国家自然科学基金(30725045)

作品数：10被引量：65H指数：5
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相关作者：张卫东陈铭刘建华严诗楷金慧子更多>>
相关机构：第二军医大学上海交通大学中国药科大学更多>>
相关期刊：《Chinese Journal of Natural Medicines》《天然产物研究与开发》《Chemical Research in Chinese Universities》《Journal of Pharmaceutical Analysis》更多>>
相关主题：化学成分英文HPLC-DADNEWALKALOIDS更多>>
相关领域：理学生物学医药卫生农业科学更多>>
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藏波罗花的化学成分研究(英文)被引量：3
《天然产物研究与开发》2013年第3期325-328,共4页高燕萍 沈云亨 高燕霞 李博 张卫东 
Project supported by program NCET Foundation,NSFC(30725045)
从藏波罗花全草80%乙醇提取物中分离得到10个化合物,通过波谱学方法及参考文献对照分别鉴定为regyol(1)、长管假茉莉素B(2)、β-skytanthine(3)、deacyl isomartynoside(4)、对羟基苯乙醇(5)、rengioside B(6)、β-谷甾醇(7)、cleroindi...
关键词：藏波罗花 乙醇提取物 化学成分 
Cytotoxic terpenes from Abies sibirica被引量：2
《Chinese Chemical Letters》2012年第11期1251-1253,共3页Gui Rong Wang Yong Li Li Wei Dong Zhang Xian Wen Yang Wen Cong Liu Ji Ye Zhi Jun Zhu Hong Chen 
supported by program NCET Foundation;NSFC(No.30725045);partially supported by Global Research Network for Medicinal Plants(GRNMP);King Saud University,Shanghai Leading Academic Discipline Project(No.B906),FP7- PEOPLE-IRSES-2008(TCMCANCER Project 230232);Key Laboratory of Drug Research for Special Environments,PLA,Shanghai Engineering Research Center for the Preparation of Bioactive Natural Products(No.10DZ2251300);the Scientific Foundation of Shanghai China(No.09DZ1975700,09DZ1971500, 10DZ1971700);the Twelfth Five-Year National Science & Technology Support Program(No.2012BAI29B06)
One new and 16 known compounds were isolated from Abies sibirica. Their structures were assigned mainly on the basis of NMR and MS spectroscopic data. In bioassay for anti-proliferative activity against four human tum...
关键词：Abies sibirica PINACEAE TERPENES TRITERPENE 
采用GC-MS及RRLC-Q-TOFMS法分析中药复方附子理中丸的化学成分(英文)被引量：10
《中国天然药物》2011年第4期267-273,共7页刘慧 苏娟 杨茜 何雅君 李海云 叶霁 张卫东 
supported by the program NCET Foundation,NSFC(No.30725045);the Special Program for New Drug Innovation of the Ministry of Science and Technology,China(Nos.2009ZX09311-001,2009ZX09308-005)~~
目的:定性分析中药复方附子理中丸中的化学成分。方法:采用GC-MS和RRLC-Q-TOFMS的方法分别建立附子理中丸的指纹图谱,并对色谱峰进行定性分析。并采用系统聚类分析法对指纹图谱进行分类研究。结果:定性了附子理中丸中的45个成分,依据指...
关键词：GC-MS RRLC-Q-TOFMS 附子理中丸 指纹图谱 
Identification and determination of the major constituents in traditional Chinese medicine Longdan Xiegan Pill by HPLC-DAD-ESI-MS被引量：5
《Journal of Pharmaceutical Analysis》2011年第1期1-7,共7页Hui Liu Juan Su Xu Liang Xi Zhang Ya-Jun He Hai-Qiang Huan Ji Ye Wei-Dong Zhang 
supported by program NCET Foundation,NSFC(30725045);the Special Program for New Drug Innovation of the Ministry of Science and Technology,China(2009ZX09311-001,2008ZX09101-Z-029);Shanghai Leading Academic Discipline Project(B906);by the Scientific Foundation of Shanghai,China(07DZ19728,09DZ1975700,09DZ1971500)
A novel and sensitive HPLC-UV method has been developed for the simultaneous determination of twelve major compounds in Longdan Xiegan Pill.The chemical profile of the twelve compounds,including geniposidic acid（1）,...
关键词：Longdan Xiegan Pill high-performance liquid chromatography-diode array detector coupled with an electrospray tandem mass spectrometer（HPLC-DAD-ESI-MS） qualitative evaluation aristolochic acid A hierarchical cluster analysis 
Qualitative and Quantitative Analysis of Alkaloids in Cortex Phellodendri by HPLC-ESI-MS/MS and HPLC-DAD被引量：19
《Chemical Research in Chinese Universities》2011年第1期38-44,共7页ZHU Shuang-lai DOU Sheng-shan LIU Xin-ru LIU Run-hui ZHANG Wei-dong HUANG Hong-lin ZHANG Yi HU Yao-hua WANG Shu-ping 
Supported by the National Natural Science Foundation of China(No30725045);the Foundation of Eleventh Five-Year-Plan of China(No2008ZX09202-002);the Shanghai Leading Academic Discipline Project, China(NoB906);the Scientific Foundation of Shanghai City, China(No07DZ19702)
A combined method of high performance liquid chromatograph-elecrtrospray-ionization mass spectrometer（HPLC-ESI-MS/MS） coupled with a photodiode array detector（HPLC-DAD） and principal component analysis（PCA） was ...
