MRNAS

作品数:141被引量:298H指数:8
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相关作者:武胜昔李云庆王亚云王文刘翔宇更多>>
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马BMSCs成软骨细胞诱导分化及其关键lncRNAs-mRNAs的筛选分析
《中国农业大学学报》2025年第2期94-106,共13页赵方歆 魏奥 凌宇 房君 朱纯霄 焦如月 赵赟瑶 韩静 吴凯峰 李雪琼 李涛 曹俊伟 周欢敏 张焱如 刘春霞 
内蒙古自治区自然科学基金项目(2020MS03045);国家自然科学基金项目(32260871)。
为进一步筛选BMSCs(Bone marrow mesenchymal stem cells,BMSCs)成软骨细胞诱导分化中关键lncRNAs、mRNAs,本研究以马BMSCs为研究对象,对向软骨细胞诱导不同分化阶段的细胞开展全转录组测序,筛选出在BMSCs成软骨细胞分化中具有重要功能...
关键词: BMSCS 诱导分化 软骨细胞 lncRNA 
Visualizing the distribution of mitochondrial molecular mRNAs of cerebellar Purkinje cells by RNAscope
《空军军医大学学报》2024年第12期1353-1369,共17页LIU Hui NI Ziwei LIU Yuxuan LI Shujiao WU Feifei WANG Lu YANG Yanling WANG Yayun 
Military Medical Advancement Program for Air Force Medical University(2020SWAQ04);Shaanxi Innovation Ability Support Plan(2023-CX-PT-33);Shaanxi Province Natural Science Basic Research Program(2024JC-ZDXM-60,2022JQ-820);New Clinical Technology of Xijing Hospital(2023XJSY27);National Natural Science Foundation of China(82201627)。
Objective To investigate the distribution of mitochondria-associated molecule mRNA in cerebellar Purkinje cells.Methods Transgenic technology was used to prepare Pcp2-tdTomato mouse labeled Purkinje cells.The mRNAs of...
关键词:mitochondrial dynamics proteins RNAscope Purkinje cell CEREBELLUM 
Identification of differentially expressed mRNAs as novel predictive biomarkers for gastric cancer diagnosis and prognosis
《World Journal of Gastrointestinal Oncology》2024年第5期1947-1964,共18页Jian-Wei Zhou Yi-Bing Zhang Zhi-Yang Huang Yu-Ping Yuan Jie Jin 
BACKGROUND Gastric cancer(GC)has a high mortality rate worldwide.Despite significant progress in GC diagnosis and treatment,the prognosis for affected patients still remains unfavorable.AIM To identify important candi...
关键词:Gastric cancer Differentially expressed genes BIOINFORMATICS Hub genes Prognosis 
Differential expression of miRNAs and mRNAs in the livers of largemouth bass Micropterus salmoides under heat stress
《Journal of Oceanology and Limnology》2024年第2期594-608,共15页Xuqian ZHAO Zijie LIN Caijuan LI Hao ZHU Lingling LI Wenjia MAO Qufei LING 
Supported by the Scientific Fund of Jiangsu Province (No.BY2015039-10);the Aquatic Three Project of Jiangsu Province (No.Y2017-37);the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD);the Top-notch Academic Programs Project of Jiangsu Higher Education Institutions (TAPP);the Jiangsu Funding Program for Excellent Postdoctoral Talent
Global warming threatens freshwater ecosystems and compromises fish survival.To elucidate the role of miRNAs in the livers of heat stressed largemouth bass,juvenile fish was subject to heat stress under 37°C.Both mRN...
关键词:heat stress largemouth bass miRNA-mRNA interaction 
PABP-driven secondary condensed phase within RSV inclusion bodies activates viral mRNAs for ribosomal recruitment
《Virologica Sinica》2024年第2期235-250,共16页Qiang Zhang Hanzhe Ye Cong Liu Haiwu Zhou Mingbin He Xiaodong Liang Yu Zhou Kun Wang Yali Qin Zhifei Li Mingzhou Chen 
supported by the grants from National Key R&D Program of China(2021YFC2300702 and 2021YFC2300200);the Hubei Provincial Natural Science Foundation of China(2021CFB364);the National Natural Science Foundation of China(82130064,81825015,U22A20337 and 32000119);the Key Biosafety Science and Technology Program of Hubei Jiangxia Laboratory(JXBS001).
Inclusion bodies(IBs)of respiratory syncytial virus(RSV)are formed by liquid-liquid phase separation(LLPS)and contain internal structures termed“IB-associated granules”(IBAGs),where anti-termination factor M2-1 and ...
关键词:Respiratory syncytial virus(RSV) Inclusion bodies(IBs) Biomolecular condensates Liquid-liquid phase separation(LLPS) Secondary condensed phase mRNA activation 
猴痘病毒mRNA疫苗的构建及免疫评价
《中国病原生物学杂志》2024年第3期257-262,共6页唐家凤 庄忻雨 姜人月 狄亚心 杨松惠 张桐 许智强 于潼 田明尧 金宁一 
国家重点研发计划项目(No.2023YFD1800404)。
目的设计猴痘病毒(MPXV)抗原,选择多种方案设计抗猴痘病毒mRNA候选疫苗,并完成其表达鉴定及小鼠体内的免疫效果评价。方法选取猴痘病毒M1R、A35R、A29L、H3L基因设计三组候选抗原基因(命名为:M1RA35R、A29L-H3L-A35R、A35R-Fc),并设置...
关键词:猴痘病毒 痘苗病毒 mRNA疫苗 EEV IMV LNP-mRNAs 
Characteristics of long-distance mobile mRNAs from shoot to root in grafted plant species
《Horticultural Plant Journal》2024年第1期25-37,共13页Mengmeng Fu Zhen Xu Huaying Ma Yifan Hao Ji Tian Yi Wang Xinzhong Zhang Xuefeng Xu Zhenhai Han Ting Wu 
supported by the 111 Project(Grant No.B17043);the 2115 Talent Development Program of China Agricultural University。
Thousands of long-distance mobile mRNAs were identified from different grafting systems,based on high-throughput sequencing technology.Moreover,the long-distance delivery of RNAs was proved to involve multiple mechani...
关键词:Grafting combination Long-distance mobile mRNA TLS RNA binding proteins 
The m6A reader MhYTP2 regulates the stability of its target mRNAs contributing to low nitrogen tolerance in apple (Malus domestica)
《Horticulture Research》2023年第6期287-298,共12页Tianli Guo Zehua Yang Ru Bao Xiaomin Fu Na Wang Changhai Liu Fengwang Ma 
This work was financially supported grants from the National Natural Science Foundation of China(31972391,32172529);the China Agriculture Research System of MOF and MARA(CARS-27);the Special Funds for Major Scientific and Technological Innovation from Shaanxi Province(2020zdzx03-01-01).
Studies have shown that the m6A reader primarily affects genes expression by participating in the regulation of mRNA localization,splicing,degradation,translation,and other metabolic processes.Previously,we discovered...
关键词:DIS translation EXPRESSING 
mRNAs/microRNAs调控网络探索石斛花型差异分子机理研究
《热带作物学报》2023年第11期2179-2187,共9页臧睿 陈宇 赵美 郝玉恒 敖叠 李凯莉 方诗迪 赵奇明 和凤美 
国家自然科学基金项目(No.32260419);研究生创新课题(No.2022ZKY463)。
目前兰科植物花型多样性形成分子机理仍不清楚,本研究对铁皮石斛、美花石斛花器官进行转录组和microRNA测序,通过cytoscape构建miRNA-mRNA网络和靶基因蛋白互作网络并进行差异比较,以期在分子水平上探究2种石斛花型差异分子机理。转录...
关键词:铁皮石斛 美花石斛 花型 转录组 small RNA 调控网络 
转录组测序技术在猪肉质性状研究中的进展
《今日畜牧兽医》2023年第10期71-73,共3页李龙娇 
重庆市教委科学技术研究项目(KJQN202203501);重庆三峡职业学院科研项目(cqsx202010)。
猪肉的品质是影响人类健康的重要因素,围绕猪肉质量这一方面,研究人员尝试使用多种方式探究导致其差异的原因。而众多方法中,转录组测序技术在研究基因的表达、功能、揭示基因对于生物表型的调控方面有巨大的潜力。本文就转录组测序技...
关键词:猪肉品质 转录组测序 MRNAS ncRNAs 
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