With the increasingly widespread application of traditional Chinese medicine in clinical practice,the safety of traditional Chinese medicine has been given more attention.The occurrence of adverse drug reactions of tr...
supported by the National Natural Science Foundation of China(Grants no.82060754,81803838);The ability establishment of sustainable use for valuable Chinese medicine resources(2060302);Science and technology project of Guizhou health and Health Committee(gzwkj2021-441);Science and Technology Department of Honghuagang District of Zunyi city of Guizhou province of China([2020]-17);Zunyi Medical University Postgraduate Research Fund(ZYK187).
Background:Cantharidin(CTD)is a commonly used natural product with anticancer properties;however,it has significant adverse effects,particularly hepatotoxicity.Glycyrrhetinic acid(GA),the active component of licorice,...
Background:To explore the effects and mechanisms of Bu-Yang-Huan-Wu Decoction on pulmonary fibrosis in mice.Methods:Forty-five C57BL/6J mice were randomly divided into three groups:Control,Model,and Bu-Yang-Huan-Wu De...
The research was financially supported by the National Natural Science Foundation of China(no.81760746);Science and Technology Department of Zunyi city of Guizhou province of China([2020]7);Guizhou Provincial Science&Technology Program(ZK[2022]615).
Background:Magnesium cantharidate(MC)is a protein phosphatase 2A(PP2A)inhibitor antitumor drug.However,its antitumor mechanism in hepatocellular carcinoma cell(HCC)remains unclear.Methods:PP2A lentiviral vector over e...
The consumption of maize and cowpea in Africa and developing countries is high,owing to the fact that they are readily available,coupled the with nutritional benefits they provide.Growth loss has been seen in crops cu...
Background:Cucurbita maxima plant materials are frequently used to manage a number of disorders,according to previous studies.Objective:The goal of the present report was to look into further possible effects of this ...
Occupational exposure to flour dust within bakery environments presents significant health hazards to bakery personnel.Flour dust,generated as a byproduct during baking,becomes airborne during the baking process,thus ...
The soil environment is a reservoir of nutrients as well as pollutants,and because of this,most of our food items are ladened with lots of pollutants ranging from fertilizers,pesticides,herbicides to heavy metals(HM)....
Fishes are excellent markers of the extent of pollution from heavy metals in aquatic environments given that they are found at various levels of the food chain.This study aimed to investigate the bioaccumulation of he...
This work is funded by National Natural Science Foundation of China(No.81773466)to W.H,and by Beijing Key Laboratory of Metabolic Disorder Related Cardiovascular Disease(No.DXWL2023-06)to W.X.
Epigenetic modifications modulate conformational structure of chromatin and consequently gene expression by enzyme-mediated chemical modifications of DNA and histones.The activities of epigenetic modifying enzymes dep...