云南高校图书馆联盟文献共享服务平台- 国家重点基础研究发展计划(2011CB944100)

国家重点基础研究发展计划(2011CB944100): 作品数：12被引量：36H指数：4; 导出分析报告; 相关作者：于军潘林林周媛媛龚未胡松年更多>>; 相关机构：中国科学院大学中国科学院更多>>; 相关期刊：《中国科学：生命科学》《Science China(Life Sciences)》《Genomics, Proteomics & Bioinformatics》《Journal of Genetics and Genomics》更多>>; 相关主题：TRANSCRIPTOMEARTEMIADEVELOPMENTDEVELOPINGUSING更多>>; 相关领域：生物学农业科学医药卫生更多>>

A 2-bp insertion(c.6768insCC) in MC1R causes recessive white coat color in Bama miniature pigs被引量：6: 《Journal of Genetics and Genomics》2017年第4期215-217,共3页Qitao Jia Chunwei Cao Hai Tang Ying Zhang Qiantao Zheng Xiao Wang Rui Zhang Xianlong Wang Ailing Luo Hong Wei Anming Meng Qi Zhou Hongmei Wang Jianguo Zhao; supported by the National Basic Research Program of China (Nos. 2011CBA0100, 2011CB944100, 2011BAI15B02, and se2012BAI39B04);the National High Technology Research and Development Program of China (No. 2012AA020602);the Strategic Priority Research Program of CAS (Nos. XDA08000000 and XDA01030400);the National Natural Science Foundation of China (Nos. 31272440 and 81671274); Coat color is an important characteristic of various breeds of domestic animal species.Variation in farm animal coat color is of considerable interest for concealment,communication and protection against solar radiat...; 关键词：miniature recessive c.67_68insCC insertion physiological mutant originally phenotype spots linkage

Human Pharyngeal Microbiome May Play A Protective Role in Respiratory Tract Infections被引量：2: 《Genomics, Proteomics & Bioinformatics》2014年第3期144-150,共7页Zhancheng Gao Yu Kang Jun Yu Lufeng Ren; supported by the National High Technology Research and Development Program of China (863 Program, Grant No. 2006AA02Z4A9);the National Basic Research Program of China (973 Program, Grant No. 2011CB944100); The human pharyngeal microbiome, which resides at the juncture of digestive and respiratory tracts, may have an active role in the prevention of respiratory tract infections, similar to the actions of the intestinal m...; 关键词：Respiratory tract infections Pharyngeal microbiome HOMEOSTASIS PROBIOTICS Restoration balance ofmicrobiome

Transcriptomic analysis reveals key regulators of mammogenesis and the pregnancy-lactation cycle被引量：4: 《Science China(Life Sciences)》2014年第3期340-355,共16页ZHOU YuanYuan GONG Wei XIAO JingFa WU JiaYan PAN LinLin LI XiaoNuan WANG XuMin WANG WeiWei HU SongNian YU Jun; supported by grant from Ministry of Science and Technology of China (2011CB944100,2011CB944101); An organ unique to mammals, the mammary gland develops 90% of its mass after birth and experiences the pregnancy-lactation-involution cycle （PL cycle） during reproduction. To understand mammogenesis at the transcrip...; 关键词：mouse mammary gland mammogenesis TRANSCRIPTOME rmRNA-seq miRNAs transcription factors

小鼠乳腺发育的转录组学研究--怀孕哺乳周期乳腺的关键调控基因被引量：2: 《中国科学：生命科学》2014年第3期291-306,共16页周媛媛龚未肖景发吴佳妍潘林林李小暖王绪敏王伟伟胡松年于军; 国家重点基础研究发展计划(批准号:2011CB944100,2011CB944101)资助项目; 乳腺是哺乳动物特有的器官,90%的发育过程集中在出生之后.此外,在生殖过程中乳腺发育会经历怀孕、哺乳和退化3个阶段(称为怀孕哺乳周期).为了在转录组水平上更好地了解乳腺发育的机制,利用核糖体RNA去除法构建了小鼠乳腺3个时期(怀孕12...; 关键词：小鼠乳腺乳腺发育转录组 rmRNA—seq MIRNAS 转录因子

