supported by the National Basic Research Program of China(2012CBA01300 and2012CB966500)
Mouse embryonic stem cells(mESCs)derived from inner cell mass(ICM)of pre-implantation embryos,can maintain undifferentiated state when cultured in N2B27 medium supplemented with GSK3inhibitor CHIR99021 and MEK inhibit...
supported by the National Key Basic Research Program of China(2012CB966500,2013CB-967100);the National Natural Science Foundation of China(31201112)
The androgenetic embyronic stem (aES) cells are useful models in studying the effects of imprinted genes on pluripotency maintaining and embryo development. The expression patterns of imprinted genes are significantly...
supported by grants from the National Basic Research Program of China(Grant No.2012CBA01300 and 2012CB966500)
Induced pluripotent stem (iPS) cells can be generated by forced expression of four pluripotency factors in somatic cells. This has received much attention in recent years since it may offer us a promising donor cell...