National Natural Science Foundation of China,Grant/Award Number:82101937;Guangdong Medical Science and Technology Research Fund Project,China,Grant/Award Number:B2024069;Guangzhou Science and Technology Plan Project,China,Grant/Award Number:2024A04J4923 and SL2023A04J02229。
Background:Makorin ring finger protein 3 gene(MKRN3)gene mutation is the most common genetic cause of central precocious puberty(CPP)in children.Due to the lack of ideal MKRN3-modified animal model(MKRN3-modified mice...
supported by the National Natural Science Foundation of China(NSFC,31971413)to DL and NSFC(31770445)to YW;the Natural Science Foundation of Hebei Province,China(NSFHB,C2020205038)to DL and NSFHB(C2020205005);the Postdoctoral Research Foundation of China(PRFC,2020M670685)to LW。
The hypothalamic-pituitary-gonadal(HPG)axis ubiquitously regulates seasonal reproduction,following the rhythmicity of a suite of environmental cues.Birds display prominent seasonal variations in gonad size regulated b...