EXTRACELLULAR_MATRIX

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Microglia as hackers of the matrix:sculpting synapses and the extracellular space
《Cellular & Molecular Immunology》2021年第11期2472-2488,共17页Joshua D.Crapser Miguel A.Arreola Kate I.Tsourmas Kim N.Green 
This work was supported by the National Institutes of Health(NIH)under awards R01NS083801(NINDS),RF1AG056768(NIA),RF1AG065329(NIA),and U54 AG054349(NIA Model Organism Development and Evaluation for Late-onset Alzheimer’s Disease(MODEL-AD))to K.N.G.,F31NS108611(NINDS)to J.D.C.,and F31NS111882(NINDS)to M.A.A.We thank Rocio A.Barahona for providing whole-brain slidescan and 20×confocal images of microglia-depleted mouse brain sections immunohistochemically stained for perineuronal nets.The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Microglia shape the synaptic environment in health and disease,but synapses do not exist in a vacuum.Instead,pre-and postsynaptic terminals are surrounded by extracellular matrix(ECM),which together with glia comprise...
关键词：NEUROSCIENCE Perineuronal nets MICROGLIA Extracellular matrix NEUROINFLAMMATION 
Analysis of structural components of decellularized scaffolds in renal fibrosis被引量：9
《Bioactive Materials》2021年第7期2187-2197,共11页Rui Zhang Junqun Jiang Yaling Yu Fangfang Wang Niuniu Gao Yingjie Zhou Xinlong Wan Zhibin Wang Peng Wei Jin Mei 
The authors would like to acknowledge the Institute of Bioscaffold Transplantation and Immunology whose research was funded by the National Natural Science Foundation of China(grant NO.81970653);And the Medical Research Center of Ningbo City First Hospital whose research was funded by Zhejiang Medical and Health Technology Project(grant No.2018248656);Zhejiang pharmacy Top Key Project(grant No.YKFJ2-008).
Chronic kidney disease has been recognized as a major public health problem worldwide and renal fibrosis is a common pathological process occurring in chronic renal failure.It is very promising to find the strategies ...
关键词：Extracellular matrix PROTEOMICS Growth factor Tissue engineering Chronic renal diseases 
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