关键词：Cortex Phellodendri ALKALOID HPLC-ESI-MS/MS Quantitative analysis Qualitative analysis Principal component analysis 
Rapid Quantification of Chinese Medicine Zuo Jin Pill via RRLC
《Chemical Research in Chinese Universities》2010年第6期905-909,共5页LIANG Xu ZHANG Xi XU Zhi-xiu LIU Hui HE Ya-jun LUE Yong-hai ZHANG Wei-dong 
Supported by the National Natural Science Foundation of China(No.30725045);the Special Program for New Drug Innovation of the Ministry of Science and Technology,China(Nos.2009ZX09311-001 and 2008ZX09101-Z-029);China Postdoctoral Science Foundation(No.20080441304);Shanghai Leading Academic Discipline Project,China(No.B906);the Scientific Foundation of Shanghai City,China(Nos.07DZ19728,09DZ1975700 and 09DZ1971500)
A rapid method based on rapid resolution liquid chromatography（RRLC） coupled with a diode array detector（DAD） was developed for the simultaneous determination of six major constituents（magnoflorine,jatrorrhizine,...
关键词：Zuo Jin Pill Rapid resolution liquid chromatography Simultaneous analysis Quality control Hierarchical cluster analysis 
Qualitative and Quantitative Analysis for the Quality Control of Rhizoma Coptidis by HPLC-DAD and HPLC-ESI-MS被引量：1
《Chemical Research in Chinese Universities》2010年第5期735-741,共7页DOU Sheng-shan ZHU Shuang-lai DAI Wei-xing ZHANG Wei-dong ZHANG Yi LIU Run-hui 
Supported by the National Natural Science Foundation of China(No.30725045);Shanghai Leading Academic Discipline Project (No.B906);in part by the Scientific Foundation of Shanghai China(Nos.07DZ19728, 06DZ19717 and 06DZ19005)
For quality control purpose, an approach of fingerprinting and simultaneous quantification of five major bioactive constituents of Rhizoma Coptidis was established via a high-performance liquid chromatograph coupled w...
关键词：Rhizoma Coptidis HPLC-DAD HPLC-MS Partial least squares analysis Quality control 
艾纳香黄酮类化学成分的研究(英文)被引量：18
《天然产物研究与开发》2010年第6期991-994,共4页陈铭 金慧子 严岚 扈晓佳 覃江江 刘建华 严诗楷 张卫东 
supported by program for Changjiang Scholars and Innovative Research Team in University(PCSIRT),NCET Foundation;NSFC(30725045);National 863 Program(2006AA02Z338);China Postdoctoral Science Foundation(20070410711);"973"program of China(2007CB507400);ShanghaiLeading Academic Discipline Project(B906);by the Scientific Foundation of Shanghai China(07DZ19728,06DZ19717,06DZ19005)
从艾纳香（Blumea balsamiferaDC.）的地上部分中分离得到13个黄酮类化合物,经鉴定分别为5,7-二羟基-3,3′,4′-三甲氧基黄酮（1）,3,5,3′,4′-四羟基-7-甲氧基黄酮（2）,4,2′,4′-三羟基双氢查尔酮（3）,儿茶素（4）,阿亚黄素（5）,d...
关键词：艾纳香 化学成分 黄酮 
A new nor-sesquiterpene lactone from Ainsliaea fulvioides被引量：2
《Chinese Chemical Letters》2009年第5期586-588,共3页Yan Wang Ming Lu Xu Hui Zi Jin Jian Jun Fu Xiao Jia Hu Jiang Jiang Qin Shi Kai Yan Yun Heng Shen Wei Dong Zhang 
supported by program for Changjiang Scholars and Innovative Research Team in University(PCSIRT),NCET Foundation,NSFC(No.30725045);National 863 Program(No.2006AA02Z338);China Postdoctoral Science Foundation(No.20070410711);"973"program of China(No.2007CB507400);Shanghai Leading Academic Discipline Project(No.B906);in part by the Scientific Foundation of Shanghai China(Nos.07DZ19728,06DZ19717,06DZ19005).
A new nor-sesquiterpene lactone ainsliatone A （1） was isolated from the aerial parts of Ainsliaeafulvioides. Its structure was established by the basis of spectroscopic methods and single-crystal X-ray diffraction a...
关键词：Ainsliaea fulvioides Ainsliatone A Nor-sesquiterpene lactone X-ray diffraction 
A new caffeic ester from Incarvillea mairei var.granditlora (Wehrhahn) Grierson被引量：6
《Chinese Chemical Letters》2008年第7期829-831,共3页Yong Qing Su Wei Dong Zhang Chuan Zhang Run Hui Liu Yun Heng Shen 
program for Changjiang Scholars and Innovative Research Team in University (PCSIRT),NCET Foundation,NSFC (No.30725045);National 863 Program (No.2006AA02Z338);Shanghai Leading Academic Discipline Project (No.B906);the Scientific Foundation of Shanghai China (No.07DZ19728,06DZ19717,06DZ19005).
A new cafferic ester, （＋）-2-（1-hydroxyl-4-oxocyclohexyl） ethyl caffeate, was isolated from the 80% ethanol extract of the whole plants of Incarvillea mairei var. granditlora （Wehrhahn） Grierson. The structure o...
关键词：Incarvillea mairei var. granditlora BIGNONIACEAE Caffeic ester Ethyl caffeate 
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