This work was funded by the Natural Science Foundation of the Zhejiang Province,Grant No.LY17H280006;the National Natural Science Foundation of China,Grant No.81803776.
Sphingosine kinase 1(SphK1)is an important synthetase during the synthesis of sphingosine-1-phosphate(S1P)from sphingosine(Sph).Previous studies demonstrated that arsenic trioxide(As_(2)O_(3))could reduce the level of...