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MESYLATE: 作品数：47被引量：113H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：胡春张孟迪朱辉雄毛颖赵烨更多>>; 相关机构：沈阳药科大学药渡经纬信息科技(北京)有限公司上海医科大学附属华山医院东华大学更多>>; 相关期刊：《Open Journal of Gastroenterology》《Bioactive Materials》《China Medical Abstracts(Internal Medicine)》《Journal of Northeast Agricultural University(English Edition)》更多>>; 相关基金：国家自然科学基金更多>>

An Alternative Mechanism for the Instant Removal of Hypervascular Anaplastic Meningioma with Recovery of Mentality with NaCl + KCl: 《Case Reports in Clinical Medicine》2024年第7期213-218,共6页Chur Chin; Background: There is limited information regarding adjuvant treatment for malignant meningiomas. Although external whole-brain irradiation is recommended, the patient’s family in our case rejected this modality. Nota...; 关键词：Malignant Meningioma Colloid Gold Camostat Mesylate No Radiotherapy No Recurrence

Efficacy and safety of Nafamostat mesylate in patients with endstage renal failure被引量：2: 《World Journal of Clinical Cases》2024年第1期68-75,共8页Kun Liu Zhen-Hua Li; BACKGROUND Recent studies on dialysis anticoagulation therapy in patients with renal failure have shown that Nafamostat mesylate,a broad-spectrum potent serine protease inhibitor,has strong anticoagulation and anti-fi...; 关键词：End-stage renal failure Nafamostat mesylate EFFECTIVENESS Safety study Chronic kidney diseases

6-Gingerol, asarinin, and deoxyschizandrin improve bronchial epithelium functions in an interleukin-13einduced BEAS-2B cell model被引量：1: 《Journal of Traditional Chinese Medical Sciences》2023年第2期218-227,共10页Shuai Li Shuzhen Guo Dayu Lin Jiang Yu Jiayang Tang Xiaoxi lv Yuping Zhang Qingqing Wang; This study was supported by the National Natural Science Foundation of China(81403313);the Vertical Development Fund of Beijing University of Chinese Medicine(2019-ZXFZJJ-062).; Objective:To explore the effects of 6-gingerol,asarinin,and deoxyschizandrindthe main components of Zingiber officinale(Willd.)Rosc.(Gan Jiang),Asarum heterotropoides f.var.mandshuricum(Maxim.)(Xi Xin),and Schisandra ...; 关键词：INTERLEUKIN-13 Mitochondrial function Mitoquinone mesylate 6-GINGEROL Asarinin DEOXYSCHIZANDRIN

HDAC I/IIb selective inhibitor Purinostat Mesylate combined with GLS1 inhibition effectively eliminates CML stem cells被引量：1: 《Bioactive Materials》2023年第3期483-498,共16页Qiang Qiu Linyu yang Yunyu Feng Zejiang Zhu Ning Li Li Zheng Yuanyuan Sun Cong Pan Huandi Qiu Xue Cui Wei He Fang Wang Yuyao Yi Minghai Tang Zhuang Yang Yunfan Yang Zhihui Li Lijuan Chen Yiguo Hu; Fundamental Research Funds for the Central Universities(2021SCU12022 to L.Yang);the 1.3.5 Project for Disciplines of Excellence(to Z.Li and L.Chen);West China Hospital,Sichuan University,the National Natural Science Foundation of China(82104211 to L.Yang);National Natural Science Foundation of China(81541092 and 81770103 to Y.Hu).; Purinostat Mesylate(PM)is a novel highly selective and active HDAC I/IIb inhibitor,and the injectable formulation of PM(PMF)based on the compound prescription containing cyclodextrin completely can overcome PM’s poor...; 关键词：Chronic myelogenous leukemia Leukemia stem cell Selective HDAC I/IIb inhibitor GLS1 Mouse model

