Funding Project for Academic Human Resources Development in Institutions of Higher Learning under the Jurisdiction of Beijing Municipality PHR (IHLB);National Natural Science Foundation of China (NSFC) (10801005) and (NSFC) (10771010);the Intramural Research Program of the National Institute of Child Health and Human Development,National Institute of Health
Problems of the simultaneous optimal estimates and the optimal tests in general mixed models are considered. A necessary and sufficient condition is presented for the least squares estimate of the fixed effects and th...