This work was supported by National Natural Science Foundation of China (No 81000435 and 81271129).Ming-wen FAN and Qing-an XU designed the study and revised the manuscript; Ling-kai SU, Fei YU, Zhao-fei LI, and Chang ZENG performed the experiments; and Ling-kai SU wrote the manuscript.
Aim: To investigate the effects of co-delivering 11_-6 expressing plasmid pCI-IL-6 on the immunogenicity of the anti-caries DNA vaccine pClA-P, which encodes the surface protein antigen PAc of Streptococcus mutans. M...