GLUT2

作品数:67被引量:311H指数:11
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相关领域:医药卫生更多>>
相关作者:王修启冯定远谭会泽苏海林束刚更多>>
相关机构:山西农业大学华南农业大学武汉大学北京中医药大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划山西省青年科技研究基金广东省自然科学基金更多>>
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Apple polyphenol phloretin inhibits typeⅡglucose transporter and enhances anti-HER2 antibody drug binding as an adjuvant treatment for HER2-positive breast cancer
《Food Science and Human Wellness》2025年第4期1264-1280,共17页Han-Sheng Chang Tzu-Chun Cheng Shih-Hsin Tu Pei-Han Liao Yu-Ching Lee Chi-Tang Ho Min-Hsiung Pan Li-Ching Chen Yuan-Soon Ho 
supported by the Science and Technology Council,Taiwan,China(NSTC 112-2320-B-039-057 and MOST 111-2320-B-039-067-MY3);the China Medical University,Taiwan,China(CMU112-S-18),awarded to Yuan-Soon Ho;the China Medical University,Taiwan,China(CMU112-N-02),awarded to Li-Ching Chen;the Science and Technology Council,Taiwan,China(MOST 110-2320B-039-079)。
This study presents novel findings on the potential of phloretin,an apple polyphenol,to enhance the effectiveness of anti-human epidermal growth factor receptor-2(HER2)antibody therapy in HER2-positive breast cancer p...
关键词:TypeⅡglucose transporter(GLUT2) PHLORETIN Human epidermal growth factor receptor 2-intracellular domain(HER2-ICD) TRASTUZUMAB Trastuzumab-resistance 
茯苓多糖对糖尿病小鼠糖脂代谢和氧化应激紊乱的影响
《天然产物研究与开发》2025年第2期195-203,共9页张淑静 宁真真 
河南省高等学校重点科研项目(22B310006)。
研究茯苓多糖(Poria cocos polysaccharides,PCP)对C57BL/6J小鼠糖尿病模型中糖脂代谢和氧化应激的改善作用及其机制。通过喂食高脂肪食物结合链脲佐菌素(streptozotocin,STZ)注射诱导2型糖尿病(diabetes mellitus type 2,T2DM)模型,将...
关键词:茯苓多糖 糖尿病 糖脂代谢 氧化应激紊乱 GLUT2/PI3K/AKT信号通路 
GLUT1、GLUT2介导的葡萄糖摄取对小鼠牙齿早期发育的影响
《口腔医学研究》2024年第10期920-927,共8页刘贞 许针针 相黎黎 崔颖颖 孙轶群 
目的:探究葡萄糖转运蛋白(glucose transporter,GLUT)1、GLUT2介导的葡萄糖摄取对小鼠牙齿早期发育的影响。方法:收集胚胎13.5 d(embryonic day 0.5,E13.5)、E14.5、E16.5、E18.5和出生后1 d(postnatal day 1,P1)时期的下颌磨牙牙胚、...
关键词:葡萄糖转运蛋白1 葡萄糖转运蛋白2 葡萄糖摄取 牙齿早期发育 根皮素 
Gedunin attenuates streptozotocin-induced diabetic hepatopathy in rats
《Asian Pacific Journal of Tropical Biomedicine》2024年第7期288-297,共10页Suchismita Mazumdar Thankamani M Marar Jyoti M Patki 
Objective:To examine the hepatoprotective effects of gedunin in streptozotocin(STZ)-induced diabetic rats.Methods:Rats were divided into 4 groups:control,STZ,gedunin,and STZ+gedunin.Biochemical parameters for liver fu...
关键词:Gedunin GLUT2 SGLT1 Diabetic hepatopathy DOCKING HISTOLOGY Homology modelling 
Flammulina velutipes polysaccharide-iron (Ⅲ) complex used to treat iron deficiency anemia after being absorbed via GLUT2 and SGLT1 transporters被引量:1
《Food Science and Human Wellness》2023年第5期1828-1840,共13页Chenying Shi Chen Cheng Xiaotong Lin Yanfang Qian Yufeng Du Guitang Chen 
supported by the State key research and development plan “Modern food processing and food storage and transportation technology and equipment” (2017YFD0400203)。
Iron deficiency anemia(IDA)is a common nutritional problem, but traditional iron supplements cause many adverse reactions. Thus, the development of a novel iron supplement might be significant for the treatment of IDA...
