NOCICEPTION

作品数：51被引量：106H指数：6
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相关领域：医药卫生更多>>
相关作者：魏滨陈军更多>>
相关机构：第四军医大学唐都医院东南大学北京大学第三医院更多>>
相关期刊：《口腔医学研究》《Chinese Medical Journal》《World Journal of Diabetes》《Neural Regeneration Research》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Bidirectional regulation of the brain-gut-microbiota axis following traumatic brain injury被引量：1
《Neural Regeneration Research》2025年第8期2153-2168,共16页Xinyu You Lin Niu Jiafeng Fu Shining Ge Jiangwei Shi Yanjun Zhang Pengwei Zhuang 
supported by the National Natural Science Foundation of China,No.82174112(to PZ);Science and Technology Project of Haihe Laboratory of Modern Chinese Medicine,No.22HHZYSS00015(to PZ);State-Sponsored Postdoctoral Researcher Program,No.GZC20231925(to LN)。
Traumatic brain injury is a prevalent disorder of the central nervous system.In addition to primary brain parenchymal damage,the enduring biological consequences of traumatic brain injury pose long-term risks for pati...
关键词：traumatic brain injury brain-gut-microbiome axis gut microbiota NEUROIMMUNE immunosuppression host defense vagal afferents bacterial infection dorsal root ganglia nociception neural circuitry 
Effect of quantitative consciousness index on seizure parameters during electroconvulsive therapy in patients with major depressive disorder被引量：1
《World Journal of Psychiatry》2024年第9期1375-1385,共11页Bang-Shu Zhao Bi Deng Qi-Bin Chen Xiao Li You Yang Su Min 
the National Natural Science Foundation of China,No.81873798 and No.81901377;Chongqing Science and Technology Bureau Under Grant,No.cstc2019jcyj-msxmX0839.
BACKGROUND Electroconvulsive therapy(ECT)is both an effective treatment for patients with major depressive disorder(MDD)and a noxious stimulus.Although some studies have explored the effect of sedation depth on seizur...
关键词：Electroconvulsive therapy PROPOFOL NOCICEPTION DEPRESSION ELECTROENCEPHALOGRAM 
Ventral Hippocampal CA1 Pyramidal Neurons Encode Nociceptive Information
《Neuroscience Bulletin》2024年第2期201-217,共17页Yue Wang Naizheng Liu Longyu Ma Lupeng Yue Shuang Cui Feng-Yu Liu Ming Yi You Wan 
supported by the National Natural Science Foundation of China(81974166,32271053,and 31872774).
As a main structure of the limbic system,the hippocampus plays a critical role in pain perception and chronicity.The ventral hippocampal CA1(vCA1)is closely associated with negative emotions such as anxiety,stress,and...
关键词：Ventral hippocampal CA1 NOCICEPTION Mechanical allodynia In vivo recording Neural coding 
A direct spino-cortical circuit bypassing the thalamus modulates nociception被引量：2
《Cell Research》2023年第10期775-789,共15页Bing Cai Dan Wu Hong Xie Yan Chen Huadong Wang Sen Jin Yuran Song Anan Li Shiqi Huang Sashuang Wang Yingjin Lu Lan Bao Fuqiang Xu Hui Gong Changlin Li Xu Zhang 
supported by the National Natural Science Foundation of China(32030050 and 32192413);Guangdong High Level Innovation Research Institute(2021B0909050004);CAMS Innovation Fund for Medical Sciences(2019-I2M-5-082),and Shenzhen Sanming Project.
Nociceptive signals are usually transmitted to layer 4 neurons in somatosensory cortex via the spinothalamic-thalamocortical pathway.The layer 5 corticospinal neurons in sensorimotor cortex are reported to receive the...
关键词：BYPASS CORTEX MORPHOLOGICAL 
Emerging roles of GPR109A in regulation of neuroinflammation in neurological diseases and pain被引量：6
《Neural Regeneration Research》2023年第4期763-768,共6页Kyle Taing Lawrence Chen Han-Rong Weng 
supported by the NIH RO1 grant(NS107569)to HRW。
Neuroinflammation plays a critical role in the pathological process of multiple neurological disorders and pathological pain conditions.GPR109A,a Gi protein-coupled receptor,has emerged as an important therapeutic tar...
