EUDRAGIT

作品数:89被引量:237H指数:7
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Eudragit<sup>®</sup>-PEG Nanoparticles: Physicochemical Characterization and Interfacial Tension Measurements
《Open Journal of Biophysics》2024年第2期121-131,共11页Papa Mady Sy Sidy Mouhamed Dieng Alphonse Rodrigue Djiboune Louis Augustin Diaga Diouf Boucar Ndong Gora Mbaye Mounibé Diarra 
The objectives of this study are to understand the mechanisms involved in the stabilization of water/oil interfaces by polymeric nanoparticles (NPs) (Eudragit®). Eudragit L100 NPs of various sizes and Zeta potentials ...
关键词:NANOPARTICLES Eudragit® PEG Interfacial Tension Pickering Emulsion 
广藿香油肠溶滴丸制备及其对溃疡性结肠炎大鼠的药效评价被引量:2
《中国现代应用药学》2024年第12期1621-1630,共10页李晓锋 陈卫东 陈华源 许玮华 刘二刚 申欢 王冰 黄永焯 
中国科学院药物创新研究院自主部署项目(CASIMM0120184002);上海市科委自然基金项目(21ZR1475200);中山市引进科研创新团队项目(CXTD2022011);中山市第一批科技创新领军人才资助项目(LJ2021001)。
目的 制备广藿香油肠溶滴丸,评价其结肠靶向释放性能,并验证其对大鼠溃疡性结肠炎(ulcerative colitis,UC)的治疗作用。方法 单因素结合响应面优化法筛选基质种类及优化制备工艺参数;以体外溶出度为指标,筛选和确定Eudragit包衣处方和...
关键词:广藿香油 肠溶滴丸 结肠靶向释放 溃疡性结肠炎 EUDRAGIT 
Compatibility studies of the Thiocolchicoside with Eudragit RLPO,Eudragit E100 and Eudragit L100 using thermal and non-thermal methods
《Drug Combination Therapy》2022年第1期1-9,共9页Nishant Thakur Bhupinder Kaur Manish Goswami Chandan Sharma 
This work was carried out under the financial support received from Ministry of Science&Technology,Department of Science and Technology New Delhi,Govt of India(File No SP/YO/063).
Aim:Thiocolchicoside is a sulfur derivative of the colchicine widely used as the skeletal muscle relaxant in variety of muscle related disorders.Compatibility of the Thiocolchicoside is screened with the Eudragit RLPO...
关键词:Thiocolchicoside Relative humidity EUDRAGIT Compatibility Fourier transform infrared Differential scanning calorimetry 
Physicochemical and in Vitro Antibacterial Evaluation of Metronidazole Loaded Eudragit S‑100 Nanofbrous Mats for the Intestinal Drug Delivery被引量:2
《Advanced Fiber Materials》2022年第1期76-88,共13页Priyanka Prakash Rade Prabhanjan Shridhar Giram Ajinkya A.Shitole Neeti Sharma Baijayantimala Garnaik 
Ms.Priyanka P.Rade gratefully acknowledges the Department of Science and Technology,New Delhi,India for the award of DST-INSPIRE fellowship(IF160594)for her doctoral research;The authors also gratefully acknowledge LIA MATSUCAT,France for the collaboration;The authors express their heartfelt gratitude to Evonik Industries,Mumbai,India,for providing Eudragit S 100 as a gift sample.
Metronidazole(MTZ)loaded Eudragit S-100(ES-100)nonwoven nanofbrous mats were successfully electrospun and evaluated for intestinal drug delivery.MTZ was varied in the range of 1–15%(w/w)in ES-100 nanofbrous mats,the ...
关键词:ES-100 METRONIDAZOLE Nanofbers Antibacterial Intestinal drug delivery 
吲哚美辛肠溶Eudragit L 100-55聚合物纳米粒的制备
《山东第一医科大学(山东省医学科学院)学报》2021年第7期497-500,共4页李丽 刘珂 马文青 曲哲哲 郝吉福 龙跃洲 
国家级大学生创新创业训练计划(201710439109)。
目的制备吲哚美辛肠溶Eudragit L 100-55聚合物纳米粒。方法以pH依赖型的聚合物Eudragit L 100-55作为肠溶载体材料,聚乙烯醇为稳定剂,以粒径、包封率和载药量为响应值,采用纳米沉淀法制备吲哚美辛肠溶纳米粒,利用中心点效应面设计优化...
