WINGLESS

作品数：23被引量：97H指数：5
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相关领域：生物学医药卫生更多>>
相关作者：陈婉沈杰林国南李志红朱丽更多>>
相关机构：山西大学南京师范大学中国科学院大学江苏开放大学更多>>
相关期刊：《Insect Science》《Journal of Oceanology and Limnology》《中国生物化学与分子生物学报》《昆虫学报》更多>>
相关基金：国家自然科学基金中国博士后科学基金湖北省自然科学基金“重大新药创制”科技重大专项更多>>
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Abnormally activated wingless/integrated signaling modulates tumor-associated macrophage polarization and potentially promotes hepatocarcinoma cell growth
《World Journal of Gastroenterology》2024年第41期4490-4495,共6页Wei-Lu Wang Paul Kwong Hang Tam Yan Chen 
Supported by Macao Science and Technology Development Fund,No.0086/2022/A and No.0097/2022/A2.
In this article,we comment on the article by Huang et al.The urgent development of new therapeutic strategies targeting macrophage polarization is critical in the fight against liver cancer.Tumor-associated macrophage...
关键词：Liver cancer Hepatocarcinoma cell Wingless/integrated signaling pathway M2 tumor-associated macrophages Polarization 
ZNF554 Inhibits Endometrial Cancer Progression via Regulating RBM5 and Inactivating WNT/β-Catenin Signaling Pathway被引量：1
《Current Medical Science》2024年第2期406-418,共13页Cheng-cheng ZHU Heng-liang SUN Teng-fei LONG Yuan-yuan LYU Jiang-li LIU Guan-tai NI 
supported by the Science-Technology Foundation for Middle-aged and Young Scientists of Wannan Medical College(No.WK2021F19);the 2023 Wannan Medical College Research Fund(No.WK2023ZZD18).
Objective:Uterine corpus endometrial carcinoma(UCEC),a kind of gynecologic malignancy,poses a significant risk to women’s health.The precise mechanism underlying the development of UCEC remains elusive.Zinc finger pr...
关键词：zinc finger protein 554 endometrial carcinoma RNA binding motif 5 Wingless/β-catenin signaling pathway 
Wingless/It/β-catenin signaling in liver metastasis from colorectal cancer:A focus on biological mechanisms and therapeutic opportunities被引量：3
《World Journal of Gastroenterology》2023年第18期2764-2783,共20页Federico Selvaggi Teresa Catalano Rossano Lattanzio Roberto Cotellese Gitana Maria Aceto 
The liver is the most common site of metastases in patients with colorectal cancer.Colorectal liver metastases(CRLMs)are the result of molecular mechanisms that involve different cells of the liver microenvironment.Th...
关键词：Wingless/It/β-catenin signaling Colorectal cancer Epithelial-mesenchymal transition/mesenchymal-epithelial transition Liver metastasis Markers Surgical and non-surgical therapies 
Expression of hepatocyte nuclear factor 4 alpha,wingless-related integration site,andβ-catenin in clinical gastric cancer
《World Journal of Clinical Cases》2022年第21期7242-7255,共14页Qian Hu Ling-Li Li Ze Peng Ping Yi 
Supported by National Natural Science Foundation of China,No.81673757.
BACKGROUND Gastric cancer(GC)is the second most common cause of cancer-related deaths worldwide.Hepatocyte nuclear factor 4 alpha(HNF4α)that belongs to the nuclear hormone receptor superfamily,is overexpressed in GC ...
关键词：Β-CATENIN BIOMARKER Gastric cancer Hepatocyte nuclear factor 4 alpha Wingless-related integration site 
分泌型卷曲相关蛋白5与冠心病、2型糖尿病关系的研究进展被引量：6
《中西医结合心脑血管病杂志》2021年第21期3694-3698,共5页常海瑶 李兴 
综述分泌型卷曲相关蛋白5(SFRP5)与冠心病、2型糖尿病关系的研究进展。糖尿病作为冠心病的等效危险因素,二者关系密切,存在肥胖、慢性炎症等诸多共同的病理环节。SFRP5作为脂肪细胞分泌的一种抗炎脂肪因子,可通过调节代谢紊乱、抑制炎...
