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Fifteen Pathways between Electric Vehicles and Public Health:A Transportation−Health Conceptual Framework: 《Environment & Health》2024年第12期848-853,共6页Chunyu Guo Becky P.Y.Loo Kuishuang Feng H.Oliver Gao Kai Zhang; The health impact of electric vehicles(EVs)is complex and multifaceted,encompassing reductions in air pollutants,improvements in road safety,and implications for social equity.However,existing studies often provide fr...; 关键词：LINKING TRANSPORTATION UNIFIED

Effect of Fluorine Atoms and Piperazine Rings on Biotoxicity of Norfloxacin Analogues:Combined Experimental and Theoretical Study: 《Environment & Health》2024年第12期886-901,共16页Chuanxi Yang Xiaoning Wang Xinyan Zhao Yongkun Wu Jingyan Lin Yuhan Zhao Yiyong Xu Kaipeng Sun Chao Zhang Ziheng Wan Weihua Zhao Yihua Xiao Haofen Sun Dong Chen Wenping Dong Tieyu Wang Weiliang Wang; To clarify the effect of the fluorine atom and piperazine ring on norfloxacin(NOR),NOR degradation products(NOR-DPs,P1−P8)were generated via UV combined with hydrogen peroxide(UV/H2O2)technology.NOR degradation did no...; 关键词：NORFLOXACIN biotoxicity inhibition effect molecular docking structure−activity relationship

Exposure to Multiple Endocrine-Disrupting Chemicals and Associations with Female Infertility:A Case-Control Study: 《Environment & Health》2024年第12期902-911,共10页Xianping Wei Na Zhang Qingqing Zhu Yu Hu Xin Wang Xueyu Weng Chunyang Liao Guibin Jiang; financially supported by the National Natural Science Foundation of China(22225605,22193051,and 22006103);the National Key Research and Development Program of China(2023YFC3706600 and 2022YFC2703303);the K.C.Wong Education Foundation of China(GJTD-2020-03);the Professor station of China Agricultural University at Xinzhou Center for Disease Control and Prevention.; Parabens(PBs)and their metabolites(MBs),triclocarban(TCC),triclosan(TCS),bisphenols(BPs),benzophenones(BzPs),and phthalate metabolites(mPAEs)are typical endocrine-disrupting chemicals(EDCs)used in industrial productio...; 关键词：Endocrine-disrupting chemicals Human exposure Female infertility SERUM ASSOCIATION

Evaluation of Machine Learning Based QSAR Models for the Classification of Lung Surfactant Inhibitors Published as part of Environment&Health special issue“Artificial Intelligence and Machine Learning for Environmental Health”: 《Environment & Health》2024年第12期912-917,共6页James Y.Liu Joshua Peeples Christie M.Sayes; J.Y.L.received student internship funds from the Oak Ridge Institute for Science and Education(ORISE)through an interagency agreement between the U.S.Department of Energy and the Air Force Research Laboratory(AFRL,AFRL-2023-4907);J.Y.L.and C.M.S.thank the Baylor Department of Environmental Science and the Henry F Jackson Foundation for financially supporting this research.; Inhaled chemicals can cause dysfunction in the lung surfactant,a protein-lipid complex with critical biophysical and biochemical functions.This inhibition has many structure-related and dose-dependent mechanisms,makin...; 关键词：machine learning QSAR lung surfactant hazard screening

Observed Effects on Very Early Pregnancy Linked to Ambient PM_(2.5) Exposure in China among Women Undergoing In Vitro FertilizationEmbryo Transfer: 《Environment & Health》2024年第12期918-928,共11页Changxin Lan Yichun Guan Haining Luo Xiaoling Ma Yihua Yang Hongchu Bao Cuifang Hao Xiaojin He Han Zhang Ning Gao Weinan Lin Mengyuan Ren Tianxiang Wu Chao Wang Xiaoqing Ni Chunyan Shen Jianrui Zhang Junfang Ma Rui Zhang Yin Bi Lili Zhuang Ruichao Miao Ziyi Song Tong An Zhengteng Liu Bo Pan Mingliang Fang Jing Liu Zhipeng Bai Fangang Meng Yuanchen Chen Xiaoxia Lu Yuming Guo Yunxia Cao Qun Lu Bin Wang; National Key Research&Development Program of Ministry of Science and Technology of China,No.2023YFC3708305(ZPB),2022YFE0134900(JL),and 2022YFC2704404(QL);National Natural Science Foundation of China,No.42077390(BW),41771527(BW);Yunnan Major Scientific and Technological Projects,No.202202AG050019(BP).; The adverse effect of ambient PM_(2.5) exposure on very early pregnancy(VEP)remains controversial among epidemiological studies but is supported by toxicological evidence.We adopted a multicenter retrospective cohort ...; 关键词：Fine particulate matter Very early pregnancy IVF-ET Biochemical pregnancy Clinical pregnancy

