supported by the JSPS KAKENHI Grant-in-Aid for Scientific Research(Grant number:21K19441,22H03183)(to MK);Early-Career Scientists(Grant number:21K15185)(to IN)and(Grant number:20K16485)(to MH).
Stroke is the second leading cause of death and the third leading cause of disability worldwide after heart disease.Researchers predict that stroke deaths and permanent disabilities will increase worldwide by the year...
Objective The present study aimed to investigate the effects of rTMS on astrocytic polarization during cerebral ischemic/reperfusion injury.Methods Three rTMS protocols were applied to primary astrocytes under normal ...
Objective This study aimed to evaluate the effect of different combinations of rTMS and cognitive training (rTMS-COG) on PSCI and identify the optimal combination protocol.Methods A cerebral infarction rat model was e...
[Objectives]To explore the role and molecular mechanisms of aerobic exercise in post-stroke depression.[Methods]Wistar rats were randomly divided into sham,sedentary and aerobic exercise(Ex)groups.The rats in sedentar...
Objective To clarify the effect of high-frequency repetitive transcranial magnetic stimulation (rTMS) on cognitive function in cerebral ischemic rats, and to explore its underlying mechanism by RNA sequencing.Methods ...
funded by Zhejiang Province Science and Technology Department Key R&D Program(2018C03084,2021C03097).
BACKGROUND: Anemia is prevalent in patients undergoing transcatheter aortic valve replacement(TAVR) and has been linked to impaired outcomes after the procedure. Few studies have evaluated the impact of anemia and new...
Supported by National Natural Science Foundation of China,No.81771154.
BACKGROUND Cerebral proliferative angiopathy(CPA)is a rare vascular disease characterized by the presence of diffuse vascular proliferation,progressive vascular hyperflow and vasodilation of multiple vessels in the no...
This study was supported by the Foundation of Hubei Provincal Department of Education of China(No.B2018098).
Acute focal cerebral ischemic stroke(IS)is a leading cause of morbidity and mortality worldwide.Acupuncture is an emerging alternative therapy that has been beneficial to acute brain ischemia.However,the underlying pr...
National Natural Science Foundation of China(81573406,81773703).
Cerebral ischemia remains the top causes of mortality and disability worldwide.The pathological mechanisms underlying ischemic brain injury are not fully illustrated.Cerebral ischemia induces massive mitochondrial dam...
National Natural Science Foundation of China(U1402221;81373997;81573640;81573636;81603315;81603316);Beijing Natural Science Foundation (7161011);CAMS Innovation Fundfor Medical Sciences (CIFMS) ( 2016-I2M-1-004);Key Research and Development Project of Hun
Ischemic stroke(IS) is a disease caused by deficiency of blood and oxygen in focal or complete brain,followed by inflammation cascade and other pathological reactions,which finally lead to irreversible damage to the c...