云南高校图书馆联盟文献共享服务平台- HOMOHARRINGTONINE

HOMOHARRINGTONINE: 作品数：25被引量：85H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：胥彬张健黄来强陶荣杨萍更多>>; 相关机构：中国科学院广西大学浙江大学医学院附属第一医院上海交通大学医学院附属新华医院更多>>; 相关期刊：《Chinese Medical Journal》《Acta Biochimica et Biophysica Sinica》《Chinese Journal of Cancer Research》《上海交通大学学报（医学版）》更多>>; 相关基金：国家自然科学基金浙江省自然科学基金更多>>

Homoharringtonine promotes heart allograft acceptance by enhancing regulatory T cells induction in a mouse model: 《Chinese Medical Journal》2024年第12期1453-1464,共12页Xia Qiu Hedong Zhang Zhouqi Tang Yuxi Fan Wenjia Yuan Chen Feng Chao Chen Pengcheng Cui Yan Cui Zhongquan Qi Tengfang Li Yuexing Zhu Liming Xie Fenghua Peng Tuo Deng Xin Jiang Longkai Peng Helong Dai; supported by grants from the National Natural Science Foundation of China(Nos.82070776,81900370,81970655,82270796,and 82200849);the Science and Technology Innovation Program of Hunan Province(No.2022RC3071);the Natural Science Foundation of Hunan Province(Nos.2021JJ30946 and 2022JJ30808); Background:Homoharringtonine(HHT)is an effective anti-inflammatory,anti-viral,and anti-tumor protein synthesis inhibitor that has been applied clinically.Here,we explored the therapeutic effects of HHT in a mouse hear...; 关键词：Heart transplantation HOMOHARRINGTONINE Immunosuppressive agents T-lymphocytes Regulatory Graft acceptance

Combination of eriocalyxin B and homoharringtonine exerts synergistic anti-tumor effects against t(8;21) AML: 《Acta Pharmacologica Sinica》2024年第3期633-645,共13页Yi-chen Lei Xin-jie Chen Yu-ting Dai Bing Dai Ji-yue Wang Miao-hui Li Ping Liu Han Liu Kan-kan Wang Lu Jiang Bing Chen; supported by the National Natural Science Foundation of China(81670137);Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support(20152501);State Key Laboratory of Medical Genomics Support(201802);Jiading District Health Commission Chinese Medicine Youth Research Support(2019-QN-ZYY-03).; Understanding the molecular pathogenesis of acute myeloid leukemia(AML)with well-defined genomic abnormalities has facilitated the development of targeted therapeutics.Patients with t(8;21)AML frequently harbor a fusi...; 关键词：t(8 21)AML RUNX1-RUNX1T1 KIT eriocalyxin B HOMOHARRINGTONINE synergistic effect

Effects of Homoharringtonine on the Proliferation and Apoptosis of Melanoma Cells: 《Medicinal Plant》2023年第6期6-10,共5页Rong HU Bin LIU Fan XIAO Xianjing ZENG; Supported by the Science and Technology Planning Project of Health Commission of Jiangxi Province(SKJP220229261).; [Objectives]To explore the effects of homoharringtonine(HHT)on the proliferation and apoptosis of melanoma cells.[Methods]Mouse melanoma cell line B16F10 was divided into 5 dfferent dose groups,among which Oμg/mL HHT...; 关键词：Homoharingtonine MELANOMA Matrix metlloproteinases CYELIN

Treatment of STAT5b-RARA positive acute promyelocytic leukemia by Venetoclax combining with homoharringtonine, cytarabine: A case report and literature review被引量：2: 《Blood Science》2022年第2期93-96,共4页Guangji Zhang Yang Song Li Wan Kaiqi Liu Shaowei Qiu Jianxiang Wang Yingchang Mi; The authors would like to appreciate the funding of National Key Research and Development Program of China(2019YFC0840605).; Introduction:Acute promyelocytic leukemia(APL)is mostly due to the chromosome translocation t(15;17)(q22;q12),leading to the formation of PML-RARA fusion protein.Some patients carried rare translocation involving RARA...; 关键词：Acute promyelocytic leukemia(APL) Case report Nested PCR STAT5b-RARA Venetoclax