关键词：冠心病 2型糖尿病 分泌型卷曲相关蛋白5 动脉粥样硬化 Wingless整合蛋白(Wnt) 综述 
Expression and function of WNT4 involved in larvae development and limb regeneration in Portunus trituberculatus被引量：2
《Journal of Oceanology and Limnology》2021年第1期306-316,共11页Zhiming REN Yuanyuan FU Lei LIU Xiao LIU Chunlin WANG 
Supported by the National Natural Science Foundation of China(No.31602152);the Major Agriculture Program of Ningbo(No.2017C110007);the K.C.Wong Magana Fund in Ningbo University.The funding body had no role in the study design,experimental implementation,interpretation of data,or writing of the manuscript。
The wingless-related integration site(WNT)proteins are a family of secreted glycoproteins that are evolutionarily conserved and are believed to be involved in evolution in vertebrates and invertebrates.WNT signaling p...
关键词：wingless-type MMTV integration site family member-4(WNT4) limb regeneration larvae development Portunus trituberculatus expression pattern RNAi 
Relationship between serum Dickkopf-1 and albuminuria in patients with type 2 diabetes被引量：1
《World Journal of Diabetes》2021年第1期47-55,共9页Ning-Ning Hou Cheng-Xia Kan Na Huang Yong-Ping Liu En-Wen Mao Yu-Ting Ma Fang Han Hong-XiSun Xiao-Dong Sun 
Supported by National Natural Science Foundation of China,No.81870593;Natural Science Foundation of Shandong Province of China,No.ZR2018MH008;Shandong Province Higher Educational Science and Technology Program for Youth Innovation,No.2020KJL004;Municipal Science and Technology Development Program of Weifang,No.2018YX025.
BACKGROUND Diabetic kidney disease is a microvascular complication of diabetes with complex pathogenesis.Wingless signaling-mediated renal fibrosis is associated with diabetic kidney disease.Dickkopf-1,a negative regu...
关键词：DICKKOPF-1 ALBUMINURIA Diabetic kidney disease Type 2 diabetic mellitus WINGLESS MICROALBUMINURIA 
Wnt/β-catenin通路及uPA在子宫内膜癌中的作用机制研究被引量：2
《实验与检验医学》2020年第4期618-621,625,共5页张玉洲 孙少霖 杨璇 
国家重点研发计划“精准医学研究”项目,编号2017YFC0909902;河南省科技计划项目,编号122102310098。
目的探究Wingless/β-连环蛋白(Wnt/β-catenin)通路及尿激酶型纤溶酶原激活剂(uPA)在子宫内膜癌(EC)中的作用机制。方法将人EC细胞KLE分为5组,即对照组、阴性对照组、Wnt-1组、si-uPA组和Wnt-1+si-uPA组,其中Wnt-1组通过转染Wnt-1 pcDN...
关键词：子宫内膜癌 Wingless/β-连环蛋白 尿激酶型纤溶酶原激活剂 迁移 侵袭 
灵活操控果蝇翅芽中wingless基因表达水平的策略被引量：1
《昆虫学报》2019年第9期1048-1053,共6页张徐波 武文君 李开霞 马恩波 吴海花 张建珍 董玮 
国家自然科学基金项目(NSFC31402021);山西省优秀人才科技创新项目(201805D211019)
【目的】灵活操控靶基因的表达水平对于研究基因的功能十分重要。Gal4/UAS系统已被广泛应用于调控基因表达,可研究果蝇Drosophila等模式生物复杂的生物学问题。受采用载体的特性及插入位点的影响,Gal4或UAS转基因品系在构建好之后,其调...
关键词：果蝇 转基因 靶基因 翅芽 WINGLESS 表达水平 温度 
A wingless species of the genus Hemithyrsocera Saussure(Blattodea:Ectobiidae) from China
《Zoological Systematics》2019年第2期123-131,共9页Sainan Zhang Xianwei Liu Kai Li 
sponsored by the Science-technology basic condition platform from The Ministry of Science and Technology of People’s Republic of China(2005DKA21402)
A new species, Hemithyrsocera hemiptera sp. nov., is described from Southwest China, based on its shortened tegmina, and the lack of hind wings, including the illustrations of its habitus and male genitalia. A key to ...
关键词：Blattellinae Hemithyrsocera COCKROACH NEW SPECIES China 
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