HYPOXIC

作品数:306被引量:941H指数:15
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相关领域:医药卫生更多>>
相关作者:谭双香戴爱国胡瑞成丁艳洁蒋犁更多>>
相关机构:首都医科大学南华大学北京大学第一医院中国医科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Ultrasound cascade regulation of nano-oxygen hybrids triggering ferroptosis augmented sonodynamic anticancer therapy
《Nano Research》2023年第5期7280-7292,共13页Yue Sun Yihui Wang Ruyin Han Ziwei Ren Xin Chen Wenzhuo Dong Stephen Choi Quanhong Liu Xiaobing Wang 
the Fundamental Research Funds for the Central Universities(No.GK202105004).
Sonodynamic therapy(SDT)has attracted great interest in the field of cancer therapy because of its non-invasiveness,deep penetration,spatiotemporal controllability.However,the sonodynamic effect is severely hindered b...
关键词:sonodynamic therapy nano-oxygen carrier sono-Fenton ferroptosis hypoxic tumor environment 
The relief of hypoxic microenvironment using an O_(2) self-sufficient fluorinated nanoplatform for enhanced photodynamic eradication of bacterial biofilms被引量:2
《Nano Research》2022年第2期1636-1644,共9页Lingyun Zou Dengfeng Hu Fanjin Wang Qiao Jin Jian Ji 
supported by National Key Research and Development Project(No.2020YFE0204400);National Natural Science Foundation of China(No.52022090);Zhejiang Provincial Ten Thousand Talents Program(No.2018R52001).
Hypoxia,an important characteristic of bacterial biofilms,can hinder the generation of reactive oxygen species(ROS)in photodynamic therapy(PDT),leading to reduced therapeutic efficacy of PDT.In order to address this i...
关键词:biofilm hypoxia perfluorohexane LIPOSOME photodynamic therapy 
Cyanobacteria-based near-infrared light-excited self-supplying oxygen system for enhanced photodynamic therapy of hypoxic tumors被引量:6
《Nano Research》2021年第3期667-673,共7页Yinghua Zhang Huifang Liu Xinyue Dai Hang Li Xiaohan Zhou Shizhu Chen Jinchao Zhang Xing-Jie Liang Zhenhua Li 
This work was supported by National Natural Science Foundation of China(Nos.21977024,21601046,and 31971304);Advanced Talents Incubation Program of the Hebei University(No.801260201020);Funded by China Postdoctoral Science Foundation(No.2019M650558);Beijing Postdoctoral Research Foundation and Beijing Chaoyang District Postdoctoral Research Fundation.We are grateful to Medical Comprehensive Experimental Center of Hebei University for the animal experiment.
Tumor hypoxia has been considered to induce tumor cell resistance to radiotherapy and anticancer chemotherapy,as well as predisposing for increased tumor metastases.Therefore,strategies for the eradication of the hypo...
关键词:self-supplying oxygen CYANOBACTERIA hypoxic tumor photodynamic therapy upconversion nanoparticles 
Rod-shape inorganic biomimetic mutual-reinforcing MnO2-Au nanozymes for catalysis-enhanced hypoxic tumor therapy被引量:6
《Nano Research》2020年第8期2246-2258,共13页Lifang Yang Chuchu Ren Min Xu Yilin Song Qianglan Lu Yule Wang Yan Zhu Xinxing Wang Nan Li 
This work was supported by Young Elite Scientists Sponsorship Program by Tianjin(No.0701320001);this work was partially supported by the grants of the National Natural Science Foundation of China(Nos.31971106 and 81372124).
Biomimetic nanozymes possessing natural enzyme-mimetic activities have been extensively applied in nanocatalytic tumor therapy.However,engineering hybrid biomimetic nanozymes to achieve superior nanozyme activity rema...
关键词:nanozyme self-supplied mutual-reinforcing HYPOXIA catalysis-enhanced therapy 
Gold nanoparticles doped metal-organic frameworks as near-infrared light-enhanced cascade nanozyme against hypoxic tumors被引量:7
《Nano Research》2020年第3期653-660,共8页Xinli Liu Yongchun Pan Jingjing Yang Yanfeng Gao Ting Huang Xiaowei Luan Yuzhen Wang Yujun Song 
This work was financially supported by the National Natural Science Foundation of China(Nos.21874066,81601632 and 61804076);the Natural Science Foundation of Jiangsu Province(Nos.BK20160616 and BK20180700);the Fundamental Research Funds for Central Universities,the Shuangchuang Program of Jiangsu Province,and the Thousand Talents Program for Young Researchers.
We report gold nanoparticles(AuNPs)doped iron-based metal-organic frameworks(GIM)which displays near-infrared light(NIR)-enhanced cascade nanozyme against hypoxic tumors.Due to the strong protein adsorption-induced su...
关键词:nanozyme metal-organic frameworks gold nanoparticles near-infrared light reactive oxygen species 
Inhibition of hypoxia-inducible factor 1 with acriflavine sensitizes hypoxic tumor cells to photodynamic therapy with zinc phthalocyanine-encapsulating cationic liposomes被引量:4
《Nano Research》2016年第6期1639-1662,共24页Mans Broekgaarden Ruud Weijer Massis Krekorian Bas van den IJssel Milan Kos Lindy K. Alles Albert C. van Wijk1 Zsolt Bikadi Eszter Hazai Thomas M. van Gulik Michal Heger 
Photodynamic therapy (PDT) is a tumor treatment modality in which a tumor- localized photosensitizer is excited with light, which results in local production of reactive oxygen species, destruction of tumor vasculat...
关键词:cancer therapy confocal microscopy drug delivery system glucose metabolism HYPOXIA 
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