Supported by Liaoning Provincial Science and Technology Plan Joint Plan,No.2023JH2/101700149。
BACKGROUND The deleterious effects of surgical trauma and subsequent postoperative complications pose significant challenges to the smooth recovery of patients after gastric cancer(GC)resection despite the substantial...
Supported by the National Key Research and Development Program of China,No.2023YFF1204702;the National Natural Science Foundation of China,No.82173151;Capital’s Funds for Health Improvement and Research,No.CFH 2022-4-1025;Beijing Hospitals Authority Clinical Medicine Development of Special Funding,No.XMLX202119;Science Foundation of Peking University Cancer Hospital,No.PY202329.
BACKGROUND Gastric mixed-adenoneuroendocrine carcinoma(G-MANEC)is a subtype of gastric cancer.Building upon prior research findings,we propose that tumours containing both neuroendocrine carcinoma(NEC)and adenocarcino...
BACKGROUND The prevalence and mortality rates of gastric carcinoma are disproportionately elevated in China,with the disease's intricate and varied characteristics further amplifying its health impact.Precise forecast...
We discuss the findings of Wu et al on the utility of neutrophil-to-lymphocyte ratio,platelet-to-lymphocyte ratio,and systemic immune-inflammatory index as diagnostic markers for gastric carcinoma(GC).We commend the s...
BACKGROUND The diagnosis of gastric carcinoma(GC)is essential for improving clinical outcomes.However,the biomarkers currently used for GC screening are not ideal.AIM To explore the diagnostic implications of the neut...
The editorial discusses the impact of liver metastasis on immunotherapy efficacy in gastric cancer(GC)patients.Liver metastasis can hinder the effectiveness of immunotherapy by altering the immune microenvironment,lea...
BACKGROUND Although chemotherapy is effective for treating advanced gastric carcinoma(aGC),it may lead to an adverse prognosis.Establishing a highly effective and low-toxicity chemotherapy regimen is necessary for imp...
supported by grants from The Natural Science Foundation of Anhui Province,China(No.1908085QH333);the Key Research and Development Project of Anhui Province,China(No.202004j07020044);the Natural Science Research Project of Anhui Provincial University(China)(No.KJ2018ZD019);Foundation of Beijing Life Oasis Public Service Center(China)(No.cphcf-2022-021).
Neutrophils constitute a significant portion of the immune cells present within the tumor microenvironment.Evidence generated by our group has confirmed neutrophils to be an adverse independent prognostic factor affec...
supported by the National Natural Science Foundation of China (No. U20A20371);the National Key Technology Research and Development Program of the Ministry of Science and Technology of China (No. D171100006517004);Beijing Municipal Administration of Hospitals’ Youth Program (QML20191103);Clinical Medicine Plus X-Young Scholars Project, Peking University;the Fundamental Research Funds for the Central Universities and the Science Foundation of Peking University Cancer Hospital。
Objective: Positive peritoneal lavege cytology(CY1) gastric cancer is featured by dismal prognosis, with high risks of peritoneal metastasis. However, there is a lack of evidence on pathogenic mechanism and signature ...
This work was supported by the grants from the Jiangxi Province Key Research and Development Program(No.20203BBG73056);the Jiangxi Province Academic and Technical Leaders Training Program for Major Disciplines(Leading Talents Program:20213BCJ22014);the National Natural Science Foundation of China(Nos.82160475 and 82360591).
Invasion and metastasis are the leading causes of death in individuals with malignant tumors,including gastric cancer.In this study,we aim to explore the effect and related mechanisms of methionine restriction(MR)on g...