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作品数:2059被引量:2265H指数:16
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PathActMarker:an R package for inferring pathway activity of complex diseases
《Frontiers of Computer Science》2025年第3期123-124,共2页Xingyi LI Jun HAO Zhelin ZHAO Junming LI Xingyu LIAO Min LI Xuequn SHANG 
supported in part by the National Natural Science Foundation of China(Grant No.62202383);Guangdong Basic and Applied Basic Research Foundation(No.2024A1515012602);the National Key Research and Development Program of China(No.2022YFD1801200).
1 Introduction The process of complex diseases is closely linked to the disruption of key biological pathways,it is crucial to identify the dysfunctional pathways and quantify the degree of dysregulation at the indivi...
关键词:pathway activity DYSREGULATION complex diseases biological pathways disruption key biological pathwaysit identify dysfunctional pathways 
Key to Happiness
《China Today》2025年第4期70-72,共3页A.AFFES 
A Tunisian researcher finds the secret in a fusion of Arab culture,Chinese wisdom,and modern scientific thinking.WHEN I first arrived in China nearly 19 years ago,it wasn’t just about moving to a new country.It was t...
关键词:LIFE WISDOM CULTURE 
Key Mechanisms on Resource Optimization Allocation in Minority Game Based on Reinforcement Learning
《Tsinghua Science and Technology》2025年第2期721-731,共11页Changyan Di Tianyi Wang Qingguo Zhou Jinqiang Wang 
partially supported by the National Natural Science Foundation of China(Nos.U22A20261 and 61402210);the National Key R&D Program of China(No.2020YFC0832500);the Gansu Province Science and Technology Major Project-Industrial Project(No.22ZD6GA048);the Gansu Province Key Research and Development Plan-Industrial Project(No.22YF7GA004);the Fundamental Research Funds for the Central Universities(Nos.lzujbky-2022-kb12,lzujbky-2021-sp43,lzujbky-2020-sp02,lzujbky-2019-kb51,and lzujbky-2018-k12);the Science and Technology Plan of Qinghai Province(No.2020-GX-164);the Supercomputing Center of Lanzhou University,and the Gansu Provincial Science and Technology Major Special Innovation Consortium Project(No.21ZD3GA002)。
The emergence of coordinated and consistent macro behavior among self-interested individuals competing for limited resources represents a central inquiry in comprehending market mechanisms and collective behavior.Trad...
关键词:minority game optimization of resource allocation multi-agent system reinforcement learning 
LMSA:A Lightweight Multi-Key Secure Aggregation Framework for Privacy-Preserving Healthcare AIoT
《Computer Modeling in Engineering & Sciences》2025年第4期827-847,共21页Hyunwoo Park Jaedong Lee 
supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.NRF-2022R1C1C2012463).
Integrating Artificial Intelligence of Things(AIoT)in healthcare offers transformative potential for real-time diagnostics and collaborative learning but presents critical challenges,including privacy preservation,com...
关键词:Secure aggregation LIGHTWEIGHT federated learning 
Candidatus Liberibacter asiaticus influences the emergence of the Asian citrus psyllid Diaphorina citri by regulating key cuticular proteins
《Insect Science》2025年第2期501-514,共14页Chen-Yang Yuan Yi-Fan Gao Yi Liu Jia-Yao Fan Ying-Zhe Yuan Long Yi Tian-Xing Jing Wei Dou Jin-Jun Wang 
supported by the National Key R&D Program of China(2021YFD1400805);the National Natural Science Foundation of China(32160625);the Science and Technology Projects in Jiangxi Province(20225BCJ22005)and the China Agriculture Research System:CARS-26.
The Asian citrus psyllid,Diaphorina citri,is the primary vector of the HLB pathogen,Candidatus Liberibacter asiaticus(CLas).The acquisition of CLas shortens the developmental period of nymphs,accelerating the emergenc...
