MACROCYCLIC

作品数:136被引量:115H指数:5
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相关领域:理学更多>>
相关作者:郭东升王爱琴章虹王颖刘育更多>>
相关机构:密歇根州立大学董事会苏州亚盛药业有限公司亚盛医药集团(香港)有限公司南开大学更多>>
相关期刊:《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Science China Chemistry》《Advances in Biological Chemistry》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划福建省自然科学基金国家教育部博士点基金更多>>
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Polyoxygenated cembrane-type diterpenes from the Hainan soft coral Lobophytum crassum as a promising source of anticancer agents with ErbB3 and ROR1 inhibitory potential
《Acta Pharmacologica Sinica》2025年第1期196-207,共12页Shou-mao Shen Dan-dan Yu Lin-mao Ke Li-gong Yao Ming-Zhi Su Yue-wei Guo 
This research was financially supported by the National Natural Science Foundation of China(Nos.22167010 and 81991521);the National Key Research and Development Program of China(No.2022YFC2804100);the Natural Science Foundation of the Higher Education Institutions of Jiangsu Province(No.23KJB350011);the Shandong Laboratory Program(SYS202205);the Basic Research Project of Guizhou University(No.2023-51).
A detailed chemical investigation of the Hainan soft coral Lobophytum crassum led to the identification of a class of polyoxygenated cembrane-type macrocyclic diterpenes(1-28),including three new flexible cembranoids,...
关键词:Lobophytum crassum macrocyclic diterpenes cembranoids anticancer agent ROR1 ERBB3 
Macrocyclic Calixpyridinium as a Photoacid for the Construction of Photoresponsive Supramolecular Materials
《Chinese Journal of Chemistry》2024年第24期3331-3336,共6页Kui Wang Si-Chen Liu Yu-Ting Wang Xin Meng Jian-Wen Wei Xin Yan 
We thank the Natural Science Foundation of Tianjin City(20JCYBJC00330)for financial support.
pH is an important stimuli-responsive signal because deprotonation-protonation process is crucial for many life functions.Photoacid is a kind of photoresponsive group that can release protons upon irradiation.This pro...
关键词:Macrocycles Host-guest systems SELF-ASSEMBLY PHOTORESPONSE Photoacid Supramolecular chemistry Weak intermolecular interactions AGGREGATION 
Asymmetric macrocyclization enabled by Rh(Ⅲ)-catalyzed C-H activation:Enantioenriched macrocyclic inhibitor of Zika virus infection
《Chinese Chemical Letters》2024年第11期378-383,共6页Chao Chen Wenwen Yu Guangen Huang Xuelian Ren Xiangli Chen Yixin Li Shenggui Liang Mengmeng Xu Mingyue Zheng Yaxi Yang He Huang Wei Tang Bing Zhou 
supported by National Natural Science Foundation of China(No.81973166);Science and Technology Commission of Shanghai Municipality(No.22XD1424600);Natural Science Foundation of Shanghai Municipality(No.22ZR1474100);Taishan Scholar Foundation of Shandong Province(No.tsqn202306322);National Key R&D Program of China(No.2021YFC2300700);Shandong Laboratory Program(No.SYS202205);Shandong Provincial Natural Science Foundation(Nos.ZR2023LSW003 and ZR2023JQ028)。
The development of enantioselective C-H macrocyclizations to efficiently access structurally diversified macrocycles is highly desirable,but remain a big challenge.Herein,we reported the first rhodium(Ⅲ)-catalyzed as...
关键词:C-H activation Carboamidation Enantioselective macrocyclization Anti-Zika virus activity 
Triplet−Triplet Annihilation-Based Photon Upconversion with a Macrocyclic Parallel Dimer
《Precision Chemistry》2024年第10期539-544,共6页Catherine H.Mulyadi Masanori Uji Bhavesh Parmar Kana Orihashi Nobuhiro Yanai 
supported by the JST START(JPMJSF2303);JSPS KAKENHI(JP23H00304,JP22KF0295,JP23KJ1717);Kyushu University Platform of Inter-/Transdisciplinary Energy Research(Q-PIT)through its“Module-Research Program”;Kyushu University Integrated Initiative for Designing Future Society.
The integration of multiple chromophore units into a single molecule is expected to improve the performance of photon upconversion based on triplet−triplet annihilation(TTA-UC)that can convert low energy photons to hi...
关键词:photon upconversion triplet−triplet annihilation macrocyclic parallel dimer spin statistical factor anthracene 
Macrocyclic trichothecenes from Myrothecium verrucaria PA 57 and their cytotoxic activity
《Chinese Journal of Natural Medicines》2024年第9期854-863,共10页MO Jisong TAN Yufen AI Wenjing LI Yunyun YUAN Yiyun JIANG Yueping XU Kangping TAN Guishan WANG Wenxuan LI Jing LIU Shao 
supported by the National Natural Science Foundation of China(No.82173713);the Natural Science Foundation of Hunan Province(Nos.2021JJ41000 and2021JJ40812);the Key Research and Development Program of Hunan Province(No.2022SK2031);the Project of Hunan Administration of Traditional Chinese Medicine(No.B2023059);the Postgraduate Scientific Research Innovation Project of Hunan Province(No.CX20230323)。
Four novel macrocyclic trichothecenes,termed mytoxins D-G(1-4),along with four known analogs(5-8),were isolated from the ethyl acetate extract of fermented rice inoculated with the fungus Myrothecium verrucaria PA57.E...
