亚麻籽油抗动脉粥样硬化作用的研究进展  

Advance in anti-atherosclerotic effect of flaxseed oil

作　　者：田光晶 马丛丛[1] 陈萌[1] 许继取[1] 黄庆德[1] 邓乾春[1] 黄凤洪[1] 

机构地区：[1]中国农业科学院油料作物研究所油料脂质化学与营养湖北省重点实验室,武汉430062

出　　处：《中国油脂》2017年第10期87-92,共6页China Oils and Fats

基　　金：国家自然科学基金(NSFC-31271856);现代农业产业技术体系胡麻体系(CARS-17);中国农业科学院科技创新工程(CAAS-ASTIP-2013-OCRI)

摘　　要：研究表明ω-3脂肪酸能够降低心血管疾病的发生危险,其生物学和分子效应能够调节动脉粥样硬化的形成和发展,包括对炎症反应、血小板功能、血压、甘油三酯水平及动脉粥样斑块稳定性的调节作用。ω-3脂肪酸包括α-亚麻酸、二十碳五烯酸和二十二碳六烯酸。亚麻籽油含有丰富的多不饱和脂肪酸,是α-亚麻酸最丰富的来源之一。此外,有研究表明亚麻籽油可有效减缓动脉粥样硬化的发展。主要对亚麻籽油抗动脉粥样硬化作用的研究现状进行综述,以期为研究亚麻籽油对动脉粥样硬化的改善作用提供理论参考。Studies show that ω-3 fatty acids can reduce the risk of the occurence of cardiovascular disease,and its biologic and molecular effects can modulate the development and progression of atherosclerosis,which include its effects on inflammation,platelet function,blood pressure,triglyceride levels and the stability of atherosclerotic plaques. The ω-3 fatty acids include α-linolenic acid,eicosapentaenoic acid and docosahexaenoic acid. Flaxseed oil is rich in polyunsaturated fatty acids,and it is one of the most abundant sources of α-linolenic acid. Furthermore,study shows that flaxseed oil can effectively slow down the development of atherosclerosis. The advance in anti-atherosclerotic effect of flaxseed oil was summarized in order to provide theoretical reference for the study of improvement of flaxseed oil on atherosclerosis.

关 键 词：亚麻籽油 Α-亚麻酸 内皮功能 炎症因子 氧化应激 高血压 

分 类 号：R151[医药卫生—营养与食品卫生学] TS225.1[医药卫生—公共卫生与预防医学]