纳他霉素高产菌株发酵培养基优化  

Optimizing fermentation medium of high natamycin-producing strain

作　　者：魏宝东[1] 王晓晨[1] 林雨舒[1] 

机构地区：[1]沈阳农业大学食品学院,辽宁沈阳110161

出　　处：《中国酿造》2009年第6期95-98,共4页China Brewing

基　　金：辽宁省教育厅资助项目(2008662)

摘　　要：考察不同碳源、氮源及前体物质对菌株Streptomyce natalensis摇瓶发酵生产纳他霉素的影响。试验表明,纳他霉素摇瓶发酵培养基最佳碳源为葡萄糖、糊精,浓度分别为40g/L和32g/L;最佳氮源为酵母粉,浓度为4.5g/L;前体物质丙酸钠加入量为0.20%,最适加入时间为对数生长后期(48h)。： The effects of carbon source, nitrogen source and precursor on natamycin production of Streptomyce natalensis in shake flask fermentation were studied. The results showed that 40g/L glucose or 32g/L dextrin was the optimum carbon source, and 4.5g/L yeast extract was the optimal nitrogen source during shake flask fermentation. The optimal addition time of the precusor, sodium propionate, was the later phase of logarithmic growth （48h） at a concentration of 0.20%.

关 键 词：纳他霉素 发酵 碳源 氮源 前体物质 

分 类 号：TQ929[轻工技术与工程—发酵工程]