ARSENICALS

作品数:21被引量:161H指数:6
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相关作者:邬维礼李俊娥王振义刘陕西王怀宇更多>>
相关机构:西安交通大学医学院第一附属医院武汉大学上海第二医科大学附属瑞金医院上海交通大学医学院附属瑞金医院更多>>
相关期刊:《Science China(Life Sciences)》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Advances in Biological Chemistry》更多>>
相关基金:国家自然科学基金中国博士后科学基金更多>>
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Hyperthermia promotes degradation of the acute promyelocytic leukemia driver oncoprotein ZBTB16/RARα被引量:1
《Acta Pharmacologica Sinica》2023年第4期822-831,共10页Qian-qian Wang Liaqat Hussain Pei-han Yu Chang Yang Chen-ying Zhu Ya-fang Ma Si-chun Wang Tao Yang Yuan-yuan Kang Wen-juan Yu Yasen Maimaitiyiming Hua Naranmandura 
supported by grants from the National Natural Science Foundation of China(No.81872942,82003875,82000155,82000145,82200160);the China Postdoctoral Science Foundation(No.2021M702875,2021M702877);the Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang,Grant/Award Number:2020R01006.
The acute promyelocytic leukemia(APL)driver ZBTB16/RARαis generated by the t(11;17)(q23;q21)chromosomal translocation,which is resistant to combined treatment of all-trans retinoic acid(ATRA)and arsenic trioxide(ATO)...
关键词:acute promyelocytic leukemia ZBTB16/RARαfusion protein HYPERTHERMIA PROTEOLYSIS nuclear receptor corepressors ARSENICALS 
Thiolated arsenicals in arsenic metabolism: Occurrence,formation, and biological implications被引量:6
《Journal of Environmental Sciences》2016年第11期59-73,共15页Yuzhen Sun Guangliang Liu Yong Cai 
sponsored by the National Natural Science Foundation of China (No. 91543103)
Arsenic(As) is a notoriously toxic pollutant of health concern worldwide with potential risk of cancer induction, but meanwhile it is used as medicines for the treatment of different conditions including hematologic...
关键词:Arsenic Thioarsenicals Occurrence Formation pathways Toxicity 
Comparative cytotoxicity of fourteen trivalent and pentavalent arsenic species determined using real-time cell sensing被引量:23
《Journal of Environmental Sciences》2016年第11期113-124,共12页Birget Moe Hanyong Peng Xiufen Lu Baowei Chen Lydia W.L.Chen Stephan Gabos Xing-Fang Li X.Chris Le 
supported by Alberta Health, Alberta Innovates, the Canada Research Chairs Program;the Canadian Institutes of Health Research (CIHR);the Natural Sciences and Engineering Research Council (NSERC) of Canada
The occurrence of a large number of diverse arsenic species in the environment and in biological systems makes it important to compare their relative toxicity. The toxicity of arsenic species has been examined in vari...
关键词:Arsenic species Thio-arsenicals Methylarsenicals Phenylarsenicals Toxicity Real-time sensing 
Permeation of roxarsone and its metabolites increases caco-2 cell proliferation
《Advances in Biological Chemistry》2013年第4期389-396,共8页Gladys S. Bayse Latanya P. Hammonds-Odie Kimberly M. Jackson Deidre K. Tucker Ward G. Kirlin 
The benzenearsonate, Roxarsone, has been used since 1944 as an antimicrobial, growth-promoting poultry feed additive. USGS and EPA report that Roxarsone (4-hydroxy-3-nitrobenzenearsonate) and metabolites, including AH...
关键词:Benzenearsonates ROXARSONE Phenylarsonates ARSENICALS CACO-2 
Arsenic trioxide: safety issues and their management被引量:7
《Acta Pharmacologica Sinica》2008年第3期296-304,共9页Wing-Yan AU Yok-Lam KWONG 
Arsenic trioxide (As2O3) has been used medicinally for thousands of years. Its therapeutic use in leukaemia was described a century ago. Recent rekindling in the interest of As2O3 is due to its high efficacy in acut...
关键词:ARSENICALS antitumor pharmacology PRODRUGS drug design 
Gene Expression Profile of Multiple Myeloma Cell Line Treated by Arsenic Trioxide
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2007年第6期646-649,共4页王梦昌 刘陕西 刘蓬勃 
the Science Foundation of Shaanxi Province (No. 2001-KG9).
cDNA microarray was used to compare the gene expression profiles of multiple myeloma cell line RPMI8226 24 h before and after treatment with arsenic trioxide. Two cDNA probes were prepared by mRNA reverse transcriptio...
关键词:multiple myeloma gene expression ARSENICALS arsenic trioxide 
Effects of arsenic trioxide on voltage-dependent potassium channels and on cell proliferation of human multiple myeloma cells被引量:6
《Chinese Medical Journal》2007年第14期1266-1269,共4页ZHOU Jin WANG Wei WEI Qing-fang FENG Tie-ming TAN Li-jun YANG Bao-feng 
Arsenic trioxide (ATO) can induce cellular apoptosis ,and inhibit the activities of multiple myeloma (MM)cells in vitro, but how it works is not very clear. Recent studies showed that ATO worked on the voltagedepe...
关键词:multiple myeloma ARSENICALS ion channel cell cycle PROLIFERATION 
Various tolerances to arsenic trioxide between human cortical neurons and leukemic cells被引量:6
《Science China(Life Sciences)》2006年第6期567-572,共6页ZHOU Jin1,MENG Ran1,2,SUI Xinhua2,LI Wenbin3 & YANG Baofeng1 1.The First Hospital of Harbin Medical University,Harbin 150001,China 2. Shijitan Hospital,The Ninth Clinical Medical College of Peking University,Beijing 100038,China 3. Xuanwu Hospital,Capital University of Medical Sciences,Beijing 100053,China 
supported by the National Natural Science Foundation of China(Grant No.30370507);the Key Projects Foundation of Harbin Science and Technology Commission(Grant No.2003AA9CS188-12).
Arsenic trioxide (As2O3) is very effective for treatment of acute promyelocytic leukaemia (APL) but little can pass through the blood-brain-barrier (BBB),which limits its use in the prevention and treatment of central...
关键词:arsenicals  protein KINASE C  NEURONE specific enolase. 
REPEATED ARSENIC TRIOXIDE INTRAVENOUS INFUSION CAUSES FOCAL BONE MARROW NECROSIS IN TWO ACUTE PROMYELOCYTIC LEUKEMIA PATIENTS被引量:1
《Chinese Medical Sciences Journal》2004年第4期281-281,共1页JinZhou RanMeng Xin-huaSui Bao-fengYang 
关键词:Adult Antineoplastic Agents ARSENICALS Bone Marrow Bone Marrow Diseases Child Female Humans Infusions  Intravenous Leukemia  Promyelocytic  Acute Male NECROSIS Oxides 
Comparing two arsenic trioxide administration methods in APL therapy被引量:18
《Chinese Medical Journal》2004年第9期1411-1413,共3页周晋 孟然 杨宝峰 
ThesubjectwassupportedbytheNationalNaturalScienceFoundation(No 3 0 3 70 5 0 7)
关键词:Arsenicals · leukemia myelocyte acute · administration 
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