Systematic analysis of intron size and abundance parameters in diverse lineages被引量：6: 《Science China(Life Sciences)》2013年第10期968-974,共7页WU JiaYan XIAO JingFa WANG LingPing ZHONG Jun YIN HongYan WU ShuangXiu ZHANG Zhang YU Jun; supported by the National Natural Science Foundation of China(31101063,31271386);National Basic Research Program of China(2010CB126604,2011CB944100,2011CB944101); All eukaryotic genomes have genes with introns in variable sizes.As far as spliceosomal introns are concerned,there are at least three basic parameters to stratify introns across diverse eukaryotic taxa:size,number,an...; 关键词：spliceosomal intron intron length distribution minimal intron splice protein LINEAGE

Mitochondrial genome sequences of Artemia tibetiana and Artemia urmiana:assessing molecular changes for high plateau adaptation被引量：5: 《Science China(Life Sciences)》2013年第5期440-452,共13页ZHANG HangXiao LUO QiBin SUN Jing LIU Fei WU Gang YU Jun WANG WeiWei; supported by the National Natural Science Foundation of China(30221004)to Wang WeiWei;the National Basic Research Program from Ministry of Science and Technology of China(2011CB944100)to Yu Jun; Brine shrimps,Artemia(Crustacea,Anostraca),inhabit hypersaline environments and have a broad geographical distribution from sea level to high plateaus.Artemia therefore possess significant genetic diversity,which give...; 关键词：mitochondrial genome Artemia tibetiana sequence variation high plateau species

线粒体全基因组测序探寻高原环境对Artemia tibetiana和A．urmiana卤虫种线粒体基因的影响: 《中国科学：生命科学》2013年第4期319-331,共13页张航晓罗奇斌孙婧刘飞吴刚于军王伟伟; 国家自然科学基金(批准号:30221004);国家重点基础研究发展计划(批准号:2011CB944100)资助项目; 卤虫(Artemia)属甲壳纲无背甲目,生活于高盐环境中,低海拔和高海拔地区均有分布,在适应不同环境需求的过程中形成了遗传的多样性.为研究卤虫表型的可塑性,本研究对2个来自青藏高原的A.tibetiana和1个来自伊朗乌尔米耶湖的A.urmiana的线...; 关键词：线粒体基因组 ARTEMIA tibetiana序列变化高原物种

MeRIP-PF:An Easy-to-use Pipeline for High-resolution Peak-finding in MeRIP-Seq Data被引量：2: 《Genomics, Proteomics & Bioinformatics》2013年第1期72-75,共4页Yuli Li Shuhui Song Cuiping Li Jun Yu; supported by Grants from the Ministry of Science and Technology of China (Grant No. 2011CB944100) to JY;the Natural Science Foundation (Grant No. 30900831 and 31271372);Beijing Nova Program (Grant No. Z121105002512060)to SS; RNA modifications, especially methylation of the N6 position of adenosine （A）--m6A, rep- resent an emerging research frontier in RNA biology. With the rapid development of high-throughput sequencing technology, in-d...; 关键词：RNA modification m 6A Peak finding MeRIP-Seq

基于新一代测序方法的小鼠睾丸出生后发育的转录组研究被引量：2: 《中国科学：生命科学》2013年第2期137-150,共14页龚未潘林林林强周媛媛辛成齐俞晓敏崔鹏胡松年于军; 国家重点基础研究发展计划(批准号:2011CB944100;2011CB944101);国家自然科学基金(批准号:90919024);科技部科技基础工作专项(批准号:2009FY120100);国家高技术研究发展计划(批准号:2012AA020409)资助项目; 哺乳动物睾丸的发育是一个高度复杂而精密的过程.为了从转录组水平研究睾丸正常发育过程中的动态变化,本实验选取了出生后6日龄、4周龄和10周龄的3组小鼠,分别代表其幼年期、青春期以及成年期.应用超高通量的新一代测序技术(RNA-seq),...; 关键词：新一代测序转录组小鼠睾丸发育

Transcriptome profiling of the developing postnatal mouse testis using next-generation sequencing被引量：9: 《Science China(Life Sciences)》2013年第1期1-12,共12页GONG Wei PAN LinLin LIN Qiang ZHOU YuanYuan XIN ChengQi YU XiaoMin CUI Peng HU SongNian YU Jun; supported by the National Basic Research Program of China(2011CB944100,2011CB944101);the National Natural Science Foundation of China (90919024);the Special Foundation Work Program of Ministry of Science and Technology (2009FY120100);the National High Technology Research and Development Program of Ministry of Science and Technology of China (2012AA020409); Mammalian testis development is a complex and highly sophisticated process. To study the dynamic change of normal testis development at the transcriptional level, we investigated mouse testes at three postnatal ages: ...; 关键词：next-generation sequencing TRANSCRIPTOME mouse testis DEVELOPMENT

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