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国家自然科学基金(U1132607): 作品数：23被引量：29H指数：3; 导出分析报告; 相关作者：刘吉开冯涛李正辉尹霞李学梅更多>>; 相关机构：中国科学院中国科学院大学云南农业大学鞍山师范学院更多>>; 相关期刊：《Chinese Journal of Natural Medicines》《药学学报》《天然产物研究与开发》《Natural Products and Bioprospecting》更多>>; 相关主题：CULTURESBASIDIOMYCETENEWNGCYTOTOXICITY更多>>; 相关领域：理学医药卫生经济管理更多>>

The Use of a Combination of RDC and Chiroptical Spectroscopy for Determination of the Absolute Configuration of Fusariumin A from the Fungus Fusarium sp.: 《Natural Products and Bioprospecting》2016年第1期41-48,共8页Liang-Yan Liu Han Sun Christian Griesinger Ji-Kai Liu; Support by the National Natural Science Foundation of China(U1132607)to J.K.L.;the DFG(Forschergruppe FOR 934)to C.G;as well as the Chinese/German foundation(GZ1104)to H.S.and C.G.is acknowledged.; A new alkylpyrrole derivative,fusariumin A(1),was isolated from the culture broth of the fungus Fusarium sp.The absolute configuration of fuasiumin A has been established as(2'R,3'R)using a combination of RDC(residual...; 关键词：NMR Residual dipolar coupling Relative configuration Absolute configuration Chiroptics

Three New Triterpenoids from European Mushroom Tricholoma terreum被引量：2: 《Natural Products and Bioprospecting》2015年第4期205-208,共4页Tao Feng Juan He Hong-Lian Ai Rong Huang Zheng-Hui Li Ji-Kai Liu; the National Natural Sciences Foundation of China(U1132607,81102346).; Three rare triterpenoids,saponaceolides Q–S(1–3),have been isolated from fruiting bodies of the mushroom Tricholoma terreum.Their structures were characterized based on extensive spectroscopic data.Compound 1 showed...; 关键词：Tricholoma terreum TRITERPENOIDS CYTOTOXICITY

白黄小脆柄菇发酵液中的一个新的血苋烷型倍半萜（英文）被引量：3: 《天然产物研究与开发》2015年第7期1131-1133,共3页李学梅尹霞李正辉冯涛刘吉开; Foundation Item:National Natural Science Foundation of China(U1132607,81102346); 从白黄小脆柄菇(Psathyrellacandolleana)发酵液提取物的乙酸乙酯层中分离得到一个新的血苋烷型倍半萜(1)和一个已知的没药烷型倍半萜(2)。通过质谱、核磁等方法确定化合物1的结构为15-hydroxy-drimenol。通过文献对照核磁数据确定化合...; 关键词：白黄小脆柄菇倍半萜结构鉴定

Structure-Based Optimization and Biological Evaluation of Pancreatic Lipase Inhibitors as Novel Potential Antiobesity Agents被引量：1: 《Natural Products and Bioprospecting》2015年第3期129-157,共29页Kun Wei Gang-Qiang Wang Xue Bai Yan-Fen Niu He-Ping Chen Chun-Nan Wen Zheng-Hui Li Ze-Jun Dong Zhi-Li Zuo Wen-Yong Xiong Ji-Kai Liu; The authors are grateful to the National Natural Science Foundation of China(81102348,U1132607,81373289).; The unusual fused b-lactone vibralactone was isolated from cultures of the basidiomycete Boreostereum vibrans and has been shown to significantly inhibit pancreatic lipase.In this study,a structure-based lead optimiza...; 关键词：Natural products Structure optimization Antiobesity agents Pancreatic lipase inhibitors Vibralactone derivatives

Steroids and Sesquiterpenes From Cultures of the Fungus Phellinus igniarius被引量：2: 《Natural Products and Bioprospecting》2015年第1期17-22,共6页Rong-Hua Yin Zhen-Zhu Zhao Xu Ji Ze-Jun Dong Zheng-Hui Li Tao Feng Ji-Kai Liu; the National Natural Sciences Foundation of China(U1132607,81102346);Natural Sciences Foundation of Yunnan Province(2011FB099).; Two new steroids,3a,17a,19,20-tetrahydroxy-4a-methylpregn-8-ene(1)and 3a,12a,17a,20-tetrahydroxy-4amethylpregn-8-ene(2)and three new sesquiterpenoids,12-hydroxy-a-cadinol(3),3a,12-dihydroxy-d-cadinol(4),and 3a,6a-dih...; 关键词：Pregnene steroids SESQUITERPENES Phellinus igniarius CYTOTOXICITY Vascular-activities

