西番莲果皮中膳食纤维的降脂保肝及润肠通便功能  

Hypolipidemic, Hepatoprotective and Laxative Effects of Dietary Fiber from Passiflora edulis Fruit Peel

作　　者：程明明[1] 黄苇[1] CHENG Mingming;HUANG Wei(College of Food Science, South China Agricultural University, Guangzhou 510640, China)

机构地区：[1]华南农业大学食品学院,广东广州510640

出　　处：《食品科学》2017年第11期202-207,共6页Food Science

基　　金：公益性行业(农业)科研专项(201303077)

摘　　要：目的:本研究探讨西番莲果皮中湿法改性膳食纤维的降脂保肝及润肠通便功能。方法:利用高脂饲料构建高脂小鼠模型,以湿法改性膳食纤维灌胃给药6周,测定高、中、低不同给药剂量组的相关指标。结果:与模型对照组相比,阳性对照组、高剂量组和中剂量组小鼠血清总胆固醇水平、甘油三酯水平和丙二醛含量都有所下降,高密度脂蛋白胆固醇水平、谷丙转氨酶、谷草转氨酶、谷胱甘肽过氧化物歧化酶和超氧化物歧化酶活性都有所提升,高剂量组和中剂量组的低密度脂蛋白胆固醇水平下降,且都差异显著。结论:西番莲果皮膳食纤维具有较好的降血脂和保肝功能,并且功效和剂量呈现一定的依赖关系。各灌胃组的小鼠排便量差异不显著,但粪便含水率都显著增加,说明该改性纤维具有一定预防便秘的功效。Objective:To discuss the hypolipidemic,hepatoprotective and laxative effects of dietary fiber from Passifloraedulis fruit peel.Methods:An animal model of hyperlipidemia was established by feeding mice with a high-fat diet in thisstudy,and the mice were gavaged with the dietary fiber modified by the wet method at low,medium and high doses for sixweeks.Parameters of interest were measured in the blood and viscera of the mice were measured during the period.Results:The serum levels of total cholesterol(TC),triglyceride(TG),and malondialdehyde(MDA)activity in the positive controlgroup,high dose group,and middle dose group decreased compared with the model group.Moreover,the levels of alanineaminotransferase(ALT),aspertate aminotransferase(AST),high-density lipoprotein(HDL-C),glutathione peroxidase(GSH-Px),and superoxide dismutase(SOD)were improved to some extent.The levels of low-density lipoprotein(LDL-C)in thehigh dose group and middle dose group were significantly reduced in contrast to the model group.Conclusion:The dietaryfiber has good capacity to reduce blood fat and protect liver function in a dose-dependent manner.Although not significantdifferent from each other in terms of the stool quantity,the various dose groups presented a significant increase in the fecalmoisture content,indicating that the modified fiber to be effective in preventing constipation.

关 键 词：西番莲果皮 膳食纤维 降血脂 保肝 润肠通便 

分 类 号：TS201.1[轻工技术与工程—食品科学]