supported in part by the Siteman Cancer Center Precision Medicine Pathway(Grant No.T32CA113275);Erica C.Pehrsson is supported by a Postdoctoral Fellowship from the American Cancer Society(Grant No.PF-17-201-01);Erica C.Pehrsson,Jennifer A.Karlow,and Ting Wang are supported by the National Institutes of Health[Grant Nos.R01HG007354(National Human Genome Research Institute);R01HG007175(National Human Genome Research Institute);R01ES024992(National Institute of Environmental Health Sciences);U01CA200060(National Cancer Institute);U24ES026699(National Institute of Environmental Health Sciences);U01HG009391(National Human Genome Research Institute)];the American Cancer Society(Grant No.RSG-14-049-01-DMC).
Epigenetic alterations are widespread in cancer and can complement genetic alterations to influence cancer progression and treatment outcome.To determine the potential contribution of DNA methylation alterations to tu...