关键词:Candidatus Liberibacter asiaticus cuticular proteins Diaphorina citri EMERGENCE HUANGLONGBING 
Association analysis of an anti-obesity mechanism and key ripened Pu-erh tea bioactive components by mimicking human general tea drinking
《Food Science and Human Wellness》2025年第2期450-468,共19页Junyu Liu Zhengyang Song Haihong Chen Wen Zeng Guirong Han Wei Li Bing Xu Yuan Lu Canyang Zhang Zhenglian Xue Bin Lü Chong Zhang Song Yang Yi Wang Xinhui Xing 
The financial support received from the Shenzhen Science and Technology Innovation Commission(KCXFZ20201221173207022,WDZC20200821141349001);Shenzhen Bay Laboratory Startup Fund(21310041,S234602003)。
Pu-erh tea,a traditional Chinese beverage,performs an anti-obesity function,but the correlation between its components and efficacy remains unknown.Here,we screened two Pu-erh teas with significant anti-obesity effica...
关键词:ANTI-OBESITY Bioactive components Lipid metabolism Multiomics analysis Pu-erh tea 
Oral secretions:A key molecular interface of plant–insect herbivore interactions
《Journal of Integrative Agriculture》2025年第4期1342-1358,共17页Bin Li Wangpeng Shi Shaoqun Zhou Guirong Wang 
received financial support from the Shenzhen Science and Technology Program,China(KQTD20180411143628272);the special funds for Science Technology Innovation and Industrial Development of Shenzhen Dapeng New District,China(PT202101-02)。
The oral secretions of insect herbivores are complex mixtures of organic and inorganic solutes and enzymes that are deposited onto plant tissues during the feeding process.Some specific components of insect oral secre...
关键词:plant–insect interactions insect herbivores oral secretions plant defense 
颈椎后路脊柱内镜下Key-Hole技术治疗神经根型颈椎病
《颈腰痛杂志》2025年第2期280-285,共6页陈太声 刘雄 
广西中管局自筹经费课题(GXZYZ20210048)。
目的探讨运用颈后入脊柱微创内镜下Key-Hole技术治疗神经根型颈椎病(CSR)的治疗疗效。方法随机选取81例诊断CSR且进行手术治疗的患者,其中行颈椎前路椎间盘切除减压植骨融合术(ACDF)患者45例,Key-Hole患者36例,两组患者在病程、性别、...
关键词:神经根型颈椎病 脊柱内镜Key-Hole ACDF 脊柱微创 治疗疗效 治疗费用 
Evaluation of cropland suitability and key potential areas on the Qinghai-Tibet Plateau
《Journal of Geographical Sciences》2025年第4期800-820,共21页YANG Hua XU Yong LI Jiuyi ZHOU Kan 
The Second Tibetan Plateau Scientific Expedition and Research Program;No.2019QZKK0406。
Cropland suitability analysis is a vital tool for ensuring food security and sustainable agriculture,coordinating ecological space with human activity space on the Qinghai-Tibet Plateau(QTP).However,there are few stud...
关键词:land resources cropland suitability key potential areas potentially available cropland QinghaiTibet Plateau 
FAM20C:A key protein kinase in multiple diseases
《Genes & Diseases》2025年第2期255-270,共16页Rui Zhangg Yanming Ren Yan Ju Yuekang Zhang Yan Zhang Yuan Wang 
supported by the National Key Research and Development Program of China,Stem Cell and Translational Research (2022YFA1105200);the National Natural Science Foundation of China (82273117);Sichuan Science and Technology Program (23ZYZYTS0150);supported by the National Natural Science Foundation of China (82173179);the National Clinical Research Center for Geriatrics (Z2021JC006);supported by the National Natural Science Foundation of China (82302627);the Science and Technology Supportive Project of Sichuan Province (2022YFS0143);supported by the Science and Technology Supportive Project of Sichuan Province (2022YFS0049).
Family with sequence similarity 20 C(FAM20C)is a Golgi protein kinase that phos-phorylates the serine residue in the S-x-E/pS motif of target proteins.FAM2oC phosphorylates most secreted proteins,which play important ...
关键词:Biological functions BIOMINERALIZATION Cancer progression FAM20C Protein phosphorylation 
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