Four New Sesquiterpenoids from Cultures of the Fungus Phellinidium sulphurascens被引量：1: 《Natural Products and Bioprospecting》2015年第1期23-28,共6页Zhen-Zhu Zhao He-Ping Chen Tao Feng Zheng-Hui Li Ze-Jun Dong Ji-Kai Liu; National Natural Science Foundation of China(U1132607,81102346);Natural Science Fund of Yunnan province(2011FB099).; Four new sesquiterpenoids,namely 12-hydroxy-3-oxodrimenol(1),11-hydroxyacetoxydrim-7-en-3b-ol(2),2,6-dimethyl-7,10-epoxy-10-hydroxymethyldodeca-2,11-dien-6-ol(3),and 7,10-epoxy-2,6,10-trimethyldodeca-2,11-diene-4,6-di...; 关键词：Phellinidium sulphurascens Drimane 7 10-Epoxy-2 6 10-trimethyldodeca-2 11-diene

担子菌薄皮干酪菌中两个新的倍半萜(英文)被引量：3: 《药学学报》2014年第11期1578-1581,共4页郭华冯涛李正辉刘吉开; supported by the National Natural Science Foundation of China(U1132607,81102346);Youth Innovation Promotion Association of CAS(2011312D11019); 采用硅胶、RP-18、Sephadex LH-20等多种材料进行分离纯化,通过理化方法和波谱分析进行结构鉴定,从担子菌薄皮干酪菌(Tyromyces chioneus)发酵液的乙酸乙酯提取部位分离并鉴定了4个化合物,它们分别为:tyromol A(1)、tyromol B(2)、15-hy...; 关键词：薄皮干酪菌倍半萜 tyromolA tyromolB

Mycophenolic acid derivatives from cultures of the mushroom Laetiporus sulphureu被引量：1: 《Chinese Journal of Natural Medicines》2014年第9期685-688,共4页FAN Qiong-Ying YIN Xia LI Zheng-Hui LI Yan LIU Ji-Kai FENG Tao ZHAO Bao-Hua; supported by the National Basic Research Program of China(973 Program,No.2009CB 522300);the National Natural Sciences Foundation of China(Nos.30830113,U1132607); AIM: To investigate the chemical constituents of the cultures of Laetiporus sulphureus(Bull.) Murrill. METHOD: Compounds were isolated and purified by various chromatographic techniques. The structure of the new compo...; 关键词：Laetiporus sulphureus Mycophenolic acid derivatives CYTOTOXICITY

Three New Humulane Sesquiterpenes from Cultures of the Fungus Antrodiella albocinnamomea被引量：3: 《Natural Products and Bioprospecting》2014年第4期207-211,共5页Zi-Ming Chen Qiong-Ying Fan Xia Yin Xiao-Yan Yang Zheng-Hui Li Tao Feng Ji-Kai Liu; National Natural Science Foundation of China(U1132607,81373289,81102346);Youth Innovation Promotion Association of CAS(2011312D11019).; Three new humulane-type sesquiterpenes,antrodols A–C(1–3),were isolated from cultures of the fungus Antrodiella albocinnamomea.Their structures were elucidated on the basis of extensive spectroscopic analysis.Antrod...; 关键词：Antrodiella albocinnamomea Humulane-type sesquiterpenes Protein tyrosine phosphatase inhibitory activity

Five New Guanacastane-Type Diterpenes from Cultures of the Fungus Psathyrella candolleana: 《Natural Products and Bioprospecting》2014年第3期149-155,共7页Xia Yin Tao Feng Zheng-Hui Li Ying Leng Ji-Kai Liu; the National Natural Sciences Foundation of China(U1132607,81373289).; Five new guanacastane-type diterpenes,named guanacastepenes P–T(1–5),were isolated from cultures of the fungus Psathyrella candolleana.Their structures were elucidated on the basis of extensive spectroscopic methods...; 关键词：Psathyrella candolleana Psathyrellaceae diterpenes Guanacastepenes P-T 11b-HSD1

国家自然科学基金(U1132607)