EVASION

作品数：70被引量：200H指数：6
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相关领域：医药卫生更多>>
相关作者：李志晖更多>>
相关机构：四川师范大学南京大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国航空科学基金更多>>
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Hepatitis B virus confers innate immunity evasion through hepatitis B virus-miR-3 down-regulation of cGAS-Sting-IFN signaling
《World Journal of Hepatology》2025年第2期159-169,共11页Zhen-Yu Xu Jia-Shi Gao Ying He Xin-Qiang Xiao Guo-Zhong Gong Min Zhang 
Supported by National Natural Science Foundation of China,Key Project,No.82430071;The Scientific Research Program of FuRong Laboratory,No.2023SK2108;Clinical Medical Research Center for Viral Hepatitis of Hunan Province,No.2023SK4009;Hunan Provincial Natural Science Foundation,No.2023JJ60440;Hunan Provincial Health Commission Research Program,No.C202303088786.
BACKGROUND Hepatitis B virus(HBV)evades the innate immunity and leads to persistent chronic infection,but the molecular mechanism is still not well known.AIM To investigate whether HBV-miR-3 is involved in HBV immune ...
关键词：Hepatitis B virus HBV-miR-3 cGAS Sting IFN-Β 
Deep reinforcement learning based integrated evasion and impact hierarchical intelligent policy of exo-atmospheric vehicles
《Chinese Journal of Aeronautics》2025年第1期409-426,共18页Leliang REN Weilin GUO Yong XIAN Zhenyu LIU Daqiao ZHANG Shaopeng LI 
co-supported by the National Natural Science Foundation of China(No.62103432);the China Postdoctoral Science Foundation(No.284881);the Young Talent fund of University Association for Science and Technology in Shaanxi,China(No.20210108)。
Exo-atmospheric vehicles are constrained by limited maneuverability,which leads to the contradiction between evasive maneuver and precision strike.To address the problem of Integrated Evasion and Impact(IEI)decision u...
关键词：Exo-atmospheric vehicle Integrated evasion and impact Deep reinforcement learning Hierarchical intelligent policy Single-chip microcomputer Miss distance 
Luring cooperative capture guidance strategy for the pursuit—evasion game under incomplete target information
《Astrodynamics》2024年第4期675-688,共14页Wenxue Chen Yudong Hu Changsheng Gao Wuxing Jing 
cosupported by the National Natural Science Foundation of China(Nos.12072090 and 12302056);the Postdoctoral Fellowship Program of CPSF(No.GZC20233445);the Heilongjiang Postdoctoral Financial Assistance(No.LBH-Z23147).
In this work,we attempt to investigate a luring cooperative guidance strategy for three-player inducer–defender–attacker engagement with field-of-view(FOV)and overload constraints against an attacker with speed adva...
关键词：adaptive backstepping luring defense technology overload constraint field-of-view(FOV)constraint missile guidance distributed cooperative 
Single-cell and machine learning approaches uncover intrinsic immune-evasion genes in the prognosis of hepatocellular carcinoma
《Liver Research》2024年第4期282-294,共13页Jiani Wang Xiaopeng Chen Donghao Wu Changchang Jia Qinghai Lian Yuhang Pan Jiumei Yang 
the Natural Science Foundation of Guangdong Province(No.2017A030310252,No.2022A1515012650);the Science and Technology Program of Guangzhou(No.2024A03J0919).
Background and aims:Hepatocellular carcinoma(HCC)is a tumor of high heterogeneity and complexity,which poses significant challenges to effective treatment and patient prognosis because of its immune evasion characteri...
关键词：Hepatocellular carcinoma(HCC) Intrinsic immune-evasion genes(IIEGs) The Cancer Genome Atlas(TCGA) Machine learning Single-cell analysis 
Nasal mucosal secretory immunoglobulin A but not serum antibodies is resistant to Omicron evasion
《hLife》2024年第9期488-491,共4页Si Chen Zhengyuan Zhang Qian Wang Pingchao Li Feng Li Ling Chen 
supported by the National Natural Science Foundation of China to L.C.(92269201);a grant from Guangzhou Laboratory(GZNL2023A01009);Science and Technology Projects in Guangzhou(SL2022A04J00604);State Key Laboratory of Respiratory Disease SKLRD-Z-202106 to S.C.;Youth Innovation Promotion Association of CAS to P.L.(2022361).
