国家重点基础研究发展计划(2007CB512607)

作品数:22被引量:189H指数:9
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相关作者:肖小河赵艳玲王伽伯张琳李丰衣更多>>
相关机构:解放军第302医院成都中医药大学解放军第三○二医院湖南中医药大学更多>>
相关期刊:《Chinese Herbal Medicines》《Chinese Journal of Integrative Medicine》《中草药》《中国实验方剂学杂志》更多>>
相关主题:黄连中药药性微量热法循证医学慢性乙型肝炎更多>>
相关领域:医药卫生农业科学更多>>
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基于生物热动力学的黄连不同提取部分抑菌活性分析被引量:11
《中国实验方剂学杂志》2017年第16期51-56,共6页杨宏博 苏敏 刘慧浪 王京昆 赵艳玲 
国家重点基础研究发展计划(973计划)项目(2007CB512607);国家自然科学基金项目(30772740)
目的:从生物热力学角度,探讨黄连不同提取部分抑菌作用差异,为黄连活性成分的研究提供新思路和理论依据。方法:采用微量量热法,在LB培养基,37℃条件下,接种量为1×10~5个/mL无菌条件下,建立大肠埃希菌、金黄色葡萄球菌和志贺氏痢疾杆菌...
关键词:生物热动力学 微量量热法 黄连 水提物 生物碱部分 非生物碱部分 
Short-Term Efficacy of Treating Hepatitis B Virus-Related Acute-on-Chronic Liver Failure Based on Cold Pattern Differentiation with Hot Herbs: A Randomized Controlled Trial被引量:5
《Chinese Journal of Integrative Medicine》2016年第8期573-580,共8页郭玉明 李丰衣 宫嫚 张琳 王伽伯 肖小河 李筠 赵艳玲 王立福 张晓锋 
Supported by the Ministry of Science and Technology of China,through its National Key Projects for Basic Research(No.2007CB512607);National Eleventh Five-year Great Science and Technology Project(No.2008ZX10005-007)
Objective: To evaluate the clinical efficacy and safety of Yinchen Zhufu Decoction(茵陈术附汤, YCZFD) in the treatment of acute-on-chronic liver failure caused by hepatitis B virus(HBV-ACLF) with cold pattern in ...
关键词:hepatitis B virus-related acute-on-chronic liver failure mortality Chinese medicine cold pattern Yinchen Zhufu Decoction 
Study on Hot Property of Aconiti Lateralis Radix Praeparata and Its Compatibility with Zingiberis Rhizoma Based on Animal Temperature Tropism
《Chinese Herbal Medicines》2012年第4期294-300,共7页SUN Zhi-yong ZHAO Yan-ling WANG Jia-bo LI Rui-sheng WEI Si-si JIANG Feng-juan XIAO Xiao-he 
National Natural Sciences Foundation (81173571);National Basic Research Program of China (2007CB512607);The Major Projects of the National Science and Technology (2012ZX10005010-002-002)
Objective To establish an objective method for evaluating the intrinsic characteristics between hot and cold properties of herbal drugs and to study the hot property of Aconiti Lateralis Radix Praeparata(ALRP) and its...
关键词:Aconiti Lateralis Radix Praeparata animal temperature tropism clustering analysis compatibility Zingiberis Rhizoma 
Hot Property of Aconiti Lateralis Radix Praeparata and its Compatibility with Zingiberis Rhizoma Based on Animal Temperature Tropism
《Chinese Herbal Medicines》2012年第4期-,共7页SUN Zhi-yong1 
Abstract: Objective To establish an objective method for evaluating the intrinsic characteristics between hot and cold properties of herbal drugs and to study the hot property of Aconiti Lateralis Radix Praeparata (...
关键词:KEY words: Aconiti Lateralis RADIX Praeparata ANIMAL TEMPERATURE TROPISM clustering analysis compatibility Zingiberis Rhizoma 
基于慢性乙型肝炎的中药寒热药性研究
《中华中医药杂志》2012年第6期1515-1518,共4页张琳 李丰衣 王伽伯 赵艳玲 肖小河 李筠 
国家重点基础研究发展计划(973计划)(No.2007CB512607);"十一五"国家科技重大专项课题(No.2008ZX10005-007)~~
目的:探讨中药寒热药性对慢性乙型肝炎(CHB)患者肝功能的影响差异。方法:对本院采用中药治疗的253例CHB住院病历进行回顾性分析,通过构建CHB肝功能指标的因子结构模型,探索影响CHB疾病进展的关键因素;通过分析寒热方药对以上关键因素指...
