In the current era,with rapid advancements in medical technology and an aging population,critical care medicine stands as a shining star within the medical field,its significance growing ever more prominent.The global...
Acute kidney injury(AKI)presents a significant challenge in the management of critically ill patients,as it is as-sociated with increased mortality,prolonged hospital stays,and increased healthcare costs.In certain co...
Aminoglycosides are concentration-dependent antibiotics exerting a bactericidal effect when concentrations at the site of infection are equal to or greater than 5 times the minimum inhibitory concentrations(MIC).When ...
This review summarizes the current research advances and guideline updates in neurocritical care. For the therapy of ischemic stroke, the extended treatment time window for thrombectomy and the emergence of novel thro...
Septic shock is associated with severe vasoplegia, increased permeability, maldistribution of regional blood flows, and microvascular alterations. Hemodynamic management includes fluid and vasopressor agents and, in s...
funded by the National Science and Technology Major Project of China(2022YFC2504505);Jiangsu Provincial Key Research and Development Program(BE2022854);National Key Research and Development Program of China(2022YFC2504400).
Background:Extracorporeal membrane oxygenation(ECMO)has been proven to be a support method and technology for patients with cardiopulmonary failure.However,the transport of patients under ECMO support is challenging g...
supported by National Clinical Key Specialty(grant number:Z155080000004));Clinical management optimization project of SHDC(grant number:SHDC22022206).
Background:Awake prone positioning(APP)can reportedly reduce the need for intubation and help improve prognosis of patients with acute hypoxemic respiratory failure(AHRF)infected with COVID-19.However,its physiologica...
supported by the Anhui Provincial Special Project of Central Government Guiding Local Science and Technology Development of China(grant number:201907d07050001);Anhui Provincial Natural Science Foundation(grant number:2108085MH300);Funding of“Peak”Training Program for Scientific Research of Yijishan Hospital,Wannan Medical College(grant numbers:GF2019J03,GF2019G08);Anhui Provincial Clinical Medical Research and Translational Project(grant numbers:202304295107020006,202304295107020001).
Background:The purpose is to formulate a modified screening protocol for acute respiratory distress syndrome(ARDS)in patients with respiratory support based on saturation of pulse oximetry(SpO_(2))and inspired oxygen ...
project is co-funded by the PPP allowance to stimulate public-private partnership made available by Health~Holland,Top Sector Life Sciences&Health,as well as by a contribution from the Dutch Burns Foundation(grant number:nr LSHM 17077-SGF)www.health-holland.com.
Background:Severe burns induce volume shifts via capillary leaks,eventually requiring massive fluid resuscitation and promoting tissue edema.Albumin may help to mitigate the edema,thereby improving perfusion.This stud...
Background:Cancer patients who are exposed to sepsis and had previous chemotherapy may have increased severity. Among chemotherapeutic agents, anthracyclines have been associated with cardiac toxicity. Like other chem...