关键词：β-hydroxybutyrate cytokines HCAR2 LUPUS NEUROINFLAMMATION NEUROPATHIC NIACIN NOCICEPTION synaptic 
The Differing Effects of Nociception and Pain Memory on Pain Thresholds in Participants with and without a History of Injury: A Pretest-Posttest Quasi Experimental Study
《Journal of Behavioral and Brain Science》2022年第8期359-379,共21页Derrick G. Sueki Kim Dunleavy Emilio J. Puentedura Lindsey Heard Peter Van der Heide Ming-Shun Cheng 
Purpose: Memory has been identified as an important protective feature to prevent future injury, but its role has yet to be ascertained. The current study aimed to determine whether there was a difference in pressure ...
关键词：Pain Memory NOCICEPTION Pressure Pain Threshold Pain Perception Pain Learning 
KCNQ Channels in the Mesolimbic Reward Circuit Regulate Nociception in Chronic Pain in Mice被引量：7
《Neuroscience Bulletin》2021年第5期597-610,共14页Hao-Ran Wang Su-Wan Hu Song Zhang Yu Song Xiao-Yi Wang Lei Wang Yang-Yang Li Yu-Mei Yu He Liu Di Liu Hai-Lei Ding Jun-Li Cao 
supported by grants from the National Natural Science Foundation of China (31771161, 81720108013, 81230025, 81200859 and 81801096);Key Project of Nature Science Foundation of Jiangsu Education Department (17KJA320005);Natural Science Foundation of Jiangsu Province (BK20171159);the Qing-Lan Project of Jiangsu, the Six Talent Summit Project of Jiangsu;the 333 High-level Personnel Training Project of Jiangsu;the Priority Academic Program Development of Jiangsu Higher Education Institutions, the Jiangsu Provincial Special Program of Medical Science (BL2014029);the Postgraduate Research & Practice Innovation Program of Jiangsu Province (KYCX19–2241 and KYCX20_2449), China。
Mesocorticolimbic dopaminergic(DA) neurons have been implicated in regulating nociception in chronic pain, yet the mechanisms are barely understood. Here, we found that chronic constructive injury(CCI) in mice increas...
关键词：NOCICEPTION Mesocorticolimbic system Ventral tegmental area Brain-derived neurotrophic factor KCNQ RETIGABINE Chronic neuropathic pain 
Evidence and explanation for the involvement of the nucleus accumbens in pain processing被引量：5
《Neural Regeneration Research》2020年第4期597-605,共9页Haley N.Harris Yuan B.Peng 
The nucleus accumbens(NAc)is a subcortical brain structure known primarily for its roles in pleasure,reward,and addiction.Despite less focus on the NAc in pain research,it also plays a large role in the mediation of p...
关键词：ANALGESIA CIRCUITRY deep brain stimulation NOCICEPTION nucleus ACCUMBENS PAIN PAIN relief PAIN signaling reward STRIATUM 
Lifting the veil on the keratinocyte contribution to cutaneous nociception
《Protein & Cell》2020年第4期239-250,共12页Matthieu Talagas Nicolas Lebonvallet Francois Berthod Laurent Misery 
Cutaneous nociception is essential to prevent individuals from sustaining injuries.According to the conventional point of view,the responses to noxious stimuli are thought to be exclusively initiated by sensory neuron...
关键词：KERATINOCYTE NOCICEPTION skin TRP PAIN inflammation 
Gene expression changes in dorsal root ganglia following peripheral nerve injury: roles in inflammation,cell death and nociception被引量：5
《Neural Regeneration Research》2019年第6期939-947,共9页Sarah L.Martin Adam J.Reid Alexei Verkhratsky Valerio Magnaghi Alessandro Faroni 
supported by the Hargreaves and Ball Trust,the National Institute for Health Research(II-LA-0313-20003)(to AJR);the Rosetrees Trust,the Academy of Medical Sciences,and the Manchester Regenerative Medicine Network(MaRMN)(to AF and AJR);Progetto Eccellenza from the Italian Ministry of Research(to VM)
Subsequent to a peripheral nerve injury, there are changes in gene expression within the dorsal root ganglia in response to the damage. This review selects factors which are well-known to be vital for inflammation, ce...
关键词：Gene expression polymerase chain reaction dorsal root GANGLIA INFLAMMATION NOCICEPTION cell death peripheral NERVE injury Schwann CELLS satellite GLIAL CELLS NERVE regeneration 
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