Evaluation of the Pharmacokinetics of Nafamostat Mesylate during Continuous Renal Replacement Therapy被引量：1: 《Open Journal of Emergency Medicine》2022年第4期157-167,共11页Koji Konishi Satoki Inoue Masahiko Kawaguchi; Continuous renal replacement therapy (CRRT) is the preferred dialysis modality in critical care settings for patients with hemodynamic instability. Nafamostat mesylate (NM) is an anticoagulant commonly used (mainly in...; 关键词：Nafamostat Mesylate Continuous Renal Replacement Therapy Liver Dysfunction

Belumosudil mesylate(Rezurock): 《中国药物化学杂志》2022年第5期420-420,共1页王存(编译) 张美慧(审校); Belumosudil mesylate是由美国Kadmon生物制药公司研发的一种具有口服活性的选择性Rho相关卷曲螺旋蛋白激酶2(ROCK2)抑制剂,于2021年7月16日获美国食品药品管理局(FDA)批准上市,是FDA批准的第一个也是唯一一个ROCK2小分子抑制剂,其商品...; 关键词：慢性移植物抗宿主病小分子抑制剂成人患者生物制药公司治疗失败

Separation, Identification, Isolation and Characterization of Degradation Product of Osimertinib Tablets by UPLC-QTOF-MS/MS and NMR: Evaluation of <i>In-Silico</i>Safety Assessment for Osimertinib (OSM) and Degradation Product (DP): 《Advances in Biological Chemistry》2021年第1期15-29,共15页Arun D. Bhutnar Seema R. Saple Vikas V. Vaidya; The present work encompasses identification and characterization of major degradation product (DP) of OSM observed in base hydrolytic stress study. The separation of DP was carried o...; 关键词：Osimertinib Mesylate (OSM) Base Degradation Semi-Preparative Isolation and Characterizations by HPLC UPLC-QTOF-MS/MS NMR Techniques

Nafamostat mesylate attenuates the pathophysiologic sequelae of neurovascular ischemia被引量：4: 《Neural Regeneration Research》2020年第12期2217-2234,共18页George Zaki Ghali Michael George Zaki Ghali; Nafamostat mesylate,an apparent soi-disant panacea of sorts,is widely used to anticoagulate patients undergoing hemodialysis or cardiopulmonary bypass,mitigate the inflammatory response in patients diagnosed with acut...; 关键词：apoptosis cerebrovascular EXCITOTOXICITY infarction ISCHEMIA nafamostat mesylate necrosis neuroprotection serine protesae subarachnoid hemorrhage

Nafamostat mesylate-induced hyperkalemia in critically ill patients with COVID-19: Four case reports被引量：2: 《World Journal of Clinical Cases》2020年第21期5320-5325,共6页Masaki Okajima Yoshinori Takahashi Takaaki Kaji Naohiko Ogawa Hideyuki Mouri; BACKGROUND Nafamostat mesylate(NM)may prove to be one of the key drugs effective against coronavirus disease 2019(COVID-19)because of its anti-viral properties and the potential to manage coagulopathy.However,NM tends...; 关键词：COVID-19 Nafamostat HYPERKALEMIA Disseminated intravascular coagulation Respiratory insufficiency Case report

Identification of impurities in nafamostat mesylate using HPLC-ITTOF/MS:A series of double-charged ions: 《Journal of Pharmaceutical Analysis》2020年第4期346-350,共5页Yuxin Zhang Lufan An Lin Zhang Rulin Wang Yuan Tian Zunjian Zhang; This work was financially supported by the National Major Science and Technology Projects of China(2017ZX09101001);the Double First-Class University Project(CPU2018GY33).; Nafamostat mesylate is a serine protease inhibitor used in the treatment of acute pancreatitis.The impurities in nafamostat mesylate,the active pharmaceutical ingredient(API),were profiled via high performance liquid ...; 关键词：Nafamostat mesylate IMPURITY Structure identification Double-charged ion

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