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GOV: 作品数：404被引量：3412H指数：32; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：欧阳昭连张婷陈娟杜可明沈伟更多>>; 相关机构：中国医学科学院北京协和医学院复旦大学中国人民解放军总医院北京大学第一医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国博士后科学基金更多>>

医疗器械临床试验注册特点研究被引量：5: 《中国医疗设备》2018年第10期113-118,131,共7页张婷陈娟池慧欧阳昭连; 国家重点研究发展计划(2016YFC0104805);中国医学科学院中央级公益性科研院所基本科研业务费专项(2017PT63006);中国医学科学院中央级公益性科研院所基本科研业务费专项(2017PT63005); 通过对医疗器械临床试验数据进行采集、分析,采用文献计量学的方法,从注册数量、适应症、申办机构、试验分期等角度来评价医疗器械领域行业活力。研究结果显示,全球医疗器械临床试验注册共有33127项,中国有1182项;美国和欧洲是主要开展...; 关键词：ClinicalTrials.gov平台医疗器械临床试验注册特点行业活力

Single Cell HLA Matching Feasibility by Whole Genomic Amplification and Nested PCR: 《Chinese Medical Sciences Journal》2004年第3期198-198,共1页Xiao-hongLi Fang-yinMeng; SupportedbytheNationalNaturalScienceFoundationofChina(30170394)andtheSpecialFundforPromotionofEducation;MinistryofSienceP.R.C(985)and"973"FoundationofChina(001cb51010201).; 关键词：Alleles Gene Amplification Genome GENOTYPE HLA-A Antigens HLA-B Antigens Humans Polymerase Chain Reaction Research Support Non-U.S. Gov't

Three new alternative splicing variants of human cytochrome P450 2D6 mRNA in human extratumoral liver tissue被引量：2: 《World Journal of Gastroenterology》2004年第22期3356-3360,共5页JianZhuge Ying-NianYu; Supported by the National Key Basic Research and Development Program of China,No.2002CB512901;National Natural Science Foundation of China,No.39770868 and Natural Science Foundation of Zhejiang Province,No.397490; AIM: To identify the new alternative splicing variants of human CYP2D6 in human extratumoral liver tissue with RT-PCR and sequencing. METHODS: Full length of human CYP2D6 cDNAs was amplificated by reverse transcriptio...; 关键词：Alternative Splicing Base Sequence Carcinoma Hepatocellular Cytochrome P-450 CYP2D6 DNA Complementary EXONS Humans Liver Liver Neoplasms Molecular Sequence Data Mutation RNA Messenger Research Support Non-U.S. Gov't Reverse Transcriptase Polymerase Chain Reaction

Hepatic differentiation from embryonic stem cells in vitro被引量：7: 《Chinese Medical Journal》2003年第12期1893-1897,共5页胡安斌蔡继业郑启昌何晓青潘运龙李凌松; ThisworkwassupportedbytheNationalKeyResearchFoundationofChina ( 973 ) (No 2 0 0 1CB5 10 10 1)andtheNationalNaturalScienceFoundationofChina (No 3 0 2 3 0 3 5 0 ;No 60 2 780 14 ); OBJECTIVE: To investigate an method for hepatic differentiation from embryonic stem cells (ES cells) in vitro and the resulting differentiation ratio, in order to develop a procedure for producing a new type of hepato...; 关键词：Animals Cell Differentiation Cells Cultured EMBRYO HEPATOCYTES Liver MICE Mice Inbred BALB C Research Support Non-U.S. Gov't Stem Cells

Sensory evoked potentials in patients with affective disorders accompanying suicidal behavior被引量：2: 《Chinese Medical Journal》2002年第11期1675-1678,152,共4页王红星白培深陈兴时尹岭; ThestudywassupportedbyNationalKeyProgramforBasicResearchofChina (No .2 0 0 1CCA0 0 70 0 ); OBJECTIVE: To investigate the variations of sensory evoked potentials (SEPs) in patients with affective disorders accompanying suicidal behavior. METHODS: 39 depressive patients, 22 manic patients and 33 normal contro...; 关键词：Evoked Potentials Auditory Evoked Potentials Somatosensory Evoked Potentials Visual Suicide Attempted Adult Bipolar Disorder Depressive Disorder Female Humans Male Middle Aged Research Support Non-U.S. Gov't

