supported by grants from the National Natural Science Foundation of China (31771161, 81720108013, 81230025, 81200859 and 81801096);Key Project of Nature Science Foundation of Jiangsu Education Department (17KJA320005);Natural Science Foundation of Jiangsu Province (BK20171159);the Qing-Lan Project of Jiangsu, the Six Talent Summit Project of Jiangsu;the 333 High-level Personnel Training Project of Jiangsu;the Priority Academic Program Development of Jiangsu Higher Education Institutions, the Jiangsu Provincial Special Program of Medical Science (BL2014029);the Postgraduate Research & Practice Innovation Program of Jiangsu Province (KYCX19–2241 and KYCX20_2449), China。
Mesocorticolimbic dopaminergic(DA) neurons have been implicated in regulating nociception in chronic pain, yet the mechanisms are barely understood. Here, we found that chronic constructive injury(CCI) in mice increas...