Military Medical Advancement Program for Air Force Medical University(2020SWAQ04);Shaanxi Innovation Ability Support Plan(2023-CX-PT-33);Shaanxi Province Natural Science Basic Research Program(2024JC-ZDXM-60,2022JQ-820);New Clinical Technology of Xijing Hospital(2023XJSY27);National Natural Science Foundation of China(82201627)。
Objective To investigate the distribution of mitochondria-associated molecule mRNA in cerebellar Purkinje cells.Methods Transgenic technology was used to prepare Pcp2-tdTomato mouse labeled Purkinje cells.The mRNAs of...
BACKGROUND Gastric cancer(GC)has a high mortality rate worldwide.Despite significant progress in GC diagnosis and treatment,the prognosis for affected patients still remains unfavorable.AIM To identify important candi...
Supported by the Scientific Fund of Jiangsu Province (No.BY2015039-10);the Aquatic Three Project of Jiangsu Province (No.Y2017-37);the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD);the Top-notch Academic Programs Project of Jiangsu Higher Education Institutions (TAPP);the Jiangsu Funding Program for Excellent Postdoctoral Talent
Global warming threatens freshwater ecosystems and compromises fish survival.To elucidate the role of miRNAs in the livers of heat stressed largemouth bass,juvenile fish was subject to heat stress under 37°C.Both mRN...
supported by the grants from National Key R&D Program of China(2021YFC2300702 and 2021YFC2300200);the Hubei Provincial Natural Science Foundation of China(2021CFB364);the National Natural Science Foundation of China(82130064,81825015,U22A20337 and 32000119);the Key Biosafety Science and Technology Program of Hubei Jiangxia Laboratory(JXBS001).
Inclusion bodies(IBs)of respiratory syncytial virus(RSV)are formed by liquid-liquid phase separation(LLPS)and contain internal structures termed“IB-associated granules”(IBAGs),where anti-termination factor M2-1 and ...
supported by the 111 Project(Grant No.B17043);the 2115 Talent Development Program of China Agricultural University。
Thousands of long-distance mobile mRNAs were identified from different grafting systems,based on high-throughput sequencing technology.Moreover,the long-distance delivery of RNAs was proved to involve multiple mechani...
This work was financially supported grants from the National Natural Science Foundation of China(31972391,32172529);the China Agriculture Research System of MOF and MARA(CARS-27);the Special Funds for Major Scientific and Technological Innovation from Shaanxi Province(2020zdzx03-01-01).
Studies have shown that the m6A reader primarily affects genes expression by participating in the regulation of mRNA localization,splicing,degradation,translation,and other metabolic processes.Previously,we discovered...