Experimental studies on the treatment and pathological basis of combined radiation and burn injury被引量：1: 《Chinese Medical Journal》2002年第12期1763-1766,共4页程天民陈宗荣阎永堂冉新泽粟永萍艾国平; ThisstudywassupportedinpartbytheNationalBasicResearchandPrioritiesProgram (No G19990 5 42 0 5); OBJECTIVE: To investigate therapeutics for and the pathological basis of combined radiation and burn injuries. METHODS: Combined radiation and burn injuries on mice and rats were inflicted by gamma ray irradiation fro...; 关键词：ANIMALS BURNS Calcium Heart HEMATOPOIESIS Mice Radiation Injuries RATS Rats Wistar Research Support Non-U.S. Gov't

Decline in the expression of IL-2 after trauma and changes in the nuclear transcription factors NFAT and AP-1被引量：1: 《Chinese Medical Journal》2002年第9期1348-1351,150,共4页罗艳梁华平胡承香徐祥王正国; ThisworkwassupportedbytheNationalBasic"973ResearchProgramofChina (G19990 5 42 0 3)andthegrantfromtheNationalNaturalScienceFoundationofChina (No 3 9870 82 8); OBJECTIVE: To investigate whether the decrease in expression of interleukin-2 (IL-2) after trauma is associated with changes in DNA binding activity of nuclear factor of activated T cells (NFAT) and activator protein-...; 关键词：Nuclear Proteins Animals Cell Nucleus DNA DNA-Binding Proteins Electrophoretic Mobility Shift Assay Female INTERLEUKIN-2 Male Mice NFATC Transcription Factors Proto-Oncogene Proteins c-fos Proto-Oncogene Proteins c-jun RNA Messenger Research Support Non-U.S. Gov't Transcription Factor AP-1 Transcription Factors

Epstein-Barr virus induces human nasopharyngeal epithelial cells to escape from the replicative senescence被引量：1: 《Chinese Medical Journal》2002年第6期803-809,146,共7页杨静唐发清顾焕华邓锡云翁新宪唐敏曹亚; grantsfromStateKeyProgramofBasicResearch (G19980 5 12 0 1)andNationalScienceFundforDistinguishedYoungScholars (No . 395 2 5 0 0 2 2 )fromNationalNaturalScienceFoundationofChina ;andCMB (No .96 6 5 5 )fromtheChinaMedicalBoardofNewYork ;USA; OBJECTIVE: To observe the biological changes of primary human nasopharyngeal epithelial cells in the early stage of immortalization. METHODS: The morphological changes of nasopharyngeal epithelial cells were observed ...; 关键词：Cell Aging Cell Transformation Viral Cyclin-Dependent Kinase Inhibitor p16 Epithelial Cells Herpesvirus 4 Human Humans NASOPHARYNX Research Support Non-U.S. Gov't Tetradecanoylphorbol Acetate

Linkage analysis of a region on chromosome 2 with essential hypertension in Chinese families被引量：2: 《Chinese Medical Journal》2002年第5期654-657,146,共4页朱鼎良王厚义熊墨淼初少莉金力王谷亮何鑫袁文涛钱岳晟赵光胜黄薇; supported by grants of“Chinese High Tech Program(863)”(102-10-02-03，Z19-01-03-01A)；“National Key Program on Basic Research(973)”(G19980510)from the Ministry of Science and Technology，China．; OBJECTIVE: To verify the linkage of the candidate regions identified in a previous study (markers D2S168, D2S151, D2S142 on chromosome 2) with hypertension in Chinese families. METHODS: A genetic linkage study focused...; 关键词：Alleles China Chromosomes Human Pair 2 Family Health Female Gene Frequency Humans HYPERTENSION Linkage (Genetics) Linkage Disequilibrium Male Microsatellite Repeats Research Support Non-U.S. Gov't

Plating densities, alpha-difluoromethylornithine effects and time dependence on the proliferation of IEC-6 cells被引量：1: 《Chinese Medical Journal》2002年第4期518-520,共3页张予理陈蔚文; 国家重点基础研究发展计划(973计划)，国家自然科学基金; OBJECTIVE: To characterize the role of plating densities and alpha-difluoromethylornithine (DFMO) on the proliferation of IEC-6 cells in vitro. METHODS: IEC-6 cells were seeded in 96-well microplates at various densit...; 关键词：Animals Antineoplastic Agents Cell Count Cell Division Cell Line EFLORNITHINE Research Support Non-U.S. Gov't Time Factors

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