关键词:吲哚美辛 肠溶纳米粒 中心点效应面设计 
Electrospun Aspirin/Eudragit/Lipid Hybrid Nanofibers for Colon-targeted Delivery Using an Energy-saving Process被引量:1
《Chemical Research in Chinese Universities》2021年第3期443-449,共7页WANG Yibin TIAN Liang ZHU Tianhao MEI Jing CHEN Zezhong YU Deng-Guang 
This study was supported by the Natural Science Foundation of Shanghai,China(No.20ZR1439000);the USST college student innovation projects,China(Nos.SH2020227&XJ2020376-2020378).
Both electrospinning apparatus and their commercial products are extending their applications in a wide variety of fields.However,very limited reports can be found about how to implement an energy-saving process and i...
关键词:Coaxial spinneret Polymer/lipid hybrid fibers Colon-targeted ASPIRIN COVID-19 
A stepwise optimization strategy to formulate in situ gelling formulations comprising fluconazole-hydroxypropyl-beta-cyclodextrin complex loaded niosomal vesicles and Eudragit nanoparticles for enhanced antifungal activity and prolonged ocular delivery被引量:2
《Asian Journal of Pharmaceutical Sciences》2020年第5期617-636,共20页Heba Elmotasem Ghada E.A.Awad 
the National Research Centre,Cairo,Egypt for all the facilities and supports。
Fungal keratitis and endopthalmitis are serious eye diseases.Fluconazole(FL)is indicated for their treatment,but suffers from poor topical ocular availability.This study was intended to improve and prolong its ocular ...
关键词:FLUCONAZOLE Ocular Eudragit nanoparticles CYCLODEXTRIN NIOSOMES In situ gel 
Artificial Nanoscale Erythrocytes from Clinically Relevant Compounds for Enhancing Cancer Immunotherapy被引量:1
《Nano-Micro Letters》2020年第7期156-174,共19页Wenquan Ou Kang Sik Nam Dae Hoon Park Jungho Hwang Sae Kwang Ku Chul Soon Yong Jong Oh Kim Jeong Hoon Byeon 
supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Science,ICT and future Planning(2018R1A2A1A05020683);supported by the NRF(2018R1A2A2A05021143)grant funded by the Korean Government;the Medical Research Center Program(2015R1A5A2009124)through the NRF funded by MSIP.
Because of enhanced e cacy and lower side e ects,cancer immunotherapies have recently been extensively investigated in clinical trials to overcome the limitations of conventional cancer monotherapies.Although engineer...
关键词:Cancer IMMUNOTHERAPIES Air–liquid two-phase ELECTROSPRAY Paclitaxel-loaded FAKE blood cell EUDRAGIT particle Translatable chemo-immunotherapeutic NANOSYSTEMS Anti-PD-L1 antibodies 
Eudragit^(■) RL30D/ L30D-55水分散体膜性能的研究
《科学咨询》2020年第14期28-29,共2页刘阳 刘艺萍 林凤云 邱妍川 马潋 江尚飞 张天竹 
重庆市卫生健康委员会医学科研项目(No.2015ZBXM063);重庆市医药高等专科学校科研项目(No.ygz2015111)。
目的:研究Eudragit~? RL30D/ L30D-55包衣膜的机械性能和透湿性能,对其包衣应用提供合理依据。方法:采用平面铸膜法制备游离膜,以微机控电子万能试验机拉伸膜测定机械性能参数,以吸湿试验测定膜透湿性能参数。结果:Eudragit~? RL30D膜...
关键词:Eudragit^(■) RL30D/L30D-55 水分散体膜 性能 
用于透皮给药的新型载pH敏感型纳米粒的水凝胶的研制被引量:1
《中国医药工业杂志》2019年第4期463-463,共1页QINDEELM 王盈(编译) 
将药物负载于pH敏感型聚合物载体中,利用皮肤表面和血循环间pH值的差异可以透皮递送药物分子。本试验以吡罗昔康为模型药物、能在pH7.4以上介质中溶解的pH敏感型聚合物Eudragit S00(ES100)为载体,采用纳米沉淀法制备纳米粒。
关键词:pH敏感型 透皮给药 纳米粒 水凝胶 EUDRAGIT 聚合物载体 研制 药物分子 
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