国家自然科学基金(s20132020)

作品数：5被引量：7H指数：1
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相关作者：肖强纪三郝赵玉芬巨勇更多>>
相关机构：清华大学更多>>
相关期刊：《Science China Chemistry》《Chemical Research in Chinese Universities》《有机化学》《Chinese Journal of Chemistry》更多>>
相关主题：POLYAMIDEESI-MSESIDERIVATIVESDAIDZEIN更多>>
相关领域：理学生物学更多>>
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Synthesis of Novel Phosphorylated Daidzein Derivatives and ESI Investigation on Their Non-Covalent Complexes with Lysozyme被引量：6
《Chinese Journal of Chemistry》2007年第7期1008-1013,共6页陈晓岚 石晓娜 屈凌波 袁金伟 卢建莎 赵玉芬 
Project supported by the National Natural Science Foundation of China （Nos. 20132020 and 20175026） and Henan Academic Foundation of Science and Technology.
Daidzein （7,4＇-dihydroxyisoflavone） was phosphorylated by a modified Atherton-Todd reaction. The structures of the five target product, were determined by X-ray, IR, NMR and ESI-MS. Electrospray ionization results ...
关键词：DAIDZEIN PHOSPHORYLATION ESI-MS non-covalent complex 
Studies on a Novel Minor-groove Targeting Artificial Nuclease:Synthesis and DNA Binding Behavior被引量：1
《Chemical Research in Chinese Universities》2007年第1期44-47,共4页YIN Qiang ZHANG Zhen ZHAO Yu-fen 
Supported by the National Natural Science Foundation of China(Nos 20132020 and 20572061), the National Science andTechnology Committee of China, the National Ministry of Education of China, and Tsinghua University
Nucleases play an important role in molecular biology, for example, in DNA sequencing. Synthetic polyamide conjugates can be considered as a novel tool for the selective inhibition of gene expressions and also as pote...
关键词：Calf thymus DNA POLYAMIDE BIOCONJUGATE UV-Vis spectroscopy Circular dichroism 
Electrospray Ionization Mass Spectral Characteristics of Polyamide Containing 1,4,7,10-Tetraazacyclododecane
《Chinese Journal of Chemistry》2006年第7期923-928,共6页乔仁忠 张祯 巨勇 夏传琴 余孝其 赵玉芬 
Project supported by the National Natural Science Foundation of China （Nos. 20132020, 20572008）
The study of the fragmentations of the protonated molecular species [M＋H]^＋ and selected fragment ions allowed proposals for the main fragmentation pathways of the title compound. In order to better understand the f...
关键词：POLYAMIDE 1 4 7 10-TETRAAZACYCLODODECANE mass spectrometry 
通过酯交换方法简便地合成对称氢亚磷酸酯
《有机化学》2003年第z1期192-,共1页纪三郝 肖强 巨勇 赵玉芬 
国家自然科学基金(Nos.20132020,20172033)资助项目.
　　磷酸酯桥连的糖结构在生物体内广泛存在,例如在糖蛋白的多糖片断中普遍存在磷酸酯桥连的糖单元.在合成这类天然产物时,通常用到的方法包括氢亚磷酸酯方法和磷酰胺方法.在研究合成糖的磷酸酯缀合物时,我们想要合成对称的葡萄糖亚磷酸...
Penta-coordinate phosphorous compounds and biochemistry
《Science China Chemistry》2002年第4期337-348,共12页林长学 韩波 赵玉芬 万荣 李艳梅 冯亚兵 成昌梅 
This work was supported by the National Natural Science Foundation of China (Grant Nos. 20132020 and 20175026).
The relationship between penta-coordinate phosphorus compounds and biochemistry is briefly reviewed. Some interesting phenomena such as peptide formation, ester formation, ester exchange on phosphorus and N to O migra...
关键词：penta-coordinate phosphorus compounds BIOCHEMISTRY NUCLEOTIDE amino acid origin of life 
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