刘冉

作品数:3被引量:24H指数:3
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供职机构:苏州大学医学部更多>>
发文主题:大鼠脑LC3DEGENERATIONCATHEPSINBECLINL更多>>
发文领域:医药卫生更多>>
发文期刊:《Neuroscience Bulletin》《法医学杂志》更多>>
所获基金:国家自然科学基金中国博士后科学基金更多>>
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Regulation of axonal regeneration following the central nervous system injury in adult mammalian被引量:3
《Neuroscience Bulletin》2008年第6期395-400,共6页刘冉 陈溪萍 陶陆阳 
supported by the National Natural Science Foundation of China(No.30571909,No.30872666);the Youth Teacher Foundation of Jiangsu Pro-vince(No.BU134701);China,and the Medical Development Foundation of Soochow University(No.EE134615)
It has been well established that the recovery ability of central nervous system (CNS) is very poor in adult mammals. As a result, CNS trauma generally leads to severe and persistent functional deficits. Thus, the i...
关键词:central nervous system ADULT REGENERATION REGULATION brain injury 
Autophagy is activated and might protect neurons from degeneration after traumatic brain injury被引量:11
《Neuroscience Bulletin》2008年第3期143-149,共7页张延波 李生兴 陈溪萍 杨丽 张运阁 刘冉 陶陆阳 
This work was supported by the National Natural Science Foundation of China (No. 30571909); the Youth Teacher Foundation of Jiangsu Province (No. BU134701); Medical Development Foundation of Soochow University (No. EE 134615); We also thank Jin-Sheng YANG for his help in polishing the English language.
Objective To investigate changes of autophagy after traumatic brain injury (TBI) and its possible role. Methods Rat TBI model was established by controlled cortical injury system. Autophagic double membrane structur...
关键词:AUTOPHAGY apoptosis traumatic brain injury LC3 BECLINL NEURODEGENERATION 
大鼠脑外伤后溶酶体酶Cathepsin-B和D的表达被引量:10
《法医学杂志》2006年第6期404-406,410,F0002,共5页张延波 陈溪萍 陶陆阳 秦正红 李生兴 杨丽 杨菊 张运阁 刘冉 
国家自然科学基金资助项目(30571909);国家博士后基金资助项目(32134006)
目的研究大鼠脑外伤后溶酶体酶cathepsin-B和-D是否被激活及其不同时段表达变化,阐述其与凋亡执行因子caspase-3表达的关系,并探讨对脑外伤诊断及形成时间的意义。方法采用自由落体打击法建立脑外伤动物模型,并对模型及对照样本进行免...
关键词:脑外伤 溶酶体 cathepsin—B cathepsin—D caspase-3 
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