Nature Science Foundation of China(No.82074097);the Key Program of National Nature Science Foundation of China(No.82030113);Shanghai Science and Technology Funds(No.17ZR1401700);Shanghai Municipal Health Commission Project(No.201740200);Shanghai Engineering Research Center of Immunotherapeutics(No.19DZ2251400).
Baicalin(BA),a natural component found in many traditional Chinese medicines,exerts protective effects against several viruses.Although our previous studies have revealed that the anti-hepatitis B virus(anti-HBV)activ...
supported by the National Natural Science Foundation of China (No. 8196140154);the Natural Science Foundation of Xinjiang Uygur Autonomous Region (Nos.2023D01C139 and 2023D01C63);the State Key Laboratory of Pathogenesis,Prevention and Treatment of High Incidence Diseases in Central Asia Fund (No. SKL-HIDCA-2020-8)。
Tianxiangdan(TXD),a traditional Chinese herbal remedy,demonstrates efficacy in mitigating myocardial ischemia-reperfusion(I/R)-induced damage.This study employed network pharmacology to evaluate the therapeutic target...
目的:探讨补肾健脾活血方对过表达分泌型卷曲相关蛋白1(secreted frizzled related protein 1,SFRP1)、沉默SFRP1的UMR106细胞成骨分化及雌激素受体α(estrogen receptorα,ERα)的影响。方法:通过构建SFRP1过表达及沉默重组腺病毒载体...