Intramuscular vaccines against severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)can effectively alleviate the severity of SARS-CoV-2-caused disease and reduce mortality.However,they cannot effectively preven...
关键词：MUCOSAL protective IMMUNITY 
From Entry to Evasion:A Comprehensive Analysis of Host-Virus Interactions for Monkeypox
《Infectious Microbes & Diseases》2024年第2期56-64,共9页Vahideh Hamidi Sofiani Mohammad Rezaei Zadeh Rukerd Javad Charostad Mohammad Pardeshenas Reza Ghazi Nasir Arefinia Sara Shafieipour Faranak Salajegheh Mohsen Nakhaie 
Monkeypox(Mpox)has posed a novel challenge and emerged as a threat to global public health since the onset of its outbreak in 2022.Mpox is spreading throughout the world in both endemic and non-endemic countries,indic...
关键词：MONKEYPOX IMMUNITY apoptosis virus-host interaction 
Mutations in the SARS-CoV-2 spike receptor binding domain and their delicate balance between ACE2 affinity and antibody evasion
《Protein & Cell》2024年第6期403-418,共16页Song Xue Yuru Han Fan Wu Qiao Wang 
supported by the National Key Research and Development Program(2023YFC0872600 and 2021YFA1301400);the National Natural Science Foundation of China(32070947 and 32370943);the Shanghai Municipal Science and Technology Major Project(ZD2021CY001);supported by the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(2023-PT310-02).
Intensive selection pressure constrains the evolutionary trajectory of SARS-CoV-2 genomes and results in various novel variants with distinct mutation profiles.Point mutations,particularly those within the receptor bi...
关键词：ACE2 AFFINITY maintained 
An Empirical Study on the Effectiveness of Adversarial Examples in Malware Detection
《Computer Modeling in Engineering & Sciences》2024年第6期3535-3563,共29页Younghoon Ban Myeonghyun Kim Haehyun Cho 
supported by Institute of Information&Communications Technology Planning&Evaluation(IITP)Grant funded by the Korea government,Ministry of Science and ICT(MSIT)(No.2017-0-00168,Automatic Deep Malware Analysis Technology for Cyber Threat Intelligence).
Antivirus vendors and the research community employ Machine Learning(ML)or Deep Learning(DL)-based static analysis techniques for efficient identification of new threats,given the continual emergence of novel malware ...
关键词：Malware classification machine learning adversarial examples evasion attack CYBERSECURITY 
A novel evasion guidance for hypersonic morphing vehicle via intelligent maneuver strategy被引量：1
《Chinese Journal of Aeronautics》2024年第5期441-461,共21页Xun LI Xiaogang WANG Hongyu ZHOU Yu LI 
This work was supported by the National Natural Science Foundation of China(No.52202438).
This paper presents a novel evasion guidance law for hypersonic morphing vehicles,focusing on determining the optimized wing's unfolded angle to promote maneuverability based on an intelligent algorithm.First,the purs...
关键词：Hypersonic vehicles Variable-sweep wings Evasion guidance Reinforcement learning Pursuit-evasion problem 
Unsynchronized butyrophilin molecules dictate cancer cell evasion of Vγ9Vδ2 T-cell killing被引量：1
《Cellular & Molecular Immunology》2024年第4期362-373,共12页Zeguang Wu Qiezhong Lamao Meichao Gu Xuanxuan Jin Ying Liu Feng Tian Ying Yu Pengfei Yuan Shuaixin Gao Thomas S.Fulford Adam P.Uldrich Catherine C.L Wong Wensheng Wei 
funding from the National Science Foundation of China(31930016);the Peking-Tsinghua Center for Life Sciences;ZW received funding from the State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases(2024KF00001);the National Science Foundation of China(82350119);CCW received funding from the Talent Introduction Funds from the Chinese Academy of Medical Science(2022-RC310-10);the National Science Foundation of China(32150005);the Research Funds from Health@InnoHK Program,launched by the Innovation Technology Commission of the Hong Kong Special Administrative Region.
Vγ9Vδ2 T cells are specialized effector cells that have gained prominence as immunotherapy agents due to their ability to target and kill cells with altered pyrophosphate metabolites.In our effort to understand how ...
关键词：BUTYROPHILIN Vγ9Vδ2 T-cell Cancer-specific immune evasion Glutaminyl-peptide cyclotransferase-like Pyrophosphate metabolite Immunotherapy 
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