the Clinical Research Plan of SHDC(No.SHDC2020CR2016B);the Scientific Innovation Project of Shanghai Education Committee(No.2021-01-07-00-07-E00080);the National Natural Science Foundation of China(No.81902568).
This study compared different doublet and triplet therapies for efficacy and safety in metastatic hormone-sensitive prostate cancer(mHSPC).PubMed,EMBASE,and the Cochrane Library were comprehensively searched for eligi...
supported by the National Natural Science Foundation of China(No.82172785,82103097,81974398,81902577,and 81872107);the Science and Technology Support Program of Sichuan Province(2021YFS0119);the 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(No.0040205301E21)。
To report the regional locations of metastases and to estimate the prognostic value of the pattern of regional metastases inmen with metastatic hormone-sensitive prostate cancer (mHSPC), we retrospectively analyzed 87...
ARASENS is an international phase III trial demonstrating the beneficial role of darolutamide,a novel antiandrogen,when added to docetaxel and androgen deprivation therapy(ADT),with improvement in overall survival in ...
Follicle-stimulating hormone(FSH)represents a therapeutic option in normogonadotropic patients with idiopathic oligozoospermia.The aim of this review was to evaluate the possible dose-and drug-dependent efficacy of FS...
Anti-Mullerian hormone(AMH)is a functional marker of fetal Sertoli cells.The germ cell number in adults depends on the number of Sertoli cells produced duri ng peri natal development.Rece ntly,AMH has received increas...
CHAARTED was an ECOG-led phase III trial looking at early chemotherapy with the use of docetaxel in addition to androgen deprivation therapy (ADT) versus ADT alone in hormone-sensitive prostate cancer. The positive ...
Hormone naive advanced prostate cancer is subdivided into two disease states: biochemical recurrence and traditional M 1 (metastatic) prostate cancer and characterized by no prior hormonal therapy or androgen depri...
Male reproductive function is impaired during end-stage renal disease (ESRD). Disturbance of the hypothalamic-pituitary-gonadal axis, and therefore the regulation of sex hormones, is one of the major causes. Our foc...
In a recent publication appearing in the Asian Journal of Andrology, a team of researchers investigated the relationship of early hormone exposure to adult lung function. In the publication, 'Second to fourth digit r...
Assays that measure steroid hormones in patient care, public health, and research need to be both accurate and precise, as these criteria help to ensure comparability across all clinical and research applications. Thi...