T-LYMPHOCYTES

作品数：106被引量：430H指数：11
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相关领域：医药卫生更多>>
相关作者：张罗李晓玉方积年林歆胜邵宗鸿更多>>
相关机构：首都医科大学中国科学院中国科学院上海生命科学研究院天津医科大学总医院更多>>
相关期刊：《Journal of Biomedical Research》《International Journal of Biomathematics》《Cancer Biology & Medicine》《Burns & Trauma》更多>>
相关基金：国家自然科学基金北京市自然科学基金上海市自然科学基金国家重点基础研究发展计划更多>>
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Homoharringtonine promotes heart allograft acceptance by enhancing regulatory T cells induction in a mouse model
《Chinese Medical Journal》2024年第12期1453-1464,共12页Xia Qiu Hedong Zhang Zhouqi Tang Yuxi Fan Wenjia Yuan Chen Feng Chao Chen Pengcheng Cui Yan Cui Zhongquan Qi Tengfang Li Yuexing Zhu Liming Xie Fenghua Peng Tuo Deng Xin Jiang Longkai Peng Helong Dai 
supported by grants from the National Natural Science Foundation of China(Nos.82070776,81900370,81970655,82270796,and 82200849);the Science and Technology Innovation Program of Hunan Province(No.2022RC3071);the Natural Science Foundation of Hunan Province(Nos.2021JJ30946 and 2022JJ30808)
Background:Homoharringtonine(HHT)is an effective anti-inflammatory,anti-viral,and anti-tumor protein synthesis inhibitor that has been applied clinically.Here,we explored the therapeutic effects of HHT in a mouse hear...
关键词：Heart transplantation HOMOHARRINGTONINE Immunosuppressive agents T-lymphocytes Regulatory Graft acceptance 
Regulatory T cells and cardiovascular diseases被引量：2
《Chinese Medical Journal》2023年第23期2812-2823,共12页Wangling Hu Jingyong Li Xiang Cheng 
National Natural Science Foundation of China(Nos.82030016 and 82230011 to Xiang Cheng and No.82000443 to Jingyong Li)
Inflammation is a major underlying mechanism in the progression of numerous cardiovascular diseases(CVDs).Regulatory T cells(Tregs)are typical immune regulatory cells with recognized immunosuppressive properties.Despi...
关键词：Adoptive transfer Aortic aneurysm abdominal ATHEROSCLEROSIS Cardiovascular diseases Hypertension T-lymphocytes regulatory 
Weak SARS-CoV-2-specific responses of TIGIT-expressing CD8^(+)T cells in people living with HIV after a third dose of a SARS-CoV-2 inactivated vaccine被引量：2
《Chinese Medical Journal》2023年第24期2938-2947,共10页Junyan Jin Xiuwen Wang Yongzheng Li Xiaodong Yang Hu Wang Xiaoxu Han Jin Sun Zhenglai Ma Junyi Duan Guanghui Zhang Tao Huang Tong Zhang Hao Wu Xin Zhang Bin Su 
supported by Beijing Natural Science Foundation(No.L222068 to Bin Su);the National Natural Science Foundation of China(NSFC,No.82272319 to Hu Wu,and No.81974303 to Bin Su);the High-Level Public Health Specialized Talents Project of Beijing Municipal Health Commission(No.2022-2-018 to Bin Su,and No.2022-1-007 to Tong Zhang);the Climbing the peak(Dengfeng)Talent Training Program of Beijing Hospitals Authority(No.DFL20191701 to Tong Zhang);the Beijing Health Technologies Promotion Program(No.BHTPP202002 to Tong Zhang);Beijing Key Laboratory for HIV/AIDS Research(No.BZ0089).
Background:T-cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibition motif domains(TIGIT),an inhibitory receptor expressed on T cells,plays a dysfunctional role in antiviral infection and ...