Very Early Pregnancy Loss:The Role of PM_(2.5) Exposure in IVF-ET Outcomes: 《Environment & Health》2024年第12期854-855,共2页Xinlei Zhu Haidong Kan; Air pollution,particularly fine particulate matter(PM_(2.5)),has long been recognized as a significant global environmental and public health concern.The detrimental effects of PM_(2.5) on human health are well-docume...; 关键词：POLLUTION offering EARLY

The Constituent-Dependent Translocation Mechanism for PM_(2.5) to Travel through the Olfactory Pathway: 《Environment & Health》2024年第12期856-864,共9页Sheng Wei Ting Xu Miao Cao Huan Wang Yiqun Song Daqiang Yin; supported by the National Natural Science Foundation of China(22236006,22076146,and 22036001)。; The neurotoxic risk of PM_(2.5) is of worldwide concern,but the pathways through which PM_(2.5) gets to the central nervous system are still under debate.The olfactory pathway provides a promising shortcut to the brai...; 关键词：particulate matter olfactory system central nervous system ENDOCYTOSIS vesicle transportation

Associations between Metals, Serum Folate, and Cognitive Function in the Elderly: Mixture and Mediation Analyses: 《Environment & Health》2024年第12期865-874,共10页Luli Wu Ye Xin Junrou Zhang Xin Yang Tian Chen Piye Niu; supported by the National Natural Science Foundation of China(No.81973007).; Exposure to metals may potentially impact cognitive health in the elderly;however,the evidence remains ambiguous.The specific role of serum folate in this relationship is also unclear.We aimed to evaluate the individu...; 关键词：METALS Cognitive function Serum folate Quantile g-computation Bayesian kernel machine regression Mediating effect

Balancing the Functionality and Biocompatibility of Materials with a Deep-Learning-Based Inverse Design Framework: 《Environment & Health》2024年第12期875-885,共11页Xiaofang Li Hanle Chen Jiachen Yan Guohong Liu Chengjun Li Xiaoxia Zhou Yan Wang Yinbao Wu Bing Yan Xiliang Yan; supported by the National Natural Science Foundation of China(22106025,22036002);the Introduced Innovative R&D Team Project under the“The Pearl River Talent Recruitment Program”of Guangdong Province(2019ZT08L387);the Basic and Applied Basic Research Foundation of Guangzhou,China(202201010541);the Guangdong Basic and Applied Basic Research Foundation(2022A1515111082).; The rational design of molecules with the desired functionality presents a significant challenge in chemistry.Moreover,it is worth noting that making chemicals safe and sustainable is crucial to bringing them to the m...; 关键词：inverse design biocompatible materials antibiotic-free strategy generative models virtual screening

Lung Single-Cell Transcriptomics Offers Insights into the Pulmonary Interstitial Toxicity Caused by Silica Nanoparticles: 《Environment & Health》2024年第11期786-801,共16页Yan Li Qing Yao Hailin Xu Jiaze Ren Yurou Zhu Caixia Guo Yanbo Li; supported by the National Natural Science Foundation of China(82273658,82173551);Special Funds for the Construction of High-level Public Health Technical Talents(xuekegugan-01-048).; The adverse respiratory outcomes motivated by silica nanoparticles(SiNPs)exposure have received increasing attention.Herein,we aim to elucidate the interplay of diverse cell populations in the lungs and key contributo...; 关键词：silica nanoparticles single-cell RNA-Seq lung toxicity lung interstitial disease PROTEOSTASIS

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