ISCHEMIA-REPERFUSION

作品数:210被引量:1347H指数:17
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相关领域:医药卫生更多>>
相关作者:张均田陈永红杜冠华张玲妹孙凤艳更多>>
相关机构:中国医学科学院北京协和医学院上海医科大学中国药科大学中国科学院上海生命科学研究院更多>>
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相关基金:国家自然科学基金中国博士后科学基金湖北省自然科学基金国家教育部博士点基金更多>>
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Effect of dexmedetomidine against liver ischemia-reperfusion injury in rats by reducing endoplasmic reticulum stress
《Journal of Hainan Medical University》2019年第5期10-13,共4页Quan-Sheng Wang Re-Ti Ai Fei-Fei Lu 
Objective:To investigate the effect of dexmedetomidine against liver ischemia-reperfusion injury in rats by reducing endoplasmic reticulum stress.Methods: A total of 24 adult male Sprague-Dawley rats were randomly div...
关键词:DEXMEDETOMIDINE LIVER Endoplasmic reticulum STRESS ISCHEMIA-REPERFUSION OXIDATIVE STRESS 
Effects of positive acceleration(+Gz stress) on liver enzymes,energy metabolism,and liver histology in rats被引量:1
《World Journal of Gastroenterology》2019年第3期346-355,共10页Bin Shi Xian-Qiang Wang Wei-Dong Duan Guo-Dong Tan Han-Jing Gao Ying-Wei Pan Qing-Jun Guo Hong-Yi Zhang 
BACKGROUND Exposure to high sustained +Gz(head-to-foot inertial load) is known to have harmful effects on pilots' body in flight. Although clinical data have shown that liver dysfunction occurs in pilots, the precise ...
关键词:Positive acceleration +GZ LIVER function ANIMAL models LIVER METABOLISM ISCHEMIA-REPERFUSION INJURY 
Remote ischemic preconditioning protects liver ischemia-reperfusion injury by regulating eNOS-NO pathway and liver microRNA expressions in fatty liver rats被引量:7
《Hepatobiliary & Pancreatic Diseases International》2017年第4期387-394,共8页Yun-Fei Duan Yong An Feng Zhu Yong Jiang 
supported by a grant from 2013 Applied Basic Research of Changzhou Bureau of Science and Technology(CJ20130044)
BACKGROUND: Ischemic preconditioning (IPC) is a strategy to reduce ischemia-reperfusion (I/R) injury. The protective effect of remote ischemic preconditioning (RIPC) on liver I/R injury is not clear. This study aimed ...
关键词:fatty liver ISCHEMIA-REPERFUSION remote ischemic preconditioning nitric oxide heat shock protein 70 endothelial nitric oxide synthase inducible nitric oxide synthase liver microRNA 
Role of nitric oxide in liver transplantation:Should it be routinely used?被引量:4
《World Journal of Hepatology》2016年第34期1489-1496,共8页Kyota Fukazawa John D Lang 
Ischemia-reperfusion injury (IRI) continues to be a major contributor to graft dysfunction, thus supporting the need for therapeutic strategies focused on minimizing organ damage especially with growing numbers of ext...
关键词:LIVER Nitric oxide ISCHEMIA-REPERFUSION NITRITE TRANSPLANTATION 
Ankaflavin ameliorates steatotic liver ischemiareperfusion injury in mice被引量:1
《Hepatobiliary & Pancreatic Diseases International》2015年第6期619-625,共7页Hao-Jun Yang Li-Ming Tang Xian-Ju Zhou Jun Qian Jie Zhu Ling Lu Xue-Hao Wang 
supported by grants from the International Collaboration Foundation of Jiangsu Province(BZ2011041);the Special Funds of Ministry of Health for Health Research(201302009);the National Natural Science Foundation of China(81273262)
BACKGROUND: It is well-known that steatotic liver is more susceptible to ischemia-reperfusion (I/R) injury during liver transplantation, liver resection and other liver surgeries. The increasing incidence of non-al...
关键词:ankaflavin ISCHEMIA-REPERFUSION Kupffer cells steatotic liver 
Sirtuin 1 in rat orthotopic liver transplantation:An I GL-1 preservation solution approach被引量:5
《World Journal of Gastroenterology》2015年第6期1765-1774,共10页Eirini Pantazi Mohamed Amine Zaouali Mohamed Bejaoui Emma Folch-Puy Hassen Ben Abdennebi Ana Teresa Varela Anabela Pinto Rolo Carlos Marques Palmeira Joan Roselló-Catafau 
Supported by Fondo de Investigaciones Sanitarias,No.FIS PI12/00519;Eirini Pantazi is the recipient of a fellowship from AGAUR,No.2012FI_B00382,Generalitat de Catalunya,Barcelona,Catalonia,Spain
AIM:To investigate the possible involvement of Sirtuin1(SIRT1)in rat orthotopic liver transplantation(OLT),when Institute Georges Lopez 1(IGL-1)preservation solution is enriched with trimetazidine(TMZ).METHODS:Male Sp...
关键词:SIRTUIN 1 ISCHEMIA-REPERFUSION INJURY LIVER transp 
Protein Globule Formation in the Liver Graft during Cold Preservation for Liver Transplantation: Its Clinical and Pathological Significance
《Open Journal of Pathology》2013年第3期119-126,共8页Changyin Feng Tongmei He Haijian Huang Lijuan Qu Yi Jiang Wenhua Zhang Zhiyong Zheng 
In liver transplantation, liver graft ischemia-reperfusion injury occurs mainly due to cold preservation and warm reperfusion. In this research, we study the affection of plasma protein of the donor on liver graft dur...
关键词:HEPATITIS B Virus IMMUNOHISTOCHEMISTRY LIVER Transplantation LIVER ISCHEMIA-REPERFUSION Injury 
Influence of Kupffer cells and platelets on ischemia-reperfusion injury in mild steatotic liver被引量:6
《World Journal of Gastroenterology》2013年第9期1396-1404,共9页Koichi Ogawa Tadashi Kondo Takafumi Tamura Hideki Matsumura Kiyoshi Fukunaga Tatsuya Oda Nobuhiro Ohkohchi 
Supported by The Ministry of Education, Culture, Sports, Science, and Technology of Japan, KAKENHI, No. 22591499
AIM: To investigate the effect of mild steatotic liver on ischemia-reperfusion injury by focusing on Kupffer cells (KCs) and platelets. METHODS: Wistar rats were divided into a normal liver group (N group) and a mild ...
关键词:Steatotic LIVER MILD steatotic LIVER KUPFFER cell PLATELET ISCHEMIA-REPERFUSION Intravital microscopy 
Current protective strategies in liver surgery被引量:7
《World Journal of Gastroenterology》2010年第48期6098-6103,共6页Kurinchi S Gurusamy Hector D Gonzalez Brian R Davidson 
During liver resection surgery for cancer or liver transplantation,the liver is subject to ischaemia (reduction in blood flow) followed by reperfusion (restoration of blood flow),which results in liver injury [ischemi...
关键词:LIVER HEPATECTOMY LIVER transplantation ISCHEMIA-REPERFUSION injury HYPOTHERMIA ISCHAEMIC PRECONDITIONING 
Changes of sphingolipids profiles after ischemia-reperfusion injury in the rat liver被引量:5
《Chinese Medical Journal》2009年第24期3025-3031,共7页ZHAI Shu-ting LIU Guang-yi XUE Fei SUN Gong-ping LIANG Liang CHEN Wei XU Guo-dong LI Jun-jian YANG Jun LIANG Ting-bo 
This work was supported partly by grants from the National Natural Science Foundation of China (No. 30772054 and No. 30672071).
Background Hepatic ischemia-reperfusion (I/R) injury occurs in many clinical procedures. The molecular mechanisms responsible for hepatic I/R injury however remain unknown. Sphingolipids, in particular ceramide, pla...
关键词:lipidomic SPHINGOLIPIDS LIVER ISCHEMIA-REPERFUSION matrix-assisted laser desorption ionizationtime-of-flight mass spectrometry 
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