Supported by the National Natural Science Foundation of China(No.81070735)
AIM: To evaluate the effects of lentivirus-mediated pigment epithelium-derived factor (PEDF) gene transfer performed in treatment of rats with established choroidal neovascularization (CNV), and investigates the mecha...
Supported by National Natural Science Foundation(No.30572011);Natural Science Foundation of Shandong Province(No.ZR2010HQ041)
AIM: To transfect the cat corneal endothelial cells (CECs) with recombinant human β-nerve growth factor gene adeno-associated virus (AAV-β-NGF) and to observe the effect of the expressed β-NGF protein on the p...
Supported by Natural Science Foundation of China(No.30901395);the Doctoral Fund of Ministry of Education of China(No.20090142120012,20110142120021)
AIM: To investigate whether the enhanced green fluorescent protein(EGFP) reporter gene could be transferred into human trabecular meshwork(HTM) cells by a HIV-based lentivirus both in vitro and ex vivo.METHODS: The HI...
National Natural Science Foundation of China (No. 81000393)
AIM: To investigate whether 15-Lipoxygenase-1 (15-LOX-1) plays an important role in the regulation of angiogenesis, inhibiting hypoxia-induced proliferation of retinal microvascular endothelial cells (RMVECs) and the ...
National Natural Science Foundation of China(No.30572011);Natural Science Foundation of Shandong Province,China(No.ZR2010HQ041)
AIM: To demonstrate that human platelet-derived growth factor-B (PDGF-B) cDNA could be Expressed in primary cultured cat corneal endothelia cells by using gene transfer techniques; to explore a useful tool for the fur...