BUTYROPHILIN

作品数：7被引量：5H指数：1
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相关领域：农业科学生物学更多>>
相关期刊：《Journal of Animal Science and Biotechnology》《Cellular & Molecular Immunology》《Signal Transduction and Targeted Therapy》更多>>
相关基金：国家自然科学基金更多>>
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Unsynchronized butyrophilin molecules dictate cancer cell evasion of Vγ9Vδ2 T-cell killing被引量：1
《Cellular & Molecular Immunology》2024年第4期362-373,共12页Zeguang Wu Qiezhong Lamao Meichao Gu Xuanxuan Jin Ying Liu Feng Tian Ying Yu Pengfei Yuan Shuaixin Gao Thomas S.Fulford Adam P.Uldrich Catherine C.L Wong Wensheng Wei 
funding from the National Science Foundation of China(31930016);the Peking-Tsinghua Center for Life Sciences;ZW received funding from the State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases(2024KF00001);the National Science Foundation of China(82350119);CCW received funding from the Talent Introduction Funds from the Chinese Academy of Medical Science(2022-RC310-10);the National Science Foundation of China(32150005);the Research Funds from Health@InnoHK Program,launched by the Innovation Technology Commission of the Hong Kong Special Administrative Region.
Vγ9Vδ2 T cells are specialized effector cells that have gained prominence as immunotherapy agents due to their ability to target and kill cells with altered pyrophosphate metabolites.In our effort to understand how ...
关键词：BUTYROPHILIN Vγ9Vδ2 T-cell Cancer-specific immune evasion Glutaminyl-peptide cyclotransferase-like Pyrophosphate metabolite Immunotherapy 
Novel insights into regulation of butyrophilin molecules:critical components of cancer immunosurveillance by yo T cells
《Cellular & Molecular Immunology》2024年第4期409-411,共3页Dieter Kabelitz 
supported by Deutsche Forschungsgemeinschaft DFG grant Ka502/19-3.Open Access funding enabled and organized by Projekt DEAL.
Members of the butyrophilin(BTN)family of transmembrane molecules play an important role in the activation of humanγδT cells.In recent years,it has been discovered that BTN3A1 and BTN2A1 are indispensable in this pr...
关键词：expression. INSIGHT CRITICAL 
The Vγ4/butyrophilin conspiracy: novel role of intraepithelial γδ T cells in chronic inflammatory bowel disease
《Signal Transduction and Targeted Therapy》2023年第12期5575-5577,共3页Dieter Kabelitz 
Open Access funding enabled and organized by Projekt DEAL.
In a recent article published in Science,Dart and colleagues reported that colonic T cells expressing the Vγ4 T-cell receptor(TCR)interact with epithelial butyrophilin-like(BTNL)proteins BTNL3 and BTNL8 in healthy in...
关键词：BOWEL INFLAMMATORY DISEASES 
Knockout of butyrophilin subfamily 1 member A1(BTN1A1) alters lipid droplet formation and phospholipid composition in bovine mammary epithelial cells被引量：4
《Journal of Animal Science and Biotechnology》2020年第4期975-985,共11页Liqiang Han Menglu Zhang Zhiyang Xing Danielle N.Coleman Yusheng Liang Juan J.Loor Guoyu Yang 
supported by the National Natural Science Foundation of China (U1904116);Special Funds for Modern Agricultural Industry Technology System (CARS-37);National Key Research and Development Program of China (Beijing, China;2016YFD0500503)。
Background: Milk lipids originate from cytoplasmic lipid droplets(LD) that are synthesized and secreted from mammary epithelial cells by a unique membrane-envelopment process. Butyrophilin 1 A1(BTN1 A1) is one of the ...
关键词：Lipid droplet Mammary epithelial cell Milk fat globule PHOSPHOLIPID 
Critical role of butyrophilin 3A1 in presenting preny pyrophosphate antigens to human y~ T cells
《Cellular & Molecular Immunology》2014年第2期117-119,共3页Dieter Kabelitz 
Tlymphocytes recognize antigen via the heterodimeric T-cell receptor（TCR） which is closely associated with the signal-transducing CD3 complex. αβ TCR-expressing T cells recognize peptides presented by MHC class II...
关键词：T细胞受体 抗原 焦磷酸 脂蛋白 人类 细胞识别 异源二聚体 T淋巴细胞 
Butyrophilin 3A 1 presents phosphoantigens to human yδ T cells： the fourth model of antigen presentation in the immune system
《Cellular & Molecular Immunology》2014年第2期123-125,共3页
Tlymphocytes are major players in immunity, providing protectionagainst pathogenic microorganisms and tumors. They achieve this goal because they express clonally distributed recep- tors （T-cell receptor, TCR） on th...
A fat story--antigen presentation by butyrophilin 3A1 to γδ T cells
《Cellular & Molecular Immunology》2014年第1期5-7,共3页Charlotte Esser 
Antigen specificity and receptor diversity are hallmarks of B and T cells. Only 1%-5% of all T cells bear a γδ T-cell receptor （TCR）, and these cells have features of both innate and adaptive cells. While the anti...
关键词：T细胞 抗原提呈 脂蛋白 故事 AE 细胞受体 抗原特异性 抗原递呈 
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