Supported by Hebei Province 2023 Annual Medical Science Research Project,No.20230597;Hebei Province 2024 Annual Medical Applicable Technology Tracking Project,No.GZ2024017.
BACKGROUND Fungal esophagitis(FE)is caused by fungal invasion of the esophageal mucosa.Under endoscopy,the esophageal mucosa shows edema,congestion,erosion,and ulceration,and bleeds easily when touched,and the surface...
Objective To investigate the efficacy and safety of liposomal amphotericin B(L-AmB)for the salvage treatment of invasive fungal disease(IFD)in patients withhematologicaldiseases.MethodsDatawere retrospectively collect...
Background: Chronic ulcers are responsible for considerable morbidity and significantly contribute to the escalation in the cost of health care. Chronic leg ulcers (CLUs) are susceptible to microbial infections and se...
Supported by National Natural Science Foundation of China,No.U23A20398 and No.82030007;Sichuan Science and Technology Program,No.2022YFS0578.
This article reviews of the original research published by Wu et al in the World Journal of Gastroenterology,delving into the pivotal role of the gut microbiota in the pathogenesis of Crohn's disease(CD).Insights were...
financially supported by the National Key R&D Program of China(2021YFC2302100);the National Natural Science Foundation of China(82370005 and 82172291);the National Key R&D Program of China(2022YFC2303000 and 2021YFC230000);the CAS Interdisciplinary Innovation Team,the Beijing Research Center for Respiratory Infectious Diseases Project(BJRID2024-008 and BJRID2024-011);the R&D Program of Beijing Municipal Education Commission(KM202410025012);the Reform and Development Program of Beijing Institute of Respiratory Medicine(Ggyfz202328 and Ggyfz202418);the National Key R&D Program of China(2020YFA0907200);Shanghai Science and Technology Innovation Action Plan 2023“Basic Research Project”(23JC1404201);the Shanghai‘‘Belt and Road’’Joint Laboratory Project(22490750200);the National Natural Science Foundation of China(82370005);National High Level Hospital Clinical Research Funding(2022-PUMCH-C-052).
Strains from the Cryptococcus gattii species complex(CGSC)have caused the Pacific Northwest cryptococcosis outbreak,the largest cluster of lifethreatening fungal infections in otherwise healthy human hosts known to da...
In a retrospective view,this review examines the impact of mucormycosis on health workers and researchers during the COVID era.The diagnostic and treatment challenges arising from unestablished underlying pathology an...
supported by the National Natural Science Foundation of China(81790631);the National Key Research and Development Program of China(2022YFC3602000);the Shandong Provincial Laboratory Project(SYS202202);Research Project of Jinan Micro-ecological Biomedicine Shandong Laboratory(JNL-2022009B,JNL-2022047D)。
Liver disease,a major health concern worldwide,is a serious and progressive disorder.Herein,we not only established a mouse model of DEN+CCl4-induced primary liver disease but also collected clinical human samples to ...
BACKGROUND Due to development of an immune-dysregulated phenotype,advanced liver disease in all forms predisposes patients to sepsis acquisition,including by opportunistic pathogens such as fungi.Little data exists on...
co-financed by the NSFC(81991524,81991523,and 22193071,China);MOST grants(STI2030-Major Project-2022ZD0211804,China).
Peptides are a particular molecule class with inherent attributes of some small-molecule drugs and macromolecular biologics,thereby inspiring continuous searches for peptides with therapeutic and/or agrochemical poten...
Background:Infectious keratitis is a major cause of global blindness.We tested whether standalone photoactivated chromophore corneal cross-linking(PACK-CXL)may be an efective frst-line treatment in early to moderate i...