Homoharringtonine is a safe and effective substitute for anthracyclines in children younger than 2 years old with acute myeloid leukemia被引量：4: 《Frontiers of Medicine》2019年第3期378-387,共10页Xiaoxiao Chen Yanjing Tang Jing Chen Ru Chen Longjun Gu Huiliang Xue Ci Pan Jingyan Tang Shuhong Shen; the National Natural Science Foundation of China (No.81270623);the Science and Technology Commission of Shanghai Municipality (No.14411950600);the Public Health 3-Year Project of Shanghai Children's Medical Center(No.GWIV-25).; Homoharringtonine (HHT),a plant alkaloid from Cephalotaxus harringtonia,exhibits a unique anticancer mechanism and has been widely used in China to treat patients with acute myeloid leukemia (AML) since the 1970s.Tria...; 关键词：HOMOHARRINGTONINE acute MYELOID leukemia PEDIATRICS

Homoharringtonine synergy with oridonin in treatment of t(8;21) acute myeloid leukemia被引量：7: 《Frontiers of Medicine》2019年第3期388-397,共10页Weina Zhang Ying Lu Tao Zhen Xinjie Chen Ming Zhang Ping Liu Xiangqin Weng Bing Chen Yueying Wang; Collaboration of c-KIT mutations with AML1-ETO (AE) has been demonstrated to induce t(8;21) acute myeloid leukemia (AML).Targeted therapies designed to eliminate AE and c-KIT oncoproteins may facilitate effective trea...; 关键词：AML1-ETO C-KIT HOMOHARRINGTONINE ORIDONIN t(8 21) AML SYNERGISTIC effect

A phase Ⅳ study of homoharringtonine, cytarabine, aclacinomycin and G-CSF(HCAG) regimen compared with traditional IA regimen in the treatment of newly diagnosed elderly acute myeloid leukemia patients被引量：1: 《上海交通大学学报（医学版）》2017年第8期1100-1105,共6页刘钊张赟翔王丽宁 XIA Zheng MAO Yuan-fei ZHAO Hui-jin YOU Jian-hua YU Yang ZHAO Yu-bing REN Yu-hong LI Ya WANG Yan CHEN Qiu-sheng 李军民陈瑜; National Natural Science Foundation of China(81270621,81300451);National Public Health Grand Research Foundation(201202003);Shanghai Health System Advanced and Appropriate Technology Promotion Projects(2013SY001);Multiple Clinical Research Center Program of Shanghai Jiao Tong University School of Medicine(DLY201513); Objective · To compare the efficacy and prognostic factors of HCAG regimen with traditional IA regimen in the treatment of newly diagnosed elderly acute myeloid leukemia(AML) patients. Methods · Forty-one patients w...; 关键词：HOMOHARRINGTONINE long-term survival risk factors acute myeloid leukemia elderly patient

Homoharringtonine in newly diagnosed acute promyelocytic leukemia treatment: a prospective,randomized controlled trial: 《China Medical Abstracts(Internal Medicine)》2016年第2期54-,共1页王迎; Objective To compare the efficacy and toxicities of combining homoharringtonine(HHT)±daunorubicin(DNR)with all-transretinoic acid(ATRA)based therapy and DNR plus ATRA based therapy in newly diagnosed low/intermediate...; 关键词：ATRA PROSPECTIVE REMISSION MEDIAN COUNTS consolidation induction shorter BASELINE

Efficacy and safety of homoharringtonine during consolidation therapy in chronic myeloid leukemia: a meta-analysis: 《Journal of Chinese Pharmaceutical Sciences》2014年第10期716-722,共7页田怀平杨萍陶荣张金莲张健; In the present study, we aimed to assess the efficacy and safety of Homoharringtonine （HHT） for chronic myelogenous leukemia （CML）. Databases, such as PubMed, the Cochrane Library, EMbase, CENTRAL, VIP, WanFang Da...; 关键词：HOMOHARRINGTONINE Omacetaxine Chronic myelogenous leukemia META-ANALYSIS

高三尖杉酯碱(Homoharringtonine)抗癌研究新进展被引量：13: 《肿瘤药学》2013年第3期162-165,231,共5页胥彬; 高三尖杉酯碱是三尖杉属植物（Cepha lotaxus）中的一种有效抗癌成分。此植物为我国特产树种[1],国内有8种,4个变种,广泛分布在长江以南地区,资源丰富,民间曾用于治疗肿瘤。PowellRG等[2]于1972年从Cephalotaxus harringtonia（日本粗...; 关键词：高三尖杉酯碱抗癌成分抗癌活性临床试验生物碱先发现植物

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