关键词：HIV TIGIT T-LYMPHOCYTES SARS-CoV-2 Booster vaccination Immunity 
Interferon-γpriming enhances the therapeutic effects of menstrual blood-derived stromal cells in a mouse liver ischemia-reperfusion model被引量：2
《World Journal of Stem Cells》2023年第9期876-896,共21页Qi Zhang Si-Ning Zhou Jia-Min Fu Li-Jun Chen Yang-Xin Fang Zhen-Yu Xu Hui-Kang Xu Yin Yuan Yu-Qi Huang Ning Zhang Yi-Fei Li Charlie Xiang 
National Key R&D Program of China,No.2022YFA1105603 and 2022YFC2304405;Hangzhou Science and Technology Project,China,No.20200224;National Natural Science Foundation of China,No.81900563;Key Research&Development Plan of Zhejiang Province,China,No.2019C03015 and 2020C04016。
BACKGROUND Mesenchymal stem cells(MSCs)have been used in liver transplantation and have certain effects in alleviating liver ischemia-reperfusion injury(IRI)and regulating immune rejection.However,some studies have in...
关键词：Mesenchymal stem cells Cell therapy Reperfusion injury T-LYMPHOCYTES AUTOPHAGY Liver 
Relationship between Circulating Plasma Galectin-3 Levels and T-Cell Activation during Cervical Cancer Chemotherapy
《Open Journal of Immunology》2023年第1期14-31,共18页Folly M. Gaba Maïmouna Diop Doudou G. M. Niang Sidy Ka Doudou Diouf Moussa Ndour Comlan J. G. Montcho Moustapha Mbow Babacar Faye Rokhaya N. Diallo Maguette S. Niang Ahmadou Dem Babacar Mbengue Alioune Dieye 
Objective: Despite the existence of several therapeutic strategies, the management of cervical cancer remains challenging. Our region has very little data on the interaction between the immune system and the clinical ...
关键词：Uterine Cervical Neoplasm CHEMOTHERAPY Galectin 3 T-Lymphocytes Activation 
外周血CD8^(+)T淋巴细胞亚群检测对过敏性鼻炎临床疗效的评估价值被引量：1
《中国耳鼻咽喉头颈外科》2023年第3期195-198,共4页麻琼钒 杜慧慧 郑国君 施正贤 潘晓浩 
温州市科技计划项目(Y20210318)。
目的探讨外周血CD8^(+)T淋巴细胞亚群检测对过敏性鼻炎(AR)临床疗效的评估价值。方法前瞻性选取2021年3月~2022年2月温州市中西医结合医院耳鼻咽喉科门诊治疗的120例AR患者和40例健康志愿者,分别设为研究组和对照组,比较两组外周血CD8^(...
关键词：鼻炎 过敏(Rhinitis Allergic) T淋巴细胞亚群(T-Lymphocyte Subsets) CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes) 治疗结果(Treatment Outcome) CD8阳性T淋巴细胞(CD28-positive T-lymphocytes) 
Esophageal lichen planus:Current knowledge,challenges and future perspectives
《World Journal of Gastroenterology》2022年第41期5893-5909,共17页Annegrit Decker Franziska Schauer Adhara Lazaro Carmen Monasterio Arthur Robert Schmidt Annette Schmitt-Graeff Wolfgang Kreisel 
Lichen planus(LP)is a frequent,chronic inflammatory disease involving the skin,mucous membranes and/or skin appendages.Esophageal involvement in lichen planus(ELP)is a clinically important albeit underdiagnosed inflam...
关键词：Lichen planus ESOPHAGITIS T-LYMPHOCYTES BUDESONIDE DYSPHAGIA Precancerosis 
Bifidobacterium infantis regulates the programmed cell death 1 pathway and immune response in mice with inflammatory bowel disease被引量：1
《World Journal of Gastroenterology》2022年第26期3164-3176,共13页Lin-Yan Zhou Ying Xie Yan Li 
Supported by the Doctoral Start-up Foundation of Liaoning Province,No.2021-BS-114.
