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《Cancer Innovation》: 作品数：130被引量：35H指数：2; 导出分析报告; 主办单位：清华大学; 最新期次：2024年6期更多>>; 发文主题：IMMUNOTHERAPYCANCERBREAST_CANCERIMMUNEINHIBITORS更多>>; 发文领域：医药卫生文化科学自动化与计算机技术更多>>; 发文基金：国家自然科学基金中国博士后科学基金广东省自然科学基金更多>>

Combination therapy using low‐dose anlotinib and immune checkpoint inhibitors for extensive‐stage small cell lung cancer: 《Cancer Innovation》2024年第6期76-85,共10页Han Li Shumin Yuan Han Wu Yajie Wang Yichen Ma Xiance Tang Xiaomin Fu Lingdi Zhao Benling Xu Tiepeng Li Peng Qin Hongqin You Lu Han Zibing Wang; National Natural Science Foundation of China,Grant/Award Number:81972690;Medical Science and Technology Research Project of Health Commission of Henan Province,Grant/Award Number:YXKC2021007。; Background:This study evaluated the efficacy and safety of low‐dose anlotinib combined with immune checkpoint inhibitors as second‐line or later treatment for extensive‐stage small cell lung cancer(ES‐SCLC).Method...; 关键词：combination immunotherapy extensive‐stage small cell lung cancer immune checkpoint inhibitors low‐dose antiangiogenic drugs

Prognostic nomograms for young breast cancer:A retrospective study based on the SEER and METABRIC databases: 《Cancer Innovation》2024年第6期86-99,共14页Yongxin Li Xinlong Tao Yinyin Ye Yuyao Tang Zhengbo Xu Yaming Tian Zhen Liu Jiuda Zhao; Provincial‐Level Clinical Key Specialty Construction in Qinghai Province。; Background:Young breast cancer(YBC)is a subset of breast cancer that is often more aggressive,but less is known about its prognosis.In this study,we aimed to generate nomograms to predict the overall survival(OS)and b...; 关键词：breast cancer‐specific survival NOMOGRAM overall survival prognostic model young breast cancer

TRIP13:A promising cancer immunotherapy target: 《Cancer Innovation》2024年第6期1-10,共10页Shengnan Jing Liya Zhao Liwen Zhao Yong‐Jing Gao Tianzhen He; Large Instruments Open Foundation of Nantong University,Grant/Award Number:KFJN2375;National Natural Science Foundation of China,Grant/Award Number:82100557。; The tumor microenvironment(TME)facilitates tumor development through intricate intercellular signaling,thereby supporting tumor growth and suppressing the immune response.Thyroid hormone receptor interactor 13(TRIP13)...; 关键词：immune responses immune‐based therapies thyroid hormone receptor interactor 13 tumor microenvironment

Impact of metallic nanoparticles on gut microbiota modulation in colorectal cancer:A review: 《Cancer Innovation》2024年第6期11-28,共18页Akash Kumar Jhilam Pramanik Kajol Batta Pooja Bamal Mukesh Gaur Sarvesh Rustagi Bhupendra G.Prajapati Sankha Bhattacharya; Colorectal cancer(CRC)is the third most prevalent cancer.Ongoing research aims to uncover the causes of CRC,with a growing focus on the role of gut microbiota(GM)in carcinogenesis.The GM influences CRC development,pro...; 关键词：APOPTOSIS CARCINOGENESIS DYSBIOSIS gastrointestinal microbiome titanium dioxide

Leukocyte immunoglobulin‐like receptor B4:A keystone in immune modulation and therapeutic target in cancer and beyond: 《Cancer Innovation》2024年第6期29-41,共13页Qi Liu Yuyang Liu Zhanyu Yang; Leukocyte immunoglobulin‐like receptor B4(LILRB4)significantly impacts immune regulation and the pathogenesis and progression of various cancers.This review discusses LILRB4's structural attributes,expression pattern...; 关键词：cancer therapy immune checkpoint immunotherapy leukocyte immunoglobulin‐like receptor B4 monoclonal antibodies

Retinoic acid receptor responder 2 and lipid metabolic reprogramming:A new insight into brain metastasis: 《Cancer Innovation》2024年第6期42-44,共3页Lulu Wang Yan Gao; The brain is one of the most common metastatic sites for carcinoma,especially for breast cancer,the second leading cause of brain metastases(BrM)after lung cancer[1].During organ‐tropic metastases,cancer cells have t...; 关键词：brain metastases breast cancer lipid metabolism retinoic acid receptor responder 2

Development and validation of the NCC‐BC‐A scale to assess patient‐reported outcomes for breast cancer patients in China: 《Cancer Innovation》2024年第6期45-57,共13页Fei Ma Xiaoyan Yan Xiuwen Guan Tianmou Liu 无; CAMS Innovation Fund for Medical Sciences,Grant/Award Number:2021‐I2M‐1‐014。; Background:The commonly used international patient‐reported outcome scales for breast cancer were developed before the advent of multiple targeted therapies and immunotherapies,rendering them potentially insufficient...; 关键词：breast cancer patient‐reported outcome quality of life

Beyond clinical trials:CDK4/6 inhibitor efficacy predictors and nomogram model from real‐world evidence in metastatic breast cancer: 《Cancer Innovation》2024年第6期58-75,共18页Binliang Liu Zhe‐Yu Hu Ning Xie Liping Liu Jing Li Xiaohong Yang Huawu Xiao Xuran Zhao Can Tian Hui Wu Jun Lu Jianxiang Gao Xuming Hu Min Cao Zhengrong Shui Yu Tang Quchang Ouyang; Hunan Provincial Natural Science Foundation of China,Grant/Award Numbers:2023JJ60334,2023JJ60464,2024JJ6289;Beijing Science and Technology Innovation Medical Development Foundation,Grant/Award Number:KC2023‐JX‐0082‐05;The Climb Plan of Hunan Cancer Hospital,Grant/Award Numbers:QH2023006,ZX2021005。; Background:CDK4/6 inhibitors(CDK4/6i)have shown promising results in the treatment of hormone receptor‐positive(HR+)metastatic breast cancer(MBC)when combined with endocrine therapy(ET).It is crucial to evaluate the ...; 关键词：breast cancer CDK4/6 inhibitor EFFICACY predictive factors real‐word study

A pan‐cancer analysis of Wnt family member 7B in human cancers: 《Cancer Innovation》2024年第5期84-101,共18页Rui Wang Ni‐sha Wu Li Wang Zhi‐zhao Zhang Cheng‐fang Wang Yan Wang Yan Liang Yi Zhang Xiao‐wei Qi; sub‐project of the National Key R&D Program of China,Grant/Award Number:2022YFC2403401;Chongqing Talents Project,Grant/Award Number:414Z393;Program of Military Medical Staff Innovation Plan of Southwest Hospital,Grant/Award Number:2023DZXZZ004;Chongqing Key Project of Technology Innovation and Application Development,Grant/Award Number:CSTB2022TIAD‐KPX0168。; Background: Previous studies have highlighted the crucial role of Wnt7B inthe development of various cancers, including breast, pancreatic, and gastriccancers. However, research into the involvement of Wnt7B is often ...; 关键词：BIOINFORMATICS immune infiltration IMMUNOTHERAPY pan‐cancer analysis Wnt7B

《Cancer Innovation》