关键词:寒热药性 循证医学 慢性乙型肝炎 因子分析 
Research on Fuzi based on animal thermotropism behavior to discover if it has fewer "hot" characteristics without Ganjiang被引量:4
《Journal of Traditional Chinese Medicine》2012年第2期208-214,共7页孙志勇 赵艳玲 王伽伯 张琳 魏思思 江凤娟 贾雷 程丹红 肖小河 
Supported by National Natural Sciences Foundation(No. 81173571);National Basic Research Program of China (No.2007CB512607)
OBJECTIVE:To investigate whether Fuzi(Radix Aconiti Praeparata) has fewer "hot" characteristics when administered without Ganjiang(Rhizoma Zingiberis).METHODS:Differences in the thermotropism behaviors of mice treated...
关键词:Animal thermotropic behavior Objectivity Cold/Hot tropism Fuzi(Radix Aconiti Praeparata) Ganjiang(Rhizoma Zingiberis) 
中药寒热药性循证医学数据库的建立及应用被引量:6
《世界中西医结合杂志》2012年第3期215-218,共4页张琳 李筠 庄永龙 李丰衣 
国家重点基础研究发展计划(973计划)课题(No.2007CB512607);国家十一五科技重大专项课题(No.2008ZX10005-007)
目的建立基于慢性乙型肝炎(CHB)的中药寒热药性循证医学数据库,为揭示中药寒热药性的科学内涵,探讨其临床指导意义提供科学支持。方法依据回顾性病例调查方法,制定一套规范化的中药寒热药性临床信息采集表,建立基于Java 2平台企业版(J2...
关键词:慢性乙型肝炎 循证医学 中药寒热药性 数据库 信息化管理 
"Dose-effect-response" Relationships of Paeoniae Radix Rubra on α-Naphthylisothiocyanate-induced Acute Cholestatic Hepatitis in Rats被引量:1
《Chinese Herbal Medicines》2011年第4期296-303,共8页WEI Si-si ZHAO Yan-ling JIANG Feng-juan JIA Lei ZHU Yun WANG Jia-bo SUN Zhi-yong LI Rui-sheng XIAO Xiao-he 
National Basic Research Program of China(2007CB512607)
Objective To investigate the hepatoprotective effects of Paeoniae Radix Rubra(PRR)at different doses against α-naphthylisothiocyanate(α-NIT)-induced acute cholestatic hepatitis in rats.Methods Rats were ig admini-st...
关键词:acute cholestatic hepatitis α-naphthylisothiocyanate cluster analysis correspondence analysis 'dose-effect-response'relationships Paeoniae Radix Rubra 
Study on the Complex Prescription Compatibility Law of the Cold and Hot Nature of Mahuang Decoction(麻黄汤) and Its Categorized Formulae Based on the Cold-Hot Pad Differentiating Assay被引量:1
《Chinese Journal of Integrative Medicine》2011年第4期290-295,共6页贾雷 赵艳玲 王伽伯 邹文俊 李瑞生 杨宏博 程丹红 肖小河 
Supported by the Major State Basic Research Development Program of China(973 Program,No.2007CB512607);the National Science Fund for Distinguished Young Scholars (No.30625042);National Science and Technology Major Project of the Ministry of Science and Technology of China(No. 2009ZX10005-017)
Objective:To explore the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction(麻黄汤,MHD) and Maxing Shigan Decoction(麻杏石甘汤,MXSGD),both categorized formulas but with differe...
关键词:Mahuang Decoction and its categorized formulae cold and hot nature of Chinese drugs complex prescription compatibility law of Chinese medicine cold-hot pad differentiating assay 
微量量热法研究左金丸与反左金丸对肠道菌群生长代谢的影响被引量:3
《中国中西医结合杂志》2011年第2期209-212,共4页程丹红 赵艳玲 杨宏博 王伽伯 贾雷 肖小河 
国家重点基础研究发展计划资助项目(973计划)(No.2007CB512607);国家自然科学基金资助项目(No.30772740)
目的从生物热动力学角度研究左金丸、反左金丸对肠道菌群生长代谢的影响,验证其客观差异性,探讨类方研究的新方法。方法采用微量量热法测定小鼠肠道菌群在不同浓度的左金丸、反左金丸作用下的生长代谢热谱曲线,以特征参数生长速率常数(k...
关键词:微量量热法 左金丸 反左金丸 肠道菌群 
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