Project supported by the National Natural Science Foundation of China(No.11172158)
Duplication and divergence have been widely recognized as the two domi- nant evolutionary forces in shaping biological networks, e.g., gene regulatory networks and protein-protein interaction (PPI) networks. It has ...
supported by the National Natural Science Foundation of China(Grant Nos.31070954,11172158 and 10832006);the Shanghai Commission of Science and Technology Basic Research Fund(No.09JC1406600);the Shanghai Education Committee and Shanghai Leading Academic Discipline Project(J50103,key discipline"Molecular Physiology").
The self-renewal and multipotent potentials in neural stem cells(NSCs)maintain the normal physiological functions of central nervous system(CNS).The ab-normal differentiation of NSCs would lead to CNS disorders.Howeve...