Background:Cancer patients who are exposed to sepsis and had previous chemotherapy may have increased severity. Among chemotherapeutic agents, anthracyclines have been associated with cardiac toxicity. Like other chem...
Due to advances in modern tumor treatments, patients can survive long-term. However, cardiotoxicity caused by tumor therapy poses a significant challenge to both physicians and patients. Early detection and accurate a...
supported by grants from the Beijing Hospitals Authority Youth Programme,China(No.QML20231602);the Young Elite Scientist Sponsorship Program by Beijing Association for Science and Technology(BAST)(No.BYESS2023226).
Objective Anthracycline-containing regimens are irreplaceable in neoadjuvant chemotherapy(NAC)for breast cancer(BC)at present.However,30% of early breast cancer(EBC)patients are resistant to anthracycline-containing c...
the Hubei Province Health and Famliy Planning Scientific Research Project(No.WJ2023M011);the Department of Finance of Hubei Province(No.3890750).
Objective Anthracycline chemotherapeutic agents have significant cardiotoxicity.The present study emphasized the effect of anthracycline chemotherapy drugs on left ventricular(LV)myocardial stiffness in breast cancer ...
National Key Research and Development Program(No.2018YFC1704901)。
Objective:To systematically evaluate the therapeutic effect of TCM on cardiotoxicity induced by anthracycline chemotherapy to provide clinical guidance.Methods:China hownet database(CNKI),Chinese biomedical literature...
All-trans retinoic acid(ATRA)and pre-upfront arsenic trioxide(ATO)have revolutionized the therapy of acute promyelocytic leukemia(APL).However,internal tandem duplication of FMS-like tyrosine kinase 3(FLT3-ITD)mutatio...
This research was supported by the National Natural Science Foundation of China(81530100 and 81822049).
Objective:To evaluate the effect of traditional Chinese medicine(TCM)on anthracycline-induced cardiotoxicity(AIC)in animal models.Methods:Separate systematic searches for preclinical studies were performed in the PubM...
BACKGROUND Doxorubicin and other anthracycline derivatives inhibit topoisomerase II and is an important class of cytotoxic chemotherapy in cancer treatment.The use of anthracycline is limited by dose-dependent cardiot...
The Hope Foundation and the Robert and Heather Urich Foundation.
Aim:Cardiovascular disease is a leading cause of mortality among long-term cancer survivors treated with large total doses of doxorubicin.An increase in coronary artery disease(CAD)among childhood cancer survivors by ...
BACKGROUND Cardiovascular side effects occur frequently during anti-cancer treatment, and there is a growing concern that they may lead to premature morbidity and death. CASE SUMMARY A 32-year-old woman was diagnosed ...