ITCH

作品数：93被引量：243H指数：8
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The Anterior Insula and its Projection to the Prelimbic Cortex are Involved in the Regulation of 5-HT-Induced Itch被引量：1
《Neuroscience Bulletin》2023年第12期1807-1822,共16页Juan Yao Xuan Li Guang-Yan Wu Bing Wu Jun-Hui Long Pu-Jun Wang Shu-Lei Liu Jie Gao Jian-Feng Sui 
supported by the National Natural Science Foundation of China(82271542);the Natural Science Foundation of Chongqing(cstc2020jcyj-msxm X0391 and cstc2019jcyj-msxm X0269);the Chongqing Medical Scientific Research Project(Joint project of Chongqing Health Commission and Science and Technology Bureau)(2023ZDXM001).
Itch is an unpleasant sensation that urges people and animals to scratch.Neuroimaging studies on itch have yielded extensive correlations with diverse cortical and subcortical regions,including the insular lobe.Howeve...
关键词：Itch-Insular cortex Prelimbic cortex Conditioned place aversion Pharmacogenetic inhibition 
An Anterior Cingulate Cortex-to-Midbrain Projection Controls Chronic Itch in
《Neuroscience Bulletin》2023年第5期793-807,共15页Ting-Ting Zhang Su-Shan Guo Hui-Ying Wang Qi Jing Xin Yi Zi-Han Hu Xin-Ren Yu Tian-Le Xu Ming-Gang Liu Xuan Zhao 
supported by grants from the National Natural Science Foundation of China(81873787,81961128024,32170994,and 82201362);Shanghai Natural Science Foundation(18ZR1424800 and 20ZR1430000);a Shanghai Municipal Science and Technology Major Project(2018SHZDZX05);the innovative research team of high-level local universities in Shanghai.
Itch is an unpleasant sensation that provokes the desire to scratch.While acute itch serves as a protec-tive system to warn the body of external irritating agents,chronic itch is a debilitating but poorly-treated clin...
关键词：sAnterior cingulate cortex Chronic itch Ventral tegmental area-Chemogenetics Neural circuit 
Third Special Issue on Mechanisms of Pain and Itch
《Neuroscience Bulletin》2022年第4期339-341,共3页Ru-Rong Ji 
supported by the National Natural Science Foundations of China(81620108008 and 31971112);the Innovation Capability Support Program of Shaanxi Province,China(2021TD-57).
We have published two special issues on pain and itch in Neuroscience Bulletin that cover their peripheral,central,and glial mechanisms[1,2],The first special was published in 2012[1],highlighting several topics such ...
关键词：SENSATION PAIN OPIOID 
Mitochondrial Reactive Oxygen Species Elicit Acute and Chronic Itch via Transient Receptor Potential Canonical 3 Activation in Mice被引量：1
《Neuroscience Bulletin》2022年第4期373-385,共13页Seong-Ah Kim Jun Ho Jang Wheedong Kim Pa Reum Lee Yong Ho Kim Hue Vang Kihwan Lee Seog Bae Oh 
supported by the National Research Foundation(NRF)funded by the Ministry of Science,ICT&Future Planning(NRF-2018R1A5A2024418 and NRF-2021R1A2C3003334);the Basic Science Research Program through the NRF funded by the Ministry of Education(NRF-2020R1I1A1A01068037).
Mitochondrial reactive oxygen species(mROS)that are overproduced by mitochondrial dysfunction are linked to pathological conditions including sensory abnormalities.Here,we explored whether mROS overproduction induces ...
关键词：MITOCHONDRIA Reactive oxygen species TRPC3 ITCH Dry skin Trigeminal ganglia 
Sympathetic Nerve Mediated Spinal Glia Activation Underlies Itch in a Cutaneous T-Cell Lymphoma Model被引量：3
《Neuroscience Bulletin》2022年第4期435-439,共5页Fang Tong Qianru He Wan-Jie Du Huan Yang Dongping Du Shaofeng Pu Qingjian Han 
supported by the National Natural Science Foundation of China(81971034);The Innovative Research Team of High-level Local Universities in Shanghai,Shanghai Pujiang Program(19PJ1401700);Building Project for Innovative team of National Traditional Chinese Medicine,and The Program for Professor of Special Appointment(Eastern Scholar)at Shanghai Institutions of Higher Learning,and the Priority Academic Program Development of Jiangsu High Education Institutions(PAPD).