BACKGROUND Inflammatory bowel disease(IBD)is caused by an abnormal immune response.Programmed cell death 1(PD-1)is an immunostimulatory molecule,which interacts with PD ligand(PD-L1)playing a prime important role amon...
关键词：Bifidobacterium infantis ENTERITIS Programmed cell death ligand T-LYMPHOCYTES 
Sterile alpha motif and histidine-aspartic acid domain-containing protein 1 expression and its relationship with T cell activation in human immunodeficiency virus/acquired immune deficiency syndrome patients with lung-spleen Qi deficiency syndrome pattern被引量：1
《Journal of Traditional Chinese Medicine》2022年第3期451-457,共7页LIU Zhen ZHANG Qingyan DENG Bowen SANG Feng WANG Danni KANG Ning LI Jie ZHANG Min LIANG Shoupei DUAN Chenchen LIU Zhibin XU Qianlei LI Qiang 
Supported by the National Natural Science Foundation of China(Construction of HIV Pseudovirus Infected Cell Model and Application of Yiaikang in the Study of T Cell Immune Response,No.82004207);the National Special Science and Technology Program on Major Infectious Diseases(Study on the Scheme of TCM to Reduce the Incidence of Adverse Reactions to AIDS Antiviral Therapy,No.2017ZX10205502002;Study on the Scheme of TCM to Reduce the Incidence of AIDS Opportunistic Infection,No.2017ZX10205502003);the Science and Technology Tackling Plan of Henan Province(Exploring the Activation Mechanism of Yiaikang on CD8+T Lymphocytes in HIV/AIDS Patients based on STING/SAMHD1 Pathway,No.202102310178;Regulation of HIV/AIDS Treg CellDerived Exosomeso on Activation of CD4+T Cells and the Intervention of Yiaikang,No.212102311126);Subject Construction Project of Henan Characteristic Backbone Subject of TCM of Henan University of TCM(Deep Sequencing/Molecular Docking/Gene Editing Network System to Analyze The Mechanism of TCM Regulating the Immune Function of HIV Patients,No.STG-ZYXKY-2020029);Henan Province TCM Research Project(Explore the Mechanism of Yiaikang in the Treatment of AIDS Immunity Based on HIV gag-CTL Response,No.2018JDZX106,2019AZB003;Study on TCM Treatment of Aged AIDS,No.20-21ZYZD03);Key Scientific Research Projects of Colleges and Universities in Henan Province(to Explore the Regulation Mechanism of Yiaikang on AIDS Lung Qi Deficiency Syndrome from TGF-β/Smad/ID,No.20A360010)
OBJECTIVE:To investigate the relationship between antiviral restriction factor Sterile Alpha Motif and Histidine-Aspartic acid domain-containing protein 1(SAMHD1)expression and T cell activation,furthermore,identifyin...
关键词：HIV acquired immunodeficiency syndrome symptoms complex SAM domain and HD domain-containing protein 1 T-LYMPHOCYTES 
Efficacy of Wumei Baijiang prescription(乌梅败酱方)on regulatory T cells/helper T cells Immune balance in mice with ulcerative colitis被引量：6
《Journal of Traditional Chinese Medicine》2022年第1期30-38,共9页SU Xiaolan ZHANG Tao GUO Song WANG Xin CHEN Lin WEI Wei 
Supported by Nation Science(Mechanism Study on Prevention and Relief Effects of Heat-clearing,Humidity-resolving and Pivot-regulating Methods on Model Mice Based on the Change of Intestinal Mucosal Barrier,No.81973638);Major National Disease-JiuLi(Ulcerative Colitis)Cooperation between Chinese and Western Medicine Pilot Project。
OBJECTIVE:To observe the therapeutic effect of Wumei Baijiang prescription(乌梅败酱方),empirical prescription of Lu Zhizheng,on experimental ulcerative colitis(UC)mice,and to investigate the mechanism of the prescript...
关键词：COLITIS ULCERATIVE MESALAMINE T-LYMPHOCYTES regulatory Th17 cells Wumei Baijiang prescription 
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