supported by the National Basic Research Program of China(2013CB911204);the National Key Scientific Instrument Development Program of China(2011YQ09000504);the National Natural Science Foundation of China(21275005,21235001)
Highly efficient and rapid proteolytic digestion of proteins into peptides is a crucial step in shotgun-based proteome-analysis strategy. Tandem digestion by two or more proteases is demonstrated to be helpful for inc...
supported by the National Key Basic Research Programs of China(Nos.2012CB910300, 2012CB721102,2013CB911204,and 2013CB945400);the National Natural Foundation of China(No.31030042);the Shanghai Basic Research Fund(Nos.11JC1401100 and 13XD 1400500).
Mounting evidence suggests that cellular metabolites, in addition to being sources of fuel and macromolecular substrates, are actively involved in signaling and epigenetic regulation. Many metabolites, such as cyclic ...