关键词:Macrocyclic trichothecenes Myrothecium verrucaria CYTOTOXICITY Secondary metabolite Soil fungi 
A novel fused bi-macrocyclic host for sensitive detection of Cr_(2)O_(7)^(2-)based on enrichment effect被引量:1
《Chinese Chemical Letters》2024年第7期291-295,共5页Ting-Ting Huang Jin-Fa Chen Juan Liu Tai-Bao Wei Hong Yao Bingbing Shi Qi Lin 
supported by the National Natural Science Foundation of China(NSFC,Nos.22065031,22061039,22001214,22165027);the top-notch talent project in Gansu province,the Key R&D Program of Gansu Province(No.21YF5GA066);Gansu Province College Industry Support Plan Project(No.2022CYZC-18);Natural Science Foundation of Gansu Province(Nos.2020–0405-JCC-630,20JR10RA088);The star of innovation(No.2023CXZX244)。
Improving the highly selective and sensitive binding of chemosensor to target guest is always very challenging.In order to solve this issue,herein,the enrichment effect was introduced into the design of chemosensor mo...
关键词:arene Bi-macrocyclic Detection of Cr_(2)O_(7)^(2−) DFT The enrichment effect 
Macrocyclic peptides:up-and-coming weapons to combat antimicrobial resistance
《Signal Transduction and Targeted Therapy》2024年第5期1786-1787,共2页Wen-Jing Wang Xiang-Min Dong Guo-Bo L 
The authors acknowledge that this work was partly supported by the National Natural Science Foundation of China(82122065 and 82073698 to G.B.L.);the Sichuan Science and Technology Program(2022YFH0027 to G.B.L.).
Recently,two companion papers published in Nature reported a first-in-class tethered macrocyclic peptide antibiotic targeting carbapenem-resistant A.baumannii(CRAB)and unveiled their unique antibacterial mechanism,whi...
关键词:outer MACROCYCLIC MACROCYCLIC 
Zwitterionic ring-opening polymerization of macrocyclic ethyleneoxy-substituted carbonate:Access to cyclic PEG-like polycarbonate
《Chinese Chemical Letters》2024年第3期282-286,共5页Jin Huang Jinwen Li Rui Yan Yuanyuan Qu Fengzhen Guo Lei Shen Can-liang Ma Jie Sun Zhenjiang Li Kai Guo 
the China Postdoc Council(OCPC)for the financial support of Postdoctoral International Exchange Program(No.YJ20210095);the financial support from the National Natural Science Foundation of China(No.22078150);National Key R&D Program of China(No.2021YFC2101904);the Jiangsu National Synergetic Innovation Center for Advanced Materials(SICAM);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD),the Jiangsu Synergetic Innovation Center for Advanced Bio-Manufacture(No.XTB2201);the Top-Notch Academic Programs Project of Jiangsu Higher Education Institutions(TAPP)。
The innovation in polymer design to rival conventional polyethylene glycol(PEG)is an important approach to achieving a more sustainable society.Here,cyclic PEG-like polycarbonates having high molecular weight(4.4–49....
关键词:Zwitterionic ring-opening polymerization Cyclic polycarbonate Macrocycles Tetrahedral intermediate NHC carbene 
Recent advances in long-persistent luminescence materials based on host–guest architecture
《Chinese Chemical Letters》2024年第1期84-94,共11页Tiantian Wang Man Liu Jiayi Mao Yimeng Liang Lichang Wang Dongzhi Liu Tianyang Wang Wenping Hu 
o National Natural Science Foundation of China(No.22178263);Natural Science Foundation of Tianjin City(No.22JCQNJC00770);Haihe Laboratory of Sustainable Chemical Transformations.The authors also thank Mr.Ben Parks from the Southern Illinois University Carbondale for proofreading the manuscript.
Organic long-persistent luminescence(LPL)materials,featuring low preparation cost,eco-friendly synthesis,and easy modification of functional groups,have exhibited extensive applications in information encryption,anti-...
关键词:Organic long-persistent luminescence Host-guest interaction Small molecule MACROCYCLIC Polymer 
The 10^(th)macrocylic arene supramolecular chemistry symposium
《Chinese Chemical Letters》2023年第12期1-3,共3页Shuquan Zhang Meijin Lin Andrew C.H.Sue Liping Cao Feng Wang Cheng Yang Tao Tu Feihe Huang Leyong Wang 
In the last few decades,there has been a rapid emergence and growing interest in synthetic macrocyclic arenes,such as calixarenes[1,2],cyclophanes[3],cyclotriveratrylenes[4],pillararenes[5-7],and other novel macrocycl...
关键词:CHEMISTRY MACROCYCLIC PROPERTY 
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