the Fundamental Research Funds for the Central Universities(No.GK202105004).
Sonodynamic therapy(SDT)has attracted great interest in the field of cancer therapy because of its non-invasiveness,deep penetration,spatiotemporal controllability.However,the sonodynamic effect is severely hindered b...
supported by National Key Research and Development Project(No.2020YFE0204400);National Natural Science Foundation of China(No.52022090);Zhejiang Provincial Ten Thousand Talents Program(No.2018R52001).
Hypoxia,an important characteristic of bacterial biofilms,can hinder the generation of reactive oxygen species(ROS)in photodynamic therapy(PDT),leading to reduced therapeutic efficacy of PDT.In order to address this i...
This work was supported by National Natural Science Foundation of China(Nos.21977024,21601046,and 31971304);Advanced Talents Incubation Program of the Hebei University(No.801260201020);Funded by China Postdoctoral Science Foundation(No.2019M650558);Beijing Postdoctoral Research Foundation and Beijing Chaoyang District Postdoctoral Research Fundation.We are grateful to Medical Comprehensive Experimental Center of Hebei University for the animal experiment.
Tumor hypoxia has been considered to induce tumor cell resistance to radiotherapy and anticancer chemotherapy,as well as predisposing for increased tumor metastases.Therefore,strategies for the eradication of the hypo...
This work was supported by Young Elite Scientists Sponsorship Program by Tianjin(No.0701320001);this work was partially supported by the grants of the National Natural Science Foundation of China(Nos.31971106 and 81372124).
Biomimetic nanozymes possessing natural enzyme-mimetic activities have been extensively applied in nanocatalytic tumor therapy.However,engineering hybrid biomimetic nanozymes to achieve superior nanozyme activity rema...
This work was financially supported by the National Natural Science Foundation of China(Nos.21874066,81601632 and 61804076);the Natural Science Foundation of Jiangsu Province(Nos.BK20160616 and BK20180700);the Fundamental Research Funds for Central Universities,the Shuangchuang Program of Jiangsu Province,and the Thousand Talents Program for Young Researchers.
We report gold nanoparticles(AuNPs)doped iron-based metal-organic frameworks(GIM)which displays near-infrared light(NIR)-enhanced cascade nanozyme against hypoxic tumors.Due to the strong protein adsorption-induced su...
Photodynamic therapy (PDT) is a tumor treatment modality in which a tumor- localized photosensitizer is excited with light, which results in local production of reactive oxygen species, destruction of tumor vasculat...