关键词:Flammulina velutipes polysaccharide Iron deficiency anemia Iron supplement Caco-2 cell model Gut microbiota 
育雏温度对雏鸡卵黄囊脂肪酸吸收和肠道发育及代谢相关基因 GLUT2和PepT1 表达的影响
《南京农业大学学报》2023年第5期913-921,共9页赵羽彤 陈兴勇 刘政权 常鹏辉 彭锦州 吉倩昀 
安徽省重点研发计划项目(202104f06020037)。
[目的]本文旨在探究早期育雏温度对雏鸡卵黄囊吸收和肠道发育的影响。[方法]选取1日龄健康淮南麻黄鸡雏鸡189只,随机均分为3组,育雏温度分别为33、30和27℃(2.5 d后3组育雏温度统一为33℃),每组3个重复,每个重复21只。分别于0.5、1、1.5...
关键词:淮南麻黄鸡 育雏温度 卵黄囊 脂肪酸吸收 绒隐比 肠道发育 
桑芪益气养阴方对胰岛素抵抗大鼠肝脏ACC1/FASN/SCD1信号通路及GLUT2的影响
《环球中医药》2023年第7期1294-1300,共7页李丽 刘佳琪 冯颖童 扈觐玺 姜斯佳 高晶 贾岚 王景霞 
国家重点研发计划(2018YFC1706803)。
目的研究桑芪益气养阴方对胰岛素抵抗大鼠肝脏组织乙酰辅酶A羧化酶1(Acetyl-coa carboxylase 1,ACC1)/脂肪酸合成酶(fatty acid synthase,FASN)/硬脂酰-辅酶A去饱和酶1(stearoyl-CoA desaturase 1,SCD1)通路及葡萄糖转运蛋白2(glucose t...
关键词:桑芪益气养阴方 气阴两虚证 胰岛素抵抗 氧化应激 肝脏糖脂代谢 
GnT-IVa对京尼平苷调节胰腺β细胞GLUT2糖基化及葡萄糖摄取的影响被引量:1
《重庆理工大学学报(自然科学)》2023年第5期324-330,共7页李维钊 申甚莉 边阳萍 赵婉均 汪夏 殷菲 
重庆市科技计划重点项目(cstc2017jcyjBX0077);重庆市高校优秀创新团队项目(CXTDX201601031)。
N-乙酰氨基葡萄糖转移酶-4a(N-acetylglucosamine transferase-4a,GnT-IVa)是胰岛β细胞中葡萄糖转运蛋白2(glucose transporter 2,GLUT2)形成N-糖链分支复合物、使其驻留在细胞膜表面完成正常生理功能所必需的糖基转移酶。课题组前期...
关键词:京尼平苷 N-乙酰氨基葡萄糖转移酶-4a 糖基化 葡萄糖摄取 
Cinnamon free phenolic extract regulates glucose absorption in intestinal cells by inhibiting glucose transporters
《Food Bioscience》2023年第2期479-487,共9页Yaoyao Liu Daorui Pang Dongxu Xing Weifei Wang Qian Li Sentai Liao Erna Li Yuxiao Zou 
We acknowledge the Agricultural Competitive Industry Discipline Team Building Project of Guangdong Academy of Agricultural Sciences(202119TD);the Excellent Doctors Foundation of Guangdong Academy of Agricultural Sciences(R2021YJ-YB1002);the Guidance for Young Scientist of Guangdong Academy of Agricultural Sciences(R2020QD-043);the Innovative Research Team Construction Project for Modern Agricultural Industry Common Key Technologies of Guangdong Province(2022KJ117)for financial support.
Cinnamon is a traditional herbal medicine that is a valuable source of bioactive phenolic compounds.In this study,we determined the effects of cinnamon free phenolic extract(CFPE)on glucose transport in Caco-2 cells a...
关键词:Cinnamon free phenolic extract Glucose uptake and transport SGLT1 GLUT2 
PXR activation impairs hepatic glucose metabolism partly via inhibiting the HNF4α-GLUT2 pathway被引量:2
《Acta Pharmaceutica Sinica B》2022年第5期2391-2405,共15页Peihua Liu Ling Jiang Weimin Kong Qiushi Xie Ping Li Xiaonan Liu Jiayi Zhang Ming Liu Zhongjian Wang Liang Zhu Hanyu Yang Ying Zhou Jianjun Zou Xiaodong Liu Li Liu 
supported by the National Natural Science Foundation of China (Nos.81673505,81872930,and 82073922);the “Double First-Class” university project (No.CPU2018GY22,China);“333” Project of Jiangsu Province (No.BRA2020287,China)。
Drug-induced hyperglycemia/diabetes is a global issue. Some drugs induce hyperglycemia by activating the pregnane X receptor(PXR), but the mechanism is unclear. Here, we report that PXR activation induces hyperglycemi...
关键词:Pregnane X receptor Hepatocyte nuclear factor4-alpha Glucose transporter 2 Hepatic glucose uptake Diabetes Drug-induced hyperglycemia 
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