INTERLEUKIN-2

作品数：156被引量：353H指数：9
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相关作者：鲁亚玲许建峰段梅欣武永利魏雪红更多>>
相关机构：北京中医药大学中国科学技术大学中国科学院上海生命科学研究院宁夏医科大学更多>>
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Reduced interleukin-2 receptor subunitγexpression in Crohn's disease:A potential mechanism forγδT cell deficiency
《World Journal of Gastroenterology》2025年第13期152-154,共3页Md Sadique Hussain Ajay Singh Bisht Gaurav Gupta 
Crohn’s disease(CD)is a chronic inflammatory disorder characterized by dysregulated immune responses and significant disruption of intestinal immunity.A recent case-control study by Andreu-Ballester et al revealed de...
关键词：Crohn's disease Gastrointestinal immunology Interleukin-2 receptorγsubunit(CD132) Interleukin-7/interleukin-2 signaling pathway Immune regulation Immune signaling T cell apoptosis 
Role of relevant immune-modulators and cytokines in hepatocellular carcinoma and premalignant hepatic lesions被引量：6
《World Journal of Gastroenterology》2018年第11期1228-1238,共11页Abdel-Rahman N Zekri Somaya El Deeb Abeer A Bahnassy Abeer M Badr Mona S Abdellateif Gamal Esmat Hosny Salama Marwa Mohanad Ahmed Esam El-dien Shimaa Rabah Assmaa Abd Elkader 
AIM To assess the levels of different immune modulators in patients with hepatocellular carcinoma(HCC),in relation to other hepatic diseases.METHODS Eighty-eight patients were included in the current study and represe...
关键词：Hepatocellular carcinoma Hepatitis C virus NKG2D CD40 INTERLEUKIN-2 INTERLEUKIN-10 myeloid dendritic CELLS PLASMACYTOID CELLS natural killer cell CYTOKINES 
Expression of Interleukin-26 is upregulated in inflammatory bowel disease被引量：8
《World Journal of Gastroenterology》2017年第30期5519-5529,共11页Makoto Fujii Atsushi Nishida Hirotsugu Imaeda Masashi Ohno Kyohei Nishino Shigeki Sakai Osamu Inatomi Shigeki Bamba Masahiro Kawahara Tomoharu Shimizu Akira Andoh 
To investigate interleukin (IL)-26 expression in the inflamed mucosa of patients with inflammatory bowel disease (IBD) and the function of IL-26. METHODSHuman colonic subepithelial myofibroblasts (SEMFs) were isolated...
关键词：Inflammatory bowel disease Interleukin-26 MYOFIBROBLASTS 
Interleukin-28 and hepatitis C virus genotype-4:Treatment-induced clearance and liver fibrosis被引量：2
《World Journal of Gastroenterology》2012年第47期7003-7008,共6页Moutaz Derbala Nasser Rizk Fatima Shebl Saad Alkaabi Nazeeh Eldweik Anil John Manik Sharma Rafie Yaqoob Muneera Almohanadi Mohammed Butt Khaled Alejji 
Supported by Hamad Hospital-HMC and Qatar UniversityHealth Sciences-Biomedical Labs;sponsored by HMC
AIM:To investigate the association between interleukin-28B(IL28B) genotype and response to treatment and hepatic fibrosis in patients with hepatitis C virus(HCV) genotype 4.METHODS:Two hundred and one HCV-genotype 4 p...
关键词：Genotype 4 Hepatic fibrosis Hepatitis C virus Interleukin-28B rs12979860 
Unusual gastric and pancreatic metastatic renal cell carcinoma presentation 10 years after surgery and immunotherapy: A case report and a review of literature被引量：3
《World Journal of Gastroenterology》2006年第32期5234-5236,共3页Chiara Riviello Ilaria Tanini Greta Cipriani Pietro Pantaleo Carlo Nozzoli Alberto Poma Viligiardi Riccardo Andrea Valeri 
Renal cell carcinoma （RCC） is the most common renal tumor, accounting for 2%-3% of all malignancies. Though RCC is known to spread hematogenously, isolated RCC metastasis to the stomach is a rare event. In this arti...
关键词：Renal cell carcinoma Stomach metastasis Interleukin-2 treatment 
High efficient mammalian expression and secretion of a functional humanized single-chain Fv/human interleukin-2 molecules被引量：1
《World Journal of Gastroenterology》2006年第24期3859-3865,共7页Yue-Chun Shen Xue-HaoWang Xiao-Ming Wang Zao-Lai Chen Xi-Ping Shen Chao-Chen Zhao Jun Li 
AIM： To construct and produce a recombinant bispecific humanized single-chain Fv （sFv） /Interleukin-2 （IL-2） fusion protein by using mammalian cells. METHODS： The sFv/IL-2 protein was genetically engineered, and...
关键词：INTERLEUKIN-2 HUMANIZATION Antibody Fusion protein HER-2/NEU 
Interleukin-2 gene-encoded stromal cells inhibit the growth of metastatic cholangiocarcinomas被引量：6
《World Journal of Gastroenterology》2006年第12期1889-1894,共6页Myung-HwanKim Sang Soo Lee Sung Koo Lee Seung-Gyu Lee Chul-Won Suh Gyung-Yub Gong Jung-Sun Park Young-Hoon Kim Sang-Hee Kim 
Supported by The Asan Institute for Life Sciences of South Korea,No.2003-013
AIM： To demonstrate bone marrow stromal cells （BMSCs） can be used as an attractive target for genetic modification in the treatment of malignant diseases. METHODS： Using a hamster model of biliary cancer, we inves...
关键词：Bone marrow stromal cell Adenovirus/hIL-2 Biliary cancer 
Locoregional IL-2 low dose applications for gastrointestinal tumors被引量：1
《World Journal of Gastroenterology》2005年第35期5525-5529,共5页Zachary Krastev V Koltchakov R Tomova S Deredjian A Alexiev D Popov B Tomov Jan-Willem Koten John Jacobs Willem Den Otter 
AIM： To explore the feasibility of local interleukin 2 （IL-2） in patients with different forms of abdominal cancer. This required experimentation with the time interval between IL-2 applications and the methods of ...
关键词：INTERLEUKIN-2 Local IL-2 therapy Gastrointestinalcancer 
Effects of selenium on peripheral blood mononuclear cell membrane fluidity,interleukin-2 production and interleukin-2 receptor expression in patients with chronic hepatitis被引量：9
《World Journal of Gastroenterology》2004年第23期3531-3533,共3页Shui-XiangHe BingWu Xin-MingChang Hong-XiaLi WenQiao 
AIM To study the effect of selenium on peripheral blood mononuclear cell (PBMC) membrane fluidity and immune function in patients with chronic hepatitis.METHODS: PBMCs were pretreated with selenium (1.156x 10.7 mol/L)...
关键词：外周血 单核细胞 膜流动性 白细胞介素-2 受体表达 慢性肝炎 肝脏 
mIL-2R,T cell subsets & hepatitis C被引量：25
《World Journal of Gastroenterology》2002年第2期298-300,共3页Chao-Pin Li Ke-Xia Wang Jian Wang,Department of Aetiology and Immunology,School of Medicine,Huainan University of Technology,Huainan 232001,Anhui Province,China Bo-Rong Pan,the Fourth Military Medical University 
the Youth Scientific Foundation of the Ministry of Coal Industry of China,No.96-072
AIM: To study the levels of membrane interleukin-2 receptor (mIL-2R) and T cell subsets in peripheral blood mononuclear cells (PBMC) from patients with hepatitis C and their role in the pathogenesis of hepatitis C. ME...
关键词：ADOLESCENT Adult Female Hepatitis C Humans IMMUNOHISTOCHEMISTRY Male Middle Aged Receptors  Interleukin-2 Research Support  Non-U.S. Gov't T-Lymphocyte Subsets 
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