Dear Editor,Cancer-associated itch can be described as pruritus associated with malignancy.Although intractable itch associated with specific types of cancer afflicts patients badly,few effective treatments are availa...
关键词：MALIGNANCY CANCER CANCER 
Descending Modulation of Spinal Itch Transmission by Primary Somatosensory Cortex被引量：3
《Neuroscience Bulletin》2021年第9期1345-1350,共6页Zi-Han Wu Han-Yu Shao Yuan-Yuan Fu Xiao-Bo Wu De-Li Cao Sheng-Xiang Yan Wei-Lin Sha Yong-Jing Gao Zhi-Jun Zhang 
This work was supported by grants from the National Natural Science Foundation of China(32030048,31970938,and 31871064);the Natural Science Foundation of Jiangsu Province(BK20191448).
Dear Editor,Itch(pruritus)is an unpleasant somatic sensation that is accompanied by the desire to scratch.While itch provides a warning signal that protects us from potential threats in normal conditions,severe or chr...
关键词：SENSATION ITCH SPINAL 
New Insight into the Origins of Itch and Pain:How are Itch and Pain Signals Coded and Discriminated by Primary Sensory Neurons?被引量：1
《Neuroscience Bulletin》2021年第4期575-578,共4页Yue Hu Wen-Qi Shan Bin Wu Tong Liu 
the National Natural Science Foundation of China(81870874);the Natural Science Foundation of Jiangsu Province,China(BK20170004);Jiangsu Key Laboratory of Neuropsychiatric Diseases(BM2013003)。
The unpleasant sensations itch and pain induce distinct behavioral patterns.Although both acute itch and pain serve protective functions,they are different sensory modalities.Itch stimuli lead to the scratching reflex...
关键词：removing protective SENSATION 
More than Scratching the Surface:Recent Progress in Brain Mechanisms Underlying Itch and Scratch被引量：2
《Neuroscience Bulletin》2020年第1期85-88,共4页Xu Liu Xiu-Hua Miao Tong Liu 
TL was supported by grants from the National Natural Science Foundation of China(81870874,31371179,81300968);the Natural Science Foundation of Jiangsu Province,China(BK20170004 and 2015-JY-029).XL was supported by the Postgraduate Research and Practice Innovation Program of Jiangsu Province,China(KYCX17_2034).
Itch(also called pruritus)is an unpleasant somatosensation that evokes a desire or reflex to scratch in humans and other mammals[1],Itch is now considered to be a unique sensory modality that is encoded by a labeled l...
关键词：SCRATCH eventually LYING 
Spinal Mechanisms of Itch Transmission被引量：6
《Neuroscience Bulletin》2018年第1期156-164,共9页Devin M.Barry Admire Munanairi Zhou-Feng Chen 
supported by NIH-NIDA T32 Training Grant 5T32DA007261-23;a W.M.Keck Fellowship;supported by NIH Grants 1ROIAR056318-06,R21NS088861-01A1,R01NS094344,R01 DA037261-01A1,and R56AR064294-01A1
Peripheral itch stimuli are transmitted by sensory neurons to the spinal cord dorsal horn, which then transmits the information to the brain. The molecular and cellular mechanisms within the dorsal horn for itch trans...
关键词：ITCH NEUROPEPTIDES Spinal cord DRG GPCR signaling 
Modulation of Pain and Itch by Spinal Glia被引量：14
《Neuroscience Bulletin》2018年第1期178-185,共8页Makoto Tsuda 
supported by JSPS KAKENHI Grant Numbers 15H02522;the Core Research for Evolutional Science and Technology(CREST)program;the Practical Research Project for Allergic Diseases and Immunology(Research on Allergic Diseases and Immunology)from Japan Agency for Medical Research and Development;the Toray Science Foundation;Takeda Science Foundation;The Nakatomi Foundation
Chronic pain and itch are a pathological operation of the somatosensory system at the levels of primary sensory neurons, spinal cord and brain. Pain and itch are clearly distinct sensations, and recent studies have re...
关键词：Neuropathic pain Chronic itch Microglia Astrocytes Spinal dorsal horn 
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