Front Cardiovascular diseases are a major cause of death throughout the world.Proprotein convertase substilisin/kexin type 9(PCSK9)modulators may attenuate PCSK9-induced low-density lipoprotein receptor(LDLR)degradati...
This work was supported in part by research grants from the Zhejiang Provincial Natural Science Foundation of China(Grant No.LQ19H120003);National Nature Science Foundation of China(Grant No.81900910).
The objective is to introduce the application of intraoperative optical coherence tomography(iOCT)in pars plana vitrectomy(PPV)for various vitreoretinal diseases,and to report the 4-year assessment of feasibility and ...
supported by the General Program of National Natural Science Foundation of China(Nos.81373662 and 81874475);the Capacity Building Project of Chinese and Western Medicine Clinical Collaboration on major difficult disease in 2019,the National Natural Science Foundation of China(Nos.82004383 and 81873314);and the Science and Technology Program of Guangzhou(No.202102010273).
To the Editor:Osteoarthritis(OA)is one of the most common age-related diseases and is characterized by synovial inflammation and progressive degradation of cartilage.It was reported that one-third of 65-year-olds and ...
grants from the"973"Program(№ 2006CB504100/2006CB500701);the"863"Program(№ 2006AA02Z173;CAS KSCX1-YW-R-62)
c-Jun N-terminal protein kinases (JNK), also known as stress-activated protein kinases, were originally identified by their ability to phosphorylate the N-terminal of the transcription factor c-Jun and by their acti...
Supported by Special Fund for China Agricultural Industry Research System(CARS-170303);Special Fund for Agricultural Industry Research System of Yunnan Province(YNGZTX-4-92)
The pests, diseases and weeds in sugarcane areas of Lincang Nanhua Sugar Industry Co.,Ltd. were investigated at seedling stage, growth stage and maturity stage of sugarcane from 2012 to 2016. The occurrence and damag...
supported by competitive grants from the Ministerio de Ciencia,lnnovacion y Universidades,through the Carlos Ⅲ Institute of Health-Fondo de Investigacidn Sanitaria(P119/00545)to P.M.;CIBER Cardiovascular(Fondo de Investigacion Sanitaria del Instituto de Salud Carlos Ⅲ and cofunding by Fondo Europeo de Desarrollo Regional FEDER)to P.M.;CAM(S2017/BMD-3671-INFLAMUNE-CM)from the Comunidad de Madrid to P.M.;supported by the Instituto de Salud Carlos Ⅲ(ISCⅢ),the Ministerio de Ciencia e Innovacibn and the Pro CNIC Foundation and is a Severo Ochoa Center of Excellence(SEV-2015-0505);supported by the Formaci6n de Profesorado Universitario(FPU 16/02780)program of the Spanish Ministry of Education,Culture and Sports.
In the last decade,approaches based on T cells and their immunomodulatory receptors have emerged as a solid improvement in treatments for various types of cancer.However,the roles of these molecules in the therapeutic...
Gestational diabetes mellitus(GDM)is a specific disease during pregnancy that is characterized by the onset of abnormal maternal glucose tolerance,1 which was first discovered by O’Sullivan and Mahan2 in 1964.Since t...