IIB

作品数：76被引量：143H指数：6
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Engineering high amylose and resistant starch in maize by CRISPR/Cas9-mediated editing of starch branching enzymes被引量：1
《The Crop Journal》2024年第4期1252-1258,共7页Mingzheng Ma Shanqiu Sun Jinjie Zhu Xiantao Qi Gaoke Li Jianguang Hu Chuanxiao Xie Changlin Liu 
supported by the National Key Research and Development Program of China(2023YFD1202901);the China Agriculture Research System of MOF and MARA(CARS-02-06);the Key Area Research and Development Program of Guangdong Province(2018B020202008).
To improve the amylose content(AC)and resistant starch content(RSC)of maize kernel starch,we employed the CRISPR/Cas9 system to create mutants of starch branching enzyme I(SBEI)and starch branching enzyme IIb(SBEIIb)....
关键词：MAIZE Gene editing Starch branching enzyme I Starch branching enzyme IIb 
Clinical Effect of Tislelizumab Combined with Chemotherapy in the Treatment of Stage IIIb-IV Non-Small Cell Lung Cancer
《Proceedings of Anticancer Research》2024年第4期98-103,共6页Jie Jiang 
Objective:To analyze the therapeutic effect of tislelizumab combined with chemotherapy in patients with stage IIIb-IV non-small cell lung cancer(NSCLC).Methods:A total of 50 patients with stage IIIb-IV NSCLC admitted ...
关键词：Tislelizumab CHEMOTHERAPY Stage IIIb-IV Non-small cell lung cancer 
Insights into the emergence and evolution of monkeypox virus:Historical perspectives,epidemiology,genetic diversity,transmission,and preventative measures被引量：1
《Infectious Medicine》2024年第2期1-9,共9页Smriti Krishna Chhaya Kurrey Manisha Yadav Shakuntala Mahilkar Subash Chandra Sonkar Naveen Kumar Vishvakarma Anand Sonkar Lal Chandra Bidhan Chandra Koner 
In 2022,just before the COVID-19 pandemic ended,many countries noticed a viral monkeypox outbreak.Monkeypox virus,a zoonotic pathogen,causes a febrile illness in humans and resembles smallpox.Prevention strategies enc...
关键词：ORTHOPOXVIRUS Monkeypox outbreak 2022 Clade IIb TRANSMISSION Vaccines 
Neutrophil extracellular traps induced by interleukin 8 via CXCR1/2 promote the progression of gastric carcinoma through transcription factor IIB-related factor 1 and cyclin被引量：2
《Genes & Diseases》2024年第2期575-578,共4页Qianling Wang Yiyin Zhang Wenxi Ding Cheng Feng Yuyan Wang Xiaoli Wei Ziting Qu Hui Wang Xiaoying Liu Hua Wang Kangsheng Gu 
supported by grants from The Natural Science Foundation of Anhui Province,China(No.1908085QH333);the Key Research and Development Project of Anhui Province,China(No.202004j07020044);the Natural Science Research Project of Anhui Provincial University(China)(No.KJ2018ZD019);Foundation of Beijing Life Oasis Public Service Center(China)(No.cphcf-2022-021).
Neutrophils constitute a significant portion of the immune cells present within the tumor microenvironment.Evidence generated by our group has confirmed neutrophils to be an adverse independent prognostic factor affec...
关键词：invasion gastric PROGRESSION 
Mucopolysaccharidosis typeⅢB:a current review and exploration of the AAV therapy landscape被引量：1
《Neural Regeneration Research》2024年第2期355-359,共5页Courtney J.Rouse Victoria N.Jensen Coy D.Heldermon 
supported by Sanfilippo Children’s Foundation;Sanfilippo Fundacja;Sanfilippo Initiative;Cure Sanfilippo;Lacerta Therapeutics;NIH/NINDS R01NS102624(to CDH)。
Mucopolysaccharidoses typeⅢB is a rare genetic disorder caused by mutations in the gene that encodes for N-acetyl-alpha-glucosaminidase.This results in the aggregation of heparan sulfate polysaccharides within cell l...
关键词：adeno-associated virus central nervous system gene therapy heparan sulfate immune response mucopolysaccharidoses type IIIB N-acetyl-alpha-glucosaminidase newborn screening 
单增李斯特菌PTS系统转运蛋白IIB^(man)介导运动性和感染的功能研究被引量：1
《中国预防兽医学报》2023年第11期1179-1187,共9页张佳雪 陈绵绵 程丽丽 任耿佳 徐像文 鲁珂蓥 庄楠茜 孙静 宋厚辉 程昌勇 
浙江省自然科学基金(LQ20C180001、LY23C180002);国家自然科学基金(32002253、31972648、31872620);浙江农林大学创新训练项目(S202210341103);浙江省大学生科技创新活动计划暨新苗人才计划(2023R412020)。
为探究单增李斯特菌(LM)磷酸转移酶系统(PTS)转运蛋白IIB^(man)在LM生长、运动性及其生物学功能,本研究以LM EGD-e株基因组为模板,经PCR扩增iiB^(man)基因的上下游基因片段(不包含iiB^(man)基因),插入质粒pKSV7以构建缺失质粒;以LM EGD-...
关键词：单增李斯特菌 磷酸转移酶系统 IIB^(man)转运蛋白 运动性 感染 
胸腔镜肺叶切除术治疗老年IIb-IIIa期非小细胞肺癌的效果观察
《医药前沿》2023年第14期55-57,共3页王君 陆亚东 孙健飞 施臻 
目的:观察胸腔镜肺叶切除术治疗老年IIb-IIIa期非小细胞肺癌的效果。方法:选取张家港市第一人民医院2018年10月—2022年10月收治老年IIB-IIIa期非小细胞肺癌患者共91例,根据医生推荐及患者意愿分为对照组(n=40)与试验组(n=51)。其中对...
关键词：胸腔镜 肺叶切除术 老年 非小细胞肺癌 生活质量 
HDAC I/IIb selective inhibitor Purinostat Mesylate combined with GLS1 inhibition effectively eliminates CML stem cells被引量：1
《Bioactive Materials》2023年第3期483-498,共16页Qiang Qiu Linyu yang Yunyu Feng Zejiang Zhu Ning Li Li Zheng Yuanyuan Sun Cong Pan Huandi Qiu Xue Cui Wei He Fang Wang Yuyao Yi Minghai Tang Zhuang Yang Yunfan Yang Zhihui Li Lijuan Chen Yiguo Hu 
Fundamental Research Funds for the Central Universities(2021SCU12022 to L.Yang);the 1.3.5 Project for Disciplines of Excellence(to Z.Li and L.Chen);West China Hospital,Sichuan University,the National Natural Science Foundation of China(82104211 to L.Yang);National Natural Science Foundation of China(81541092 and 81770103 to Y.Hu).
Purinostat Mesylate(PM)is a novel highly selective and active HDAC I/IIb inhibitor,and the injectable formulation of PM(PMF)based on the compound prescription containing cyclodextrin completely can overcome PM’s poor...
关键词：Chronic myelogenous leukemia Leukemia stem cell Selective HDAC I/IIb inhibitor GLS1 Mouse model 
猴痘病毒进化及检测技术研究进展被引量：10
《江苏预防医学》2023年第1期1-7,共7页祁贤 
国家自然科学基金猴痘相关重要基础科学问题研究专项项目(82241067);江苏省自然科学基金面上项目(BK20191489);江苏省自然科学基金面上项目(BK20221413)。
猴痘病毒是与天花病毒近亲的一种正痘病毒。2022年,猴痘病毒在全球100多个国家引起暴发和流行,成为年度国际关注的突发公共卫生事件。与之前的暴发疫情相比,引发2022年疫情的猴痘病毒明显增强了对人体的适应性,传播范围持续扩大,导致全...
关键词：猴痘病毒 IIb-B1谱系 病毒进化 检测技术 
Ultra-bright near-infrared-IIb emitting Zn-doped Ag_(2)Te quantum dots for noninvasive monitoring of traumatic brain injury被引量：2
《Nano Research》2023年第2期2719-2727,共9页Yifei Zhou Biao Huang Shi-Hui Chen Shu-Lin Liu Mingxi Zhang Ran Cui 
supported by the National Natural Science Foundation of China(Nos.22174105 and 21974104);the National Key Research and Development(R&D)Program of China(No.2020YFA0908800);Large-scale Instrument and Equipment Sharing Foundation of Wuhan University.
The long-wavelength region of the near-infrared-IIb(NIR-IIb,1,500–1,700 nm)imaging window has become an ideal window for in vivo imaging due to the suppressed photon scattering and near-zero autofluorescence of biolo...
关键词：near-infrared-IIb(NIR-IIb)window silver telluride quantum dots